Results 31 to 40 of about 35,165 (291)
Scientific Reports, 2022 Omega-3 polyunsaturated fatty acids (n-3 PUFAs) are essential nutrients that can affect inflammatory responses. While n-3 PUFAs are generally considered beneficial for cardiovascular disease and obesity, the effects on asthma, the most common ...
Andrea Heras +13 more
doaj +1 more source
Sphingolipid Metabolism and Signalling Pathways in Heart Failure: From Molecular Mechanism to Therapeutic Potential. [PDF]
J Inflamm ResMeng Zhao,1– 3 Rutao Bian,2 Xuegong Xu,2 Junpeng Zhang,2 Li Zhang,2 Yi Zheng2 1The First Clinical Medical College of Henan University of Chinese Medicine, Zhengzhou, Henan Province, People’s Republic of China; 2Department of Cardiology, Zhengzhou ...
Zhao M +5 more
europepmc +2 more sources
Ceramide Metabolism Enzymes—Therapeutic Targets against Cancer
Medicina, 2021 Sphingolipids are both structural molecules that are essential for cell architecture and second messengers that are involved in numerous cell functions. Ceramide is the central hub of sphingolipid metabolism. In addition to being the precursor of complex
Ana Gomez-Larrauri +4 more
doaj +1 more source
Analysis of metabolites of fungal balls in the paranasal sinuses
BMC Infectious Diseases, 2022 Fungal ball sinusitis is characterized by complex fungus infections with non-invasive inflammation. But no research reported fungal ball composition and metabolic-related product types currently.
Xiaoqing Zhang +5 more
doaj +1 more source
Sphingolipid Metabolism and Neutral Sphingomyelinases [PDF]
, 2013 Sphingolipids are an important class of lipid molecules that play fundamental roles in our cells and body. Beyond a structural role, it is now clearly established that sphingolipids serve as bioactive signaling molecules to regulate diverse processes including inflammatory signaling, cell death, proliferation, and pain sensing. Sphingolipid metabolites
Michael V, Airola, Yusuf A, Hannun
openaire +2 more sources
Computational modeling of sphingolipid metabolism [PDF]
BMC Systems Biology, 2015 As suggested by the origin of the word, sphingolipids are mysterious molecules with various roles in antagonistic cellular processes such as autophagy, apoptosis, proliferation and differentiation. Moreover, sphingolipids have recently been recognized as important messengers in cellular signaling pathways.
Weronika Wronowska +3 more
openaire +2 more sources
Sphingolipids and their metabolism in physiology and disease [PDF]
Nature Reviews Molecular Cell Biology, 2017 Studies of bioactive lipids in general and sphingolipids in particular have intensified over the past several years, revealing an unprecedented and unanticipated complexity of the lipidome and its many functions, which rivals, if not exceeds, that of the genome or proteome.
Yusuf A, Hannun, Lina M, Obeid
openaire +2 more sources
Frontiers in Physiology, 2021 Aberrant sphingolipid metabolism contributes to cardiac pathophysiology. Emerging evidence found that an increased level of ceramide during the inflammatory phase of post-myocardial infarction (MI) served as a biomarker and was associated with cardiac ...
Tong Hua +4 more
doaj +1 more source
Autophagy in the light of sphingolipid metabolism [PDF]
Apoptosis, 2015 Maintenance of cellular homeostasis requires tight and coordinated control of numerous metabolic pathways, which are governed by interconnected networks of signaling pathways and energy-sensing regulators. Autophagy, a lysosomal degradation pathway by which the cell self-digests its own components, has over the past decade been recognized as an ...
Harvald, Eva Bang +2 more
openaire +2 more sources
A circular network of coregulated sphingolipids dictates lung cancer growth and progression
EBioMedicine, 2021 Background: Sphingolipid metabolism is among the top dysregulated pathways in non-small cell lung carcinomas (NSCLC). However, the molecular control of sphingolipid metabolic reprogramming in cancer progression remains unclear.
Qiong Meng +12 more
doaj +1 more source