Results 31 to 40 of about 542,273 (348)
Generation and diversification of recombinant monoclonal antibodies
eLife, 2021 Antibodies are indispensable tools used for a large number of applications in both foundational and translational bioscience research; however, there are drawbacks to using traditional antibodies generated in animals.
Keith F DeLuca +11 more
doaj +1 more source
A liquid-like spindle domain promotes acentrosomal spindle assembly in mammalian oocytes
Science, 2019 A new phase in egg biology Chromosome segregation typically requires centrosomes, which generate the microtubule spindle. However, mammalian eggs build a spindle and segregate chromosomes without centrosomes.
C. So +7 more
semanticscholar +1 more source
Retroperitoneal spindle cell variant of embryonal rhabdomyosarcoma in a child
Medical Journal of Dr. D.Y. Patil Vidyapeeth, 2019 Spindle cell rhabdomyosarcoma (RMS) is a rare variant of embryonal RMS that has a predilection for young males and most commonly involves the paratesticular region followed by the head and neck.
Aditya Pratap Singh +3 more
doaj +1 more source
Excess TPX2 Interferes with Microtubule Disassembly and Nuclei Reformation at Mitotic Exit
Cells, 2020 The microtubule-associated protein TPX2 is a key mitotic regulator that contributes through distinct pathways to spindle assembly. A well-characterised function of TPX2 is the activation, stabilisation and spindle localisation of the Aurora-A kinase ...
Francesco D. Naso +9 more
doaj +1 more source
A sleep spindle detection algorithm that emulates human expert spindle scoring.
Journal of Neuroscience Methods, 2019 BACKGROUND Sleep spindles are a marker of stage 2 NREM sleep that are linked to learning & memory and are altered by many neurological diseases. Although visual inspection of the EEG is considered the gold standard for spindle detection, it is time ...
K. Lacourse +4 more
semanticscholar +1 more source
PASSIVE TORQUE SIMULATION OF SMALL ANGULAR CONTACT BEARING AT HIGH SPEED [PDF]
, 2017 Description of common ball bearing torque models was presented and adopted to the complex thermo-mechanical model of the high speed spindle. Ball bearing passive torque was measured on the own high-speed spindle design.
Kekula J., Smolík J., Sulitka M.
core +1 more source
Sleep spindle refractoriness segregates periods of memory reactivation
bioRxiv, 2017 The stability of long-term memories is enhanced by reactivation during sleep. Correlative evidence has linked memory reactivation with thalamocortical sleep spindles, although their functional role is poorly understood.
J. Antony +5 more
semanticscholar +1 more source
Cells, 2021 Tubulin post-translational modifications regulate microtubule properties and functions. Mitotic spindle microtubules are highly modified. While tubulin detyrosination promotes proper mitotic progression by recruiting specific microtubule-associated ...
Sylvia Fenosoa Rasamizafy +5 more
doaj +1 more source
, 2016 Anaphase B spindle elongation is characterized by the sliding apart of overlapping antiparallel interpolar (ip) microtubules (MTs) as the two opposite spindle poles separate, pulling along disjoined sister chromatids, thereby contributing to chromosome ...
Brust-Mascher, Ingrid +2 more
core +2 more sources
Memory Consolidation Is Linked to Spindle-Mediated Information Processing during Sleep
bioRxiv, 2017 How are brief encounters transformed into lasting memories? Previous research has established the role of non-rapid eye movement (NREM) sleep, along with its electrophysiological signatures of slow oscillations (SOs) and spindles, for memory ...
Scott A. Cairney +3 more
semanticscholar +1 more source