Results 31 to 40 of about 562,858 (399)

Mitotic Acetylation of Microtubules Promotes Centrosomal PLK1 Recruitment and Is Required to Maintain Bipolar Spindle Homeostasis

Cells, 2021
Tubulin post-translational modifications regulate microtubule properties and functions. Mitotic spindle microtubules are highly modified. While tubulin detyrosination promotes proper mitotic progression by recruiting specific microtubule-associated ...
Sylvia Fenosoa Rasamizafy, Claude Delsert, Gabriel Rabeharivelo, Julien Cau, Nathalie Morin, Juliette van Dijk   +5 more
doaj   +1 more source

The Development of a Monitoring System Using a Wireless and Powerless Sensing Node Deployed Inside a Spindle

Sensors, 2011
Installation of a Wireless and Powerless Sensing Node (WPSN) inside a spindle enables the direct transmission of monitoring signals through a metal case of a certain thickness instead of the traditional method of using connecting cables.
Da-Sheng Lee, Liang-Cheng Chang
doaj   +1 more source

Spindle Starshaped Sets [PDF]

, 2014
In this paper, spindle starshaped sets are introduced and investigated, which apart from normalization form an everywhere dense subfamily within the family of starshaped sets. We focus on proving spindle starshaped analogues of recent theorems of Bobylev,
Bezdek, Karoly, Naszodi, Marton
core   +2 more sources

Dual-spindle formation in zygotes keeps parental genomes apart in early mammalian embryos

Science, 2018
It takes two to tango Fusion of egg and sperm combines the genetic material of both parents in one cell. In mammals, including humans, each parental genome is initially confined in a separate pronucleus.
Judith Reichmann, B. Nijmeijer, M. J. Hossain, M. Eguren, I. Schneider, A. Politi, M. Roberti, L. Hufnagel, T. Hiiragi, J. Ellenberg   +9 more
semanticscholar   +1 more source

Regulation of Op18 during Spindle Assembly in Xenopus Egg Extracts [PDF]

, 2001
Oncoprotein 18 (Op18) is a microtubule-destabilizing protein that is negatively regulated by phosphorylation. To evaluate the role of the three Op18 phosphorylation sites in Xenopus (Ser 16, 25, and 39), we added wild-type Op18, a nonphosphorylatable ...
Andersen, Andersen, Arnaud, Bahler, Belmont, Brattsand, Carmena, Cassimeris, Charles, Curmi, Curmi, Desai, Desai, Descombes, Di Paolo, Felix, Gard, Gavet, Gigant, Glover, Golsteyn, Gruss, Hamanaka, Heald, Heald, Heald, Heald, Hirano, Horwitz, Howell, Howell, Hyman, Jourdain, Karaiskou, Kotani, Kumagai, Kumagai, Lane, Larsson, Lawler, Llamazares, Logarinho, Luo, Marklund, Maucuer, McKim, Moutinho-Santos, Murray, Nachury, Nigg, Ohkura, Qian, Qian, Sandaltzopoulos, Sawin, Schubart, Shirayama, Steinmetz, Sunkel, Taagepera, Tournebize, Vernos, Walczak, Wallon, Wianny, Wiese, Wray, Zhang   +67 more
core   +4 more sources

Spindle asymmetry drives non-Mendelian chromosome segregation

Science, 2017
How selfish genes get their way At the core of Mendelian genetics is the concept that gametes are equally likely to carry either of the two parental copies of a gene.
Takashi Akera, Lukas Chmatal, Emily Trimm, Karren Yang, Chanat Aonbangkhen, D. Chenoweth, C. Janke, R. Schultz, M. Lampson   +8 more
semanticscholar   +1 more source

NuMA recruits dynein activity to microtubule minus-ends at mitosis

eLife, 2017
To build the spindle at mitosis, motors exert spatially regulated forces on microtubules. We know that dynein pulls on mammalian spindle microtubule minus-ends, and this localized activity at ends is predicted to allow dynein to cluster microtubules into
Christina L Hueschen, Samuel J Kenny, Ke Xu, Sophie Dumont   +3 more
doaj   +1 more source

Practical Estimation of Machine Tool Spindle Dynamics for Maintenance Decision Making

Applied Sciences
Condition-based maintenance of a machine tool spindle unit is known to reduce the total cost of operation in a manufacturing environment. However, standard vibration monitoring thresholds, which are based only on average vibration energy levels, do not ...
Patrick Chin, Jose M. DePavia, Stephen C. Veldhuis   +2 more
doaj   +1 more source

Live cell imaging of meiosis in Arabidopsis thaliana

eLife, 2019
To follow the dynamics of meiosis in the model plant Arabidopsis, we have established a live cell imaging setup to observe male meiocytes. Our method is based on the concomitant visualization of microtubules (MTs) and a meiotic cohesin subunit that ...
Maria A Prusicki, Emma M Keizer, Rik P van Rosmalen, Shinichiro Komaki, Felix Seifert, Katja Müller, Erik Wijnker, Christian Fleck, Arp Schnittger   +8 more
doaj   +1 more source

TRIP13PCH-2 promotes Mad2 localization to unattached kinetochores in the spindle checkpoint response. [PDF]

, 2015
The spindle checkpoint acts during cell division to prevent aneuploidy, a hallmark of cancer. During checkpoint activation, Mad1 recruits Mad2 to kinetochores to generate a signal that delays anaphase onset.
Bhalla, Needhi, Chen, Pin-Hsi, Hwang, Tom, Nelson, Christian R   +3 more
core   +1 more source