Spider-Venom Peptides: Structure, Bioactivity, Strategy, and Research Applications [PDF]
Molecules, 2023 Spiders (Araneae), having thrived for over 300 million years, exhibit remarkable diversity, with 47,000 described species and an estimated 150,000 species in existence. Evolving with intricate venom, spiders are nature’s skilled predators.
Ruiyin Guo +5 more
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Genomic and transcriptomic analyses support a silk gland origin of spider venom glands [PDF]
BMC Biology, 2023 Background Spiders comprise a hyperdiverse lineage of predators with venom systems, yet the origin of functionally novel spider venom glands remains unclear.
Bingyue Zhu +5 more
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Toxicological Characterization and Phospholipase D Activity of the Venom of the Spider Sicarius thomisoides [PDF]
Toxins, 2020 Envenomation by Loxosceles spiders (Sicariidae family) has been thoroughly documented. However, little is known about the potential toxicity of members from the Sicarius genus.
Tomás Arán-Sekul +7 more
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Enlightening the toxinological dark matter of spider venom enzymes [PDF]
npj BiodiversitySpiders produce highly adapted venoms featuring a complex mixture of biomolecules used mainly for hunting and defense. The most prominent components are peptidic neurotoxins, a major focus of research and drug development, whereas venom enzymes have been
Josephine Dresler +3 more
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A Proteomics and Transcriptomics Investigation of the Venom from the Barychelid Spider Trittame loki (Brush-Foot Trapdoor) [PDF]
Toxins, 2013 Although known for their potent venom and ability to prey upon both invertebrate and vertebrate species, the Barychelidae spider family has been entirely neglected by toxinologists. In striking contrast, the sister family Theraphosidae (commonly known as
Eivind A. B. Undheim +12 more
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Venomous spiders of Albania -does an increase of temperature influence the toxicity of spider venom? [PDF]
Toxicon X, 2022 Black widow spiders (Latrodectus sp.) are distributed worldwide, and in Albania the L. tredecimguttatus Rossi, 1790 has been the dominant spider. Other medically important spiders in Albania include the brown recluse with symptoms known as loxoscelism, the false black widow and the egg sac spiders; the last two inducing similar symptoms to a wasp sting.
Vrenozi, Blerina.
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Toxicon: X, 2020 Spiders use their venom for defence and to capture prey. These venoms contain a cocktail of biologically active compounds that display several different biological activities, such as large molecules and small molecules including peptides, proteins ...
Pornsawan Khamtorn +6 more
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Phlogiellus bundokalbo spider venom: cytotoxic fractions against human lung adenocarcinoma (A549) cells [PDF]
Journal of Venomous Animals and Toxins including Tropical Diseases, 2020 Background: Spider venom is a potential source of pharmacologically important compounds. Previous studies on spider venoms reported the presence of bioactive molecules that possess cell-modulating activities.
Anna Beatriz R. Mayor +3 more
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Prospects and challenges of recombinant spider venom enzymes: insights from Loxosceles and Phoneutria venom protease expressions [PDF]
Frontiers in Bioengineering and BiotechnologySpiders use chemically complex venoms to overpower prey. Such venoms are primarily composed of neurotoxic disulfide-rich peptides, linear peptides, and enzymes.
Josephine Dresler +11 more
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Can we resolve the taxonomic bias in spider venom research? [PDF]
Toxicon: X, 2019 The rate of discovery of new spider species greatly exceeds the rate of spider venom characterisation, leading to an increasing number of species with unstudied venoms.
Volker Herzig +2 more
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