Results 21 to 30 of about 57,321 (288)
Sphingolipids in mitochondria [PDF]
Sphingolipids are bioactive lipids found in cell membranes that exert a critical role in signal transduction. In recent years, it has become apparent that sphingolipids participate in growth, senescence, differentiation and apoptosis. The anabolism and catabolism of sphingolipids occur in discrete subcellular locations and consist of a strictly ...
María José Hernández-Corbacho +4 more
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Fumonisin B1: A Tool for Exploring the Multiple Functions of Sphingolipids in Plants
Fumonisin toxins are produced by Fusarium fungal pathogens. Fumonisins are structural analogs of sphingosine and potent inhibitors of ceramide synthases (CerSs); they disrupt sphingolipid metabolism and cause disease in plants and animals.
Hong-Yun Zeng, Chun-Yu Li, Nan Yao
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Crosslink between lipids and acute uveitis: a lipidomic analysis [PDF]
AIM: To explore the roles of phospholipids and sphingolipids in the inflammatory process of uveitis. METHODS: Aqueous humor (AH) and the retina were obtained from endotoxin-induced uveitis (EIU) rats during the acute inflammation stage (24h after ...
Hai-Yan Wang +5 more
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While previous studies have characterized the fatty acids and global lipid families of the chicken egg yolk, there have been no publications characterizing the individual lipids in these lipid families.
Paul L. Wood +12 more
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There has been an almost exponential increase in the use of molecular dynamics simulations in basic research and industry over the last 5 years, with almost a doubling in the number of publications each year.
Stephan L. Watkins
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A systematic simulation of the effect of salicylic acid on sphingolipid metabolism
The phytohormone salicylic acid (SA) affects plant development and defense responses. Recent studies revealed that SA also participates in the regulation of sphingolipid metabolism, but the details of this regulation remain to be explored.
Chao eShi +6 more
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Volumetric muscle loss (VML) injuries after extremity trauma results in an important clinical challenge often associated with impaired healing, significant fibrosis, and long-term pain and functional deficits.
Cheryl L. San Emeterio +25 more
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Sphingolipids in Food and the Emerging Importance of Sphingolipids to Nutrition [PDF]
Eukaryotic organisms as well as some prokaryotes and viruses contain sphingolipids, which are defined by a common structural feature, i.e. , a "sphingoid base" backbone such as D-erythro-1,3-dihydroxy, 2-aminooctadec-4-ene (sphingosine). The sphingolipids of mammalian tissues, lipoproteins, and milk include ceramides, sphingomyelins, cerebrosides ...
H, Vesper +5 more
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Cystic fibrosis (CF) is caused by mutations in the CF transmembrane conductance regulator (CFTR) that affect protein structure and channel function.
Hiroko Hamai +3 more
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Sphingolipids have become established participants in the pathogenesis of obesity and its associated maladies. Sphingosine kinase 1 (SPHK1), which generates S1P, has been shown to increase in liver and adipose of obese humans and mice and to regulate ...
Andrea K. Anderson +6 more
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