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Sphingolipid Metabolites in Signal Transduction

2000
The importance of intracellular signaling molecules derived from sphingolipids, a major class of membrane lipids, has only recently begun to be appreciated. Sphingolipids contain a long-chain sphingoid base backbone, of which sphingosine is the most common; an amide-linked fatty acid; and a polar head group (hydroxyl for ceramide, phosphorylcholine for
Sarah Spiegel, Sheldon Milstien
openaire   +1 more source

Sphingolipids as Signaling and Regulatory Molecules

2010
1. An Overview of Sphingolipid Metabolism: From Synthesis to Breakdown Christopher R. Gault, Lina M. Obeid and Yusuf A. Hannun Abstract Sphingolipid Properties in Membranes De Novo Synthesis in the ER Ceramide Transport from the ER to the Golgi Synthesis of Complex Sphingolipids Ceramide Kinase and Ceramide?1?Phosphate Catabolizing Complex ...
openaire   +1 more source

Sphingolipid metabolism and complement signaling in cancer progression

Trends in Cancer, 2023
Alhaji H. Janneh   +2 more
exaly  

Time-Dependent Changes in Hepatic Sphingolipid Accumulation and PI3K/Akt/mTOR Signaling Pathway in a Rat Model of NAFLD

International Journal of Molecular Sciences, 2021
Karolina Konstantynowicz-Nowicka   +2 more
exaly  

The role of sphingolipids in the process of signal transduction

Progress in Lipid Research, 1997
L. Riboni   +4 more
openaire   +2 more sources

Identification of a Novel Role for Sphingolipid Signaling in TNF α and Ischemic Preconditioning Mediated Cardioprotection

Journal of Molecular and Cellular Cardiology, 2002
Sandrine Lecour, Brian Woodward
exaly  

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