Results 31 to 40 of about 68,956 (338)

Crosslink between lipids and acute uveitis: a lipidomic analysis [PDF]

open access: yesInternational Journal of Ophthalmology, 2018
AIM: To explore the roles of phospholipids and sphingolipids in the inflammatory process of uveitis. METHODS: Aqueous humor (AH) and the retina were obtained from endotoxin-induced uveitis (EIU) rats during the acute inflammation stage (24h after ...
Hai-Yan Wang   +5 more
doaj   +1 more source

Lipidomics of the chicken egg yolk: high-resolution mass spectrometric characterization of nutritional lipid families

open access: yesPoultry Science, 2021
While previous studies have characterized the fatty acids and global lipid families of the chicken egg yolk, there have been no publications characterizing the individual lipids in these lipid families.
Paul L. Wood   +12 more
doaj   +1 more source

Current Trends and Changes in Use of Membrane Molecular Dynamics Simulations within Academia and the Pharmaceutical Industry

open access: yesMembranes, 2023
There has been an almost exponential increase in the use of molecular dynamics simulations in basic research and industry over the last 5 years, with almost a doubling in the number of publications each year.
Stephan L. Watkins
doaj   +1 more source

Nanofiber-Based Delivery of Bioactive Lipids Promotes Pro-regenerative Inflammation and Enhances Muscle Fiber Growth After Volumetric Muscle Loss

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Volumetric muscle loss (VML) injuries after extremity trauma results in an important clinical challenge often associated with impaired healing, significant fibrosis, and long-term pain and functional deficits.
Cheryl L. San Emeterio   +25 more
doaj   +1 more source

Sphingolipids in Food and the Emerging Importance of Sphingolipids to Nutrition [PDF]

open access: yesThe Journal of Nutrition, 1999
Eukaryotic organisms as well as some prokaryotes and viruses contain sphingolipids, which are defined by a common structural feature, i.e. , a "sphingoid base" backbone such as D-erythro-1,3-dihydroxy, 2-aminooctadec-4-ene (sphingosine). The sphingolipids of mammalian tissues, lipoproteins, and milk include ceramides, sphingomyelins, cerebrosides ...
Dirck L. Dillehay   +5 more
openaire   +3 more sources

Depletion of adipocyte sphingosine kinase 1 leads to cell hypertrophy, impaired lipolysis, and nonalcoholic fatty liver disease

open access: yesJournal of Lipid Research, 2020
Sphingolipids have become established participants in the pathogenesis of obesity and its associated maladies. Sphingosine kinase 1 (SPHK1), which generates S1P, has been shown to increase in liver and adipose of obese humans and mice and to regulate ...
Andrea K. Anderson   +6 more
doaj   +1 more source

Sterol transporters at membrane contact sites regulate TORC1 and TORC2 signaling. [PDF]

open access: yes, 2017
Membrane contact sites (MCSs) function to facilitate the formation of membrane domains composed of specialized lipids, proteins, and nucleic acids. In cells, membrane domains regulate membrane dynamics and biochemical and signaling pathways.
Murley, Andrew   +6 more
core   +1 more source

Sphingolipids in Major Depression [PDF]

open access: yesNeurosignals, 2015
Major depression is one of the most common and severe diseases affecting the world's population. However, the pathogenesis of the disease remains inadequately defined. Previously, a lack of monoaminergic neurotransmitters was the focus of pathophysiological concepts; however, recent concepts focus on a alteration of neurogenesis in the hippocampus ...
Jernigan, Peter L.   +6 more
openaire   +4 more sources

Sphingolipids in neurodegenerative diseases

open access: yesFrontiers in Neuroscience, 2023
Neurodegenerative Diseases (NDDs) are a group of disorders that cause progressive deficits of neuronal function. Recent evidence argues that sphingolipid metabolism is affected in a surprisingly broad set of NDDs. These include some lysosomal storage diseases (LSDs), hereditary sensory and autonomous neuropathy (HSAN), hereditary spastic paraplegia ...
Xueyang Pan   +8 more
openaire   +4 more sources

Ethylene modulates sphingolipid synthesis in Arabidopsis

open access: yesFrontiers in Plant Science, 2015
Sphingolipids have essential structural and bioactive functions in membranes and in signaling. However, how plants regulate sphingolipid biosynthesis in the response to stress remains unclear.
Jian-xin eWu   +4 more
doaj   +1 more source

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