ABSTRACT Fluorouracil‐platinum(IV) prodrugs represent a novel class of multimechanistic chemotherapeutics with enhanced anticancer potential. The prodrugs PtIVP‐5FUMeOBut and PtIV56‐5FUMeOBut were actualized by derivatising the clinical drug 5‐fluorouracil (5FU) and coordinating it to platinum(IV) complexes, leveraging the established cytotoxicity of ...
Maria George Elias +9 more
wiley +1 more source
Polarity-dependent modulation of sleep oscillations and cortical excitability in aging. [PDF]
Dikici B +5 more
europepmc +1 more source
Revisiting the synthesis of dimethyl carbonate from methanol and carbon dioxide
Abstract The process for producing dimethyl carbonate (DMC) from carbon dioxide (CO2) and methanol is explored in this article. It provides an overview of the thermodynamics involved in DMC synthesis, discussing the challenges and potential solutions. The article highlights the reported use of catalysts and dehydrating agents to improve DMC yield and ...
Diego Alexander Santos Araque +3 more
wiley +1 more source
Interaction Between Actin and Microtubules During Plant Development
ABSTRACT The dynamic interaction between actin filaments (AFs) and microtubules (MTs) plays a crucial role in regulating key developmental and physiological processes in plant cells, particularly in the formation of specialized cell types with distinct shapes and functions, such as pollen tubes, trichomes, and leaf epidermal cells.
Zining Wu +3 more
wiley +1 more source
Red Bumps, Red Flags: A Case Series of Four Neoplasms Masquerading as Inflamed Cutaneous Cysts. [PDF]
Hensley J +4 more
europepmc +1 more source
PEK14: A Kinesin‐4 Necessary for Male‐Derived Fertility in Arabidopsis thaliana
ABSTRACT Of the 61 kinesins annotated in Arabidopsis thaliana, many are still without assigned function. Here, we have screened an insertional mutant library of Arabidopsis pollen‐expressed kinesins for fertility defects. Insertional mutants for three kinesins showed a significant reduction in seed set.
Isabella N. Mendes +6 more
wiley +1 more source
Primary small intestine angiofibroma of soft tissue (AFST) with intussusception: an extremely rare case report and review of literature. [PDF]
Liu M, Sun Y, Wang S, Jiang Z.
europepmc +1 more source
ABSTRACT Of the three types of cytoskeleton known in animals—actin, microtubules, and intermediate filaments—only actin and microtubules exist in plants. Both play important roles in cellular shaping, organelle movement, organization of the endomembrane system, and cell signaling.
Norman R. Groves +3 more
wiley +1 more source
Case Report: Reconstruction of the chest wall with titanium alloy plates after resection of a rare malignant spindle cell tumor of the sternum complicated by ankylosing spondylitis. [PDF]
Wang X, Zhu P, Zhang Y.
europepmc +1 more source

