Results 31 to 40 of about 39,110 (117)

Pericentric major satellite transcription is essential for meiotic chromosome stability and spindle pole organization

Open Biology, 2023
In somatic cells, mitotic transcription of major satellite non-coding RNAs is tightly regulated and essential for heterochromatin formation and the maintenance of genome integrity.
Claudia Baumann, Xiangyu Zhang, Maria M. Viveiros, Rabindranath De La Fuente   +3 more
doaj   +1 more source

Measurement of Spindle Rigidity by using a Magnet Loader

Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2010
The static rigidity of a rotating spindle in the radial direction is investigated in this research. A magnetic loading device (magnet loader) has been developed for the measurement.
Taku YAMAZAKI, Atsushi MATSUBARA, Tomoya FUJITA, Toshiyuki MURAKI, Kohei ASANO, Kazuyuki KAWASHIMA   +5 more
doaj   +1 more source

Emerging Insights into the Function of Kinesin-8 Proteins in Microtubule Length Regulation

Biomolecules, 2018
Proper regulation of microtubules (MTs) is critical for the execution of diverse cellular processes, including mitotic spindle assembly and chromosome segregation.
Sanjay Shrestha, Mark Hazelbaker, Amber L. Yount, Claire E. Walczak   +3 more
doaj   +1 more source

Research on a Power Management System for Thermoelectric Generators to Drive Wireless Sensors on a Spindle Unit

Sensors, 2014
Thermoelectric energy harvesting is emerging as a promising alternative energy source to drive wireless sensors in mechanical systems. Typically, the waste heat from spindle units in machine tools creates potential for thermoelectric generation. However,
Sheng Li, Xinhua Yao, Jianzhong Fu
doaj   +1 more source

Method for Vibration Response Simulation and Sensor Placement Optimization of a Machine Tool Spindle System with a Bearing Defect

Sensors, 2012
Bearing defects are one of the most important mechanical sources for vibration and noise generation in machine tool spindles. In this study, an integrated finite element (FE) model is proposed to predict the vibration responses of a spindle bearing ...
Hongrui Cao, Linkai Niu, Zhengjia He
doaj   +1 more source

Early onset of APC/C activity renders SAC inefficient in mouse embryos

Frontiers in Cell and Developmental Biology
Control mechanisms of spindle assembly and chromosome segregation are vital for preventing aneuploidy during cell division. The mammalian germ cells and embryos are prone to chromosome segregation errors, and the resulting aneuploidy is a major cause of ...
Adela Horakova, Adela Horakova, Adela Horakova, Marketa Konecna, Marketa Konecna, Marketa Konecna, Lenka Radonova, Lenka Radonova, Martin Anger, Martin Anger   +9 more
doaj   +1 more source

Practical Estimation of Machine Tool Spindle Dynamics for Maintenance Decision Making

Applied Sciences
Condition-based maintenance of a machine tool spindle unit is known to reduce the total cost of operation in a manufacturing environment. However, standard vibration monitoring thresholds, which are based only on average vibration energy levels, do not ...
Patrick Chin, Jose M. DePavia, Stephen C. Veldhuis   +2 more
doaj   +1 more source

Spindle assembly checkpoint-dependent mitotic delay is required for cell division in absence of centrosomes

eLife
The spindle assembly checkpoint (SAC) temporally regulates mitosis by preventing progression from metaphase to anaphase until all chromosomes are correctly attached to the mitotic spindle.
KC Farrell, Jennifer T Wang, Tim Stearns
doaj   +1 more source

Recent advances in plant kinetochore research

Frontiers in Cell and Developmental Biology
Faithful chromosome segregation is crucial for cell division in eukaryotes, facilitated by the kinetochore, a multi-subunit protein complex that connects chromosomes to the spindle microtubules.
Elena Kozgunova, Elena Kozgunova
doaj   +1 more source

The equatorial position of the metaphase plate ensures symmetric cell divisions

eLife, 2015
Chromosome alignment in the middle of the bipolar spindle is a hallmark of metazoan cell divisions. When we offset the metaphase plate position by creating an asymmetric centriole distribution on each pole, we find that metaphase plates relocate to the ...
Chia Huei Tan, Ivana Gasic, Sabina P Huber-Reggi, Damian Dudka, Marin Barisic, Helder Maiato, Patrick Meraldi   +6 more
doaj   +1 more source