The novel BTB-kelch protein, KBTBD8, is located in the Golgi apparatus and translocates to the spindle apparatus during mitosis [PDF]
Cell Division, 2013 Proteins of the BTB-kelch family are known to be involved in multiple biological processes such as migration, cytoskeleton arrangement, regulation of cell morphology, protein ubiquitination and gene expression. KBTBD8 is a new member of this family.
Sandra Lührig +3 more
semanticscholar +6 more sources
Autoantibodies to the mitotic spindle apparatus in Mycoplasma pneumoniae disease [PDF]
Infection and Immunity, 1988 Antibodies to the mitotic spindle apparatus (MS) have been detected in only a very few patient sera studied for antinuclear antibodies by routine screening (G. A. McCarty, D. W. Velencia, and M. J. Fritzler, J. Rheumatol. 11:213-218, 1984). We found anti-MS antibodies to be quite common in sera from patients with Mycoplasma pneumoniae, especially in ...
K Lind, Mimi Høier‐Madsen, Allan Wiik
semanticscholar +4 more sources
Nuclear Mitotic Apparatus (NuMA) Interacts with and Regulates Astrin at the Mitotic Spindle [PDF]
Journal of Biological Chemistry, 2016 The large nuclear mitotic apparatus (NuMA) protein is an essential player in mitotic spindle assembly and maintenance. We report here the identification of Astrin, a spindle- and kinetochore-associated protein, as a novel interactor of NuMA. We show that the C-terminal tail of NuMA can directly bind to the C terminus of Astrin and that this interaction
Xiaogang Chu +4 more
semanticscholar +5 more sources
A case of oculomotor nerve palsy associated with antimitotic spindle apparatus
Clinical Ophthalmology, 2011 Jong Jin Jung, Ungsoo Samuel KimDepartment of Ophthalmology, Kim's Eye Hospital, Konyang University College of Medicine, Seoul, KoreaAbstract: In this case report, we describe a case of isolated oculomotor nerve palsy associated with antibodies ...
Kim US, Jung JJ
doaj +5 more sources
Antibodies to Mitotic Spindle Apparatus: Clinical Significance of NuMA and HsEg5 Autoantibodies
Journal of Clinical Immunology, 2008 The clinical associations of NuMA and HsEg5 antibodies, the main anti-mitotic spindle apparatus autoantibodies, remain unclear due to their extremely low prevalence.We have analysed the clinical data of 40 anti-NuMA- (0.87 per thousand) and 7 anti-HsEg5- (0.15 per thousand) positive patients detected during routine immunofluorescence examination of 45 ...
Lourdes Mozo +2 more
semanticscholar +5 more sources
MAD2 Combined with Mitotic Spindle Apparatus (MSA) and Anticentromere Antibody (ACA) for Diagnosis of Small Cell Lung Cancer (SCLC). [PDF]
Med Sci Monit, 2018 Background MAD2 is the gene controlling mitosis. Many studies have assessed MAD2 in various types of carcinoma. Antinuclear mitotic spindle apparatus antibody (MSA) and anticentromere antibody (ACA) are related mitotic antibodies, playing roles in ...
Wu Y +12 more
europepmc +2 more sources
Transforming Acidic Coiled-coil-containing Protein 4 Interacts with Centrosomal AKAP350 and the Mitotic Spindle Apparatus [PDF]
Journal of Biological Chemistry, 2002 AKAP350 is a multiply spliced family of 350–450-kDa protein kinase A-anchoring proteins localized to the centrosomes and the Golgi apparatus. Using AKAP350A as bait in a yeast two-hybrid screen of a rabbit parietal cell library, we have identified a ...
Brent T. Steadman +4 more
openalex +2 more sources
Intermediate Filament Protein BFSP2 Controls Spindle Formation via HSC70‐Mediated Stabilization of CLTC During Oocyte meiosis [PDF]
Advanced ScienceAs a major component of the cytoskeleton, intermediate filaments are generally considered to play a supporting role in mitotic cells. They also take part in the regulation of cell motility, proliferation, differentiation, and apoptosis.
Yu Li, Zihao Zhang, Yu Zhang, Bo Xiong
doaj +2 more sources
Identification of a 52-kD calmodulin-binding protein associated with the mitotic spindle apparatus in mammalian cells. [PDF]
Journal of Cell Biology, 1986 A pool of 10 calmodulin-binding proteins (CBPs) was isolated from Chinese hamster ovary (CHO) cells via calmodulin (CaM)-Sepharose affinity chromatography.
Richard C. Brady +2 more
openalex +2 more sources
Spindle birefringence of isolated mitotic apparatus: further evidence for two birefringent spindle components [PDF]
Journal of Cell Science, 1976 ABSTRACT We studied sea-urchin zygote mitotic apparatus (MA) isolated in hexylene glycol, transferred immediately to a glycerol-dimethylsulphoxide medium, and stored for 2 weeks at room temperature. Treatment with 0·5 M KC1 caused loss of 45% of the birefringence, but microtubules remained intact (as seen electron microscopically in ...
Arthur Forer +2 more
openalex +3 more sources