Results 121 to 130 of about 8,799 (216)
Distinct CSF lipidomic profiles are associated with five proteomic subtypes in patients with Alzheimer's disease. [PDF]
Malliou G +11 more
europepmc +1 more source
Synthetic Cells on Demand: From Molecular Stimuli to Cellular Functions
ABSTRACT Synthetic cells constructed via bottom‐up approaches using lipid or polymer vesicles have become essential tools for mimicking cellular functions and studying synthetic biological systems. These vesicles can undergo morphological changes and trigger internal reactions in response to external stimuli, such as osmotic pressure, temperature, pH ...
Masato Suzuki, Koki Kamiya
wiley +1 more source
Metabolomic Signatures of MASLD Identified by the Fatty Liver Index Reveal Gamma-Glutamyl Cycle Disruption and Lipid Remodeling. [PDF]
Naja K, Anwardeen N, Elrayess MA.
europepmc +1 more source
ABSTRACT The stratum corneum, as the outermost layer of the skin, functions as a critical barrier that maintains cutaneous hydration and systemic homeostasis. Among its structural lipids, ceramides constitute the most abundant and diverse component. These molecules are essential for the formation of lamellar structures that secure barrier integrity ...
Takashi Sakai
wiley +1 more source
Resistant Potato Starch Supplementation Increases the Serum Levels of Choline and Sphingomyelins Without Affecting Trimethylamine Oxide Levels. [PDF]
Bush JR, Han J, Goodlett DR.
europepmc +1 more source
Intergenerational Transmission of Metabolic Changes in Oocytes From Aged Mice
This study shows that oxidative changes in oocytes from aged female mice lead to lipid droplet accumulation and altered energy and retinoid metabolism. These changes persist in embryonic organs, triggering antioxidant responses in lipid‐rich tissues. Remarkably, altered profiles are transmitted across generations, reaching third generation, suggesting ...
Hafsa Gulzar +8 more
wiley +1 more source
<i>In ovo</i> myo-inositol administration: impacts on growth performance and metabolic profiles in broiler chickens. [PDF]
Shomina N +3 more
europepmc +1 more source
Early‐life co‐consumption of galactose and glucose (hydrolyzed lactose) programs Drosophila melanogaster lifespan in a sex‐specific manner. Particularly, the co‐consumption of galactose and glucose programs extended lifespan when female flies were challenged by obesogenic diets later in life, and this is concomitant with remodeling of lipid metabolism,
Peixin Sun +7 more
wiley +1 more source
Drosophila and mouse models of Alzheimer's disease exhibit lipid accumulation and neuroinflammation, leading to progressive impairments in memory, locomotion, sleep, circadian rhythms, and synaptic integrity. Knockdown of Dgat2 reduces lipid accumulation and neuroinflammatory signaling, rescuing these deficits and highlighting a conserved, crossspecies
Archana Yadav +7 more
wiley +1 more source

