Results 151 to 160 of about 526,512 (229)

The molecular mechanism of sphingosine kinase activation

Many cell processes like growth, death and differentiation are controlled by hormones and other molecules that interact with receptors on the outside of the cell.

core  

Discovery of Sphingosine Kinase Inhibition by Modified Quinoline-5,8-Diones. [PDF]

Pharmaceuticals (Basel)
Kruschel RD, Malone K, Walsh AN, Waeber C, McCarthy FO.   +4 more
europepmc   +1 more source

Upregulated <i>BLM</i> and <i>RECQL4</i> in Osteosarcoma: Association with Poor Prognosis, Immune Cell Infiltration, and Inhibitory Effects of Sphingosine Kinase 1 Inhibitor II/Pilaralisib. [PDF]

Immunotargets Ther
Chen J, Situ Y, Cai J, Liao W, Jiang D, Huang C, Zheng J, Peng L, Lin H.   +8 more
europepmc   +1 more source

Sphingosine kinase 2 regulates insulin receptor trafficking in hepatocytes. [PDF]

Exp Biol Med (Maywood), 2023
Aji G, Jiang S, Obulkasim H, Lu Z, Wang W, Xia P.   +5 more
europepmc   +1 more source

Exploring anticancer activity of baicalin, naringenin, and noscapine via binding and inhibition of sphingosine kinase 1. [PDF]

3 Biotech
Shakeel I, Mohammad T, Haider S, Hussain A, AlAjmi MF, Chakrabarty A, Sohal SS, Afzal M, Hassan MI.   +8 more
europepmc   +1 more source

Study on the CHJ01 antitumor activity and mechanism via targeting sphingosine kinase 1 in A549 cells. [PDF]

Pharm Sci Adv
Liu C, Gao S, Liu B, Zhang F, Mu Y, Wang F, Li Y.   +6 more
europepmc   +1 more source

Sphingosine kinase 1 inhibition aggravates vascular smooth muscle cell calcification. [PDF]

Pflugers Arch
Razazian M, Bahiraii S, Jannat I, Tiffner A, Beilhack G, Levkau B, Voelkl J, Alesutan I.   +7 more
europepmc   +1 more source

Sphingosine kinase 1 facilitates gastric cancer progression via <i>STAT1</i> gene methylation-mediated mechanisms. [PDF]

Transl Cancer Res
Wang Y, Wang F, Zhou B, Lu J, Xie J, Yuan L, Han S.   +6 more
europepmc   +1 more source

Identification of Sphingosine Kinase 1 as a Novel Protein Regulated by High Molecular Weight Hyaluronan in Ovarian Cancer. [PDF]

J Cell Mol Med
Price ZK, Lokman NA, Morrison J, Mhlanga SN, Sugiyama M, Koya Y, Davies LT, Pitson SM, Oehler MK, Pitman MR, Yoshihara M, Kajiyama H, Ricciardelli C.   +12 more
europepmc   +1 more source

Sphingosine kinase 2 deficiency impairs VLDL secretion by inhibiting mTORC2 phosphorylation and activating chaperone-mediated autophagy. [PDF]

Cell Death Differ
Zhang S, Li G, He L, Wang F, Gao M, Dai T, Su Y, Li L, Cao Y, Zheng M, Chen L, Cao J, Zhou H.   +12 more
europepmc   +1 more source