Results 21 to 30 of about 57,321 (288)

Sphingolipids in mitochondria [PDF]

open access: yesBiochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2017
Sphingolipids are bioactive lipids found in cell membranes that exert a critical role in signal transduction. In recent years, it has become apparent that sphingolipids participate in growth, senescence, differentiation and apoptosis. The anabolism and catabolism of sphingolipids occur in discrete subcellular locations and consist of a strictly ...
María José Hernández-Corbacho   +4 more
openaire   +2 more sources

Fumonisin B1: A Tool for Exploring the Multiple Functions of Sphingolipids in Plants

open access: yesFrontiers in Plant Science, 2020
Fumonisin toxins are produced by Fusarium fungal pathogens. Fumonisins are structural analogs of sphingosine and potent inhibitors of ceramide synthases (CerSs); they disrupt sphingolipid metabolism and cause disease in plants and animals.
Hong-Yun Zeng, Chun-Yu Li, Nan Yao
doaj   +1 more source

Crosslink between lipids and acute uveitis: a lipidomic analysis [PDF]

open access: yesInternational Journal of Ophthalmology, 2018
AIM: To explore the roles of phospholipids and sphingolipids in the inflammatory process of uveitis. METHODS: Aqueous humor (AH) and the retina were obtained from endotoxin-induced uveitis (EIU) rats during the acute inflammation stage (24h after ...
Hai-Yan Wang   +5 more
doaj   +1 more source

Lipidomics of the chicken egg yolk: high-resolution mass spectrometric characterization of nutritional lipid families

open access: yesPoultry Science, 2021
While previous studies have characterized the fatty acids and global lipid families of the chicken egg yolk, there have been no publications characterizing the individual lipids in these lipid families.
Paul L. Wood   +12 more
doaj   +1 more source

Current Trends and Changes in Use of Membrane Molecular Dynamics Simulations within Academia and the Pharmaceutical Industry

open access: yesMembranes, 2023
There has been an almost exponential increase in the use of molecular dynamics simulations in basic research and industry over the last 5 years, with almost a doubling in the number of publications each year.
Stephan L. Watkins
doaj   +1 more source

A systematic simulation of the effect of salicylic acid on sphingolipid metabolism

open access: yesFrontiers in Plant Science, 2015
The phytohormone salicylic acid (SA) affects plant development and defense responses. Recent studies revealed that SA also participates in the regulation of sphingolipid metabolism, but the details of this regulation remain to be explored.
Chao eShi   +6 more
doaj   +1 more source

Nanofiber-Based Delivery of Bioactive Lipids Promotes Pro-regenerative Inflammation and Enhances Muscle Fiber Growth After Volumetric Muscle Loss

open access: yesFrontiers in Bioengineering and Biotechnology, 2021
Volumetric muscle loss (VML) injuries after extremity trauma results in an important clinical challenge often associated with impaired healing, significant fibrosis, and long-term pain and functional deficits.
Cheryl L. San Emeterio   +25 more
doaj   +1 more source

Sphingolipids in Food and the Emerging Importance of Sphingolipids to Nutrition [PDF]

open access: yesThe Journal of Nutrition, 1999
Eukaryotic organisms as well as some prokaryotes and viruses contain sphingolipids, which are defined by a common structural feature, i.e. , a "sphingoid base" backbone such as D-erythro-1,3-dihydroxy, 2-aminooctadec-4-ene (sphingosine). The sphingolipids of mammalian tissues, lipoproteins, and milk include ceramides, sphingomyelins, cerebrosides ...
H, Vesper   +5 more
openaire   +2 more sources

Defective CFTR increases synthesis and mass of sphingolipids that modulate membrane composition and lipid signaling

open access: yesJournal of Lipid Research, 2009
Cystic fibrosis (CF) is caused by mutations in the CF transmembrane conductance regulator (CFTR) that affect protein structure and channel function.
Hiroko Hamai   +3 more
doaj   +1 more source

Depletion of adipocyte sphingosine kinase 1 leads to cell hypertrophy, impaired lipolysis, and nonalcoholic fatty liver disease

open access: yesJournal of Lipid Research, 2020
Sphingolipids have become established participants in the pathogenesis of obesity and its associated maladies. Sphingosine kinase 1 (SPHK1), which generates S1P, has been shown to increase in liver and adipose of obese humans and mice and to regulate ...
Andrea K. Anderson   +6 more
doaj   +1 more source

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