LPC18:0 secreted by exogenous neural stem cells potentiates neurogenesis via the GPR55/AKT/GSK3β signalling axis, which ultimately promotes spinal cord injury recovery. ABSTRACT Spinal cord injury (SCI) is a devastating condition with limited therapeutic options. Although neural stem cell (NSC) transplantation shows regenerative potential, its efficacy
Dong Chen +11 more
wiley +1 more source
The sphingosine-1-phosphate pathway is differentially activated in human gestational tissues. [PDF]
Mbadhi MN +6 more
europepmc +1 more source
Mechanistic insights and therapeutic potential of sphingosine‑1‑phosphate in the development of pulmonary fibrosis (Review). [PDF]
Qin Y, Tang C, Tan S, Liu G.
europepmc +1 more source
Structural insights into subtype-specific agonist recognition by sphingosine-1-phosphate receptors. [PDF]
Yu L +9 more
europepmc +1 more source
Abstract Objectives Oat lipids are rich in ceramides. In this investigation, we analysed the delivery of a specific Oat Lipid Extract derived from Avena sativa, comprising ‘skin identical’ ratios of fatty acids, ceramides and cholesterol/sterol. This investigation is the first reported investigation of oat lipids utilizing Raman spectroscopy for the ...
E. Gombert, C. Dewis
wiley +1 more source
The potential effect of albumin replacement on immune modulation and sphingosine 1-phosphate dynamics. [PDF]
Winkler MS +5 more
europepmc +1 more source
Clinical Significance of Plasma Sphingosine-1-Phosphate Decline in Progression of Spinal and Bulbar Muscular Atrophy. [PDF]
Jung YH +6 more
europepmc +1 more source
Pharmacological blockade of G-protein coupled receptors : interventions to alter expression or internalization [PDF]
Hangartner, Christoph
core +1 more source
Pan-cancer signaling landscape linked to endothelial and immune Sphingosine-1-phosphate receptor 1 (S1PR1) expression. [PDF]
Torres-Santos Y +3 more
europepmc +1 more source

