Results 11 to 20 of about 35,165 (291)
Regulation of sphingolipid metabolism in the immune microenvironment of gastric cancer: current insights and future directions [PDF]
Frontiers in OncologyIn recent years, the role of sphingolipid metabolism in the tumor immune microenvironment has gradually gained attention, particularly in gastric cancer research.
Yunqi Hua +7 more
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Sphingolipid metabolism-related genes B4GALNT1 and CERS4 as prognostic biomarkers in lung adenocarcinoma. [PDF]
PLoS ONESphingolipid metabolism is an important component of various biological processes, particularly in cancer pathology. This metabolic pathway significantly influences the behavior of cancer cells by regulating growth, apoptosis, and survival.
Jieun Jeon +6 more
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Sphingolipid metabolism and obesity-induced inflammation [PDF]
Frontiers in Endocrinology, 2013 Obesity is a metabolic disorder developed by overnutrition and a major cause for insulin resistance and cardiovascular events. Since adipose tissue is one of the major sites for the synthesis and secretion of cytokines, enlarged adipose tissue in obese ...
Se-Chan eKang +3 more
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Sphingolipid metabolism-related genes as diagnostic markers in pneumonia-induced sepsis: the AUG model [PDF]
Scientific ReportsPneumonia-induced sepsis (PIS) is a life-threatening condition with high mortality rates, necessitating the identification of biomarkers and therapeutic targets.
Jing Wu +15 more
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HeliyonSphingolipid metabolism affects prognosis and resistance to immunotherapy in patients with cancer and is an emerging target in cancer therapy with promising diagnostic and prognostic value.
Xiaolan He +6 more
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Cells, 2023 Currently, there are no animal models for studying both specific social fear and social fear with comorbidities. Here, we investigated whether social fear conditioning (SFC), an animal model with face, predictive and construct validity for social anxiety
Iulia Zoicas +4 more
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Using BODIPY FL-Sphingolipid Analogs to Study Sphingolipid Metabolism in Mouse Embryonic Stem Cells
Bio-Protocol, 2022 Sphingolipids are important structural components of cellular membranes. They also function as prominent signaling molecules to control a variety of cellular events, such as cell growth, differentiation, and apoptosis.
Wei Fan, Xiaoling Li
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Effects of sphingolipid metabolism disorders on endothelial cells
Lipids in Health and Disease, 2022 Many cardiovascular disorders, including atherosclerosis, hypertension, coronary heart disease, diabetes, etc., are characterized by endothelial cell dysfunction.
Yali Lai +4 more
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Ceramide synthase CERS4 gene downregulation is associated with KRAS mutation in colorectal cancer
Scientific Reports, 2023 Ceramide, the central molecule in sphingolipid synthesis, is a bioactive lipid that serves as a regulatory molecule in the anti-inflammatory responses, apoptosis, programmed necrosis, autophagy, and cell motility of cancer cells.
Tamuro Hayama +10 more
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Frontiers in Oncology, 2022 Biologically active sphingolipids are closely related to the growth, differentiation, aging, and apoptosis of cancer cells. Some sphingolipids, such as ceramides, are favorable metabolites in the sphingolipid metabolic pathway, usually mediating ...
Run-Ze Li +19 more
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