Origin and Characterization of Extracellular Vesicles Present in the Spider Venom of Ornithoctonus hainana. [PDF]
Toxins (Basel), 2021 Extracellular vesicles (EVs), including exosomes and microvesicles, are membranous vesicles released from nearly all cellular types. They contain various bioactive molecules, and their molecular composition varies depending on their cellular origin.
Xun C +8 more
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Selective Targeting of Nav1.7 with Engineered Spider Venom-Based Peptides. [PDF]
Channels (Austin), 2021 A fundamental mechanism that drives the propagation of electrical signals in the nervous system is the activation of voltage-gated sodium channels. The sodium channel subtype Nav1.7 is critical for the transmission of pain-related signaling, with gain-of-
Neff RA, Wickenden AD.
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Frontiers in Molecular Biosciences, 2023 Introduction: Spider venoms are a unique source of bioactive peptides, many of which display remarkable biological stability and neuroactivity. Phoneutria nigriventer, often referred to as the Brazilian wandering spider, banana spider or “armed” spider ...
F. C. Cardoso +6 more
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Venomous spiders of Albania -does an increase of temperature influence the toxicity of spider venom? [PDF]
Toxicon X, 2022 Black widow spiders (Latrodectus sp.) are distributed worldwide, and in Albania the L. tredecimguttatus Rossi, 1790 has been the dominant spider. Other medically important spiders in Albania include the brown recluse with symptoms known as loxoscelism, the false black widow and the egg sac spiders; the last two inducing similar symptoms to a wasp sting.
Vrenozi, Blerina.
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Brown spider venom toxins: what are the functions of astacins, serine proteases, hyaluronidases, allergens, TCTP, serpins and knottins? [PDF]
J Venom Anim Toxins Incl Trop Dis, 2021 Accidents caused by the bites of brown spiders (Loxosceles) generate a clinical condition that often includes a threatening necrotic skin lesion near the bite site along with a remarkable inflammatory response.
Gremski LH +10 more
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VenoMS—A Website for the Low Molecular Mass Compounds in Spider Venoms [PDF]
Metabolites, 2020 Spider venoms are highly complex mixtures. Numerous spider venom metabolites are uniquely found in spider venoms and are of interest concerning their potential use in pharmacology, agriculture, and cosmetics.
Yvonne M. Forster +4 more
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Forty Years of the Description of Brown Spider Venom Phospholipases-D. [PDF]
Toxins (Basel), 2020 Spiders of the genus Loxosceles, popularly known as Brown spiders, are considered a serious public health issue, especially in regions of hot or temperate climates, such as parts of North and South America.
Gremski LH +9 more
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Frontiers in Arachnid ScienceSpiders are ancient and highly successful predators, which use venom for both predation and defense. Their venoms are complex mixtures of potent biological molecules, emerging as a prolific source of biomolecular innovation in agriculture, biomedicine ...
Josephine Dresler +14 more
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Phlogiellus bundokalbo spider venom: cytotoxic fractions against human lung adenocarcinoma (A549) cells [PDF]
Journal of Venomous Animals and Toxins including Tropical Diseases, 2020 Background: Spider venom is a potential source of pharmacologically important compounds. Previous studies on spider venoms reported the presence of bioactive molecules that possess cell-modulating activities.
Anna Beatriz R. Mayor +3 more
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LCTX-F2, a Novel Potentiator of Coagulation Factors From the Spider Venom of Lycosa singoriensis. [PDF]
Front Pharmacol, 2020 Spider venoms contain many functional proteins/peptides such as proteinases, serine/cysteine proteinase inhibitors, insecticidal toxins, and ion channel toxins.
Li P +6 more
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