Sphingosine-1-phosphate activation of TRPC5 in vascular smooth muscle cells [PDF]
, 2008 Samantha Fahy
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Inhibition of sphingosine-1-phosphate receptor 3 suppresses ATP-induced NLRP3 inflammasome activation in macrophages via TWIK2-mediated potassium efflux [PDF]
, 2023 Yingqin Wang +6 more
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Pouch Surgery for Ulcerative Colitis: Navigating Complexity in the Modern Era
JCC Plus, Volume 1, Issue 3, May 2026.ABSTRACT Restorative proctocolectomy with ileal pouch–anal anastomosis (IPAA) remains the preferred surgical treatment for patients with ulcerative colitis (UC) who require surgery but wish to avoid a permanent ileostomy. Since its introduction in 1978, IPAA has undergone continuous refinement in response to advances in both medical therapy and ...
Gabriele Bislenghi +4 more
wiley +1 more source
Innate Lymphoid Cells in Tissue Homeostasis and Diseases
MedComm, Volume 7, Issue 5, May 2026.Innate lymphoid cells (ILCs) are a heterogeneous group of immune cells with phenotypic and functional plasticity. ILCs dynamically regulate various immune cell types and play a crucial role in the pathophysiological processes of specific organs during sepsis. Targeting ILCs is a promising strategy for treating sepsis.
Zhenzhen Zhan +7 more
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Clinical and Translational Science, Volume 19, Issue 5, May 2026.ABSTRACT Reliable biomarkers that enable noninvasive, longitudinal assessment of disease activity and therapeutic response remain a major unmet need in inflammatory bowel disease (IBD). While colonic biopsies are the gold standard for evaluating mucosal inflammation, their invasive nature and limited spatial and temporal resolution constrain their ...
Mohamed Hassanein +8 more
wiley +1 more source
Sphingosine‐1‐phosphate receptor 1 mediates elevated IL‐6 signaling to promote chronic inflammation and multitissue damage in sickle cell disease [PDF]
, 2018 Shushan Zhao +8 more
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From Development to Aging: Dynamic Roles of the Thymic Medulla in T Cell Biology
Immunological Reviews, Volume 339, Issue 1, May 2026.ABSTRACT The thymic medulla is essential for establishing central tolerance, orchestrating the development of a diverse yet self‐tolerant T cell repertoire, and preventing autoimmunity. This process is primarily mediated through interactions between developing thymocytes and antigen‐presenting cells, including thymic epithelial cells (TECs) and ...
Christina Michalaki +2 more
wiley +1 more source
Orthopedic Center of Chinese PLA, Urumqi General Hospital of Lanzhou Military Region, [PDF]
Sphingosine-1-phosphate is a possible fibrogenic factor in ...
Chenguang Zhao +5 more
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The effect of resistance training on plasma and skeletal muscles sphingosine-1-phosphate levels of male Wistar rat [PDF]
, 2012 زمینه و هدف: اسفنگوزین-1-فسفات (S1P) یک اسفنگولیپید بیواکتیو مشتق شده از پلاکت ها می باشد که در تنظیم تکثیر، تمایز، هایپرتروفی و مقابله با مرگ برنامه ریزی شده سلولی و فعال سازی سلول های ماهواره ای درگیر می باشد.
Banitalebi, Ebrahim. +4 more
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