INTERMICROTUBULE BRIDGES IN MITOTIC SPINDLE APPARATUS [PDF]
Journal of Cell Biology, 1970 Fine interconnections or "cross-bridges" have been observed between cytoplasmic microtubules in many different organisms (1, 3, 7, 9, 10, 12, 13) . Recently, similar bridges have been noted between the microtubules of the spindle apparatus in dividing ...
Peter K. Hepler +2 more
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The Nuclear Mitotic Apparatus (NuMA) Protein: A Key Player for Nuclear Formation, Spindle Assembly, and Spindle Positioning [PDF]
Frontiers in Cell and Developmental Biology, 2021 The nuclear mitotic apparatus (NuMA) protein is well conserved in vertebrates, and dynamically changes its subcellular localization from the interphase nucleus to the mitotic/meiotic spindle poles and the mitotic cell cortex.
Tomomi Kiyomitsu, Susan Boerner
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The nuclear-mitotic apparatus protein is important in the establishment and maintenance of the bipolar mitotic spindle apparatus. [PDF]
Molecular Biology of the Cell, 1992 The formation and maintenance of the bipolar mitotic spindle apparatus require a complex and balanced interplay of several mechanisms, including the stabilization and separation of polar microtubules and the action of various microtubule motors ...
Chao Yang, M Snyder
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Transforming Acidic Coiled-coil-containing Protein 4 Interacts with Centrosomal AKAP350 and the Mitotic Spindle Apparatus [PDF]
Journal of Biological Chemistry, 2002 AKAP350 is a multiply spliced family of 350–450-kDa protein kinase A-anchoring proteins localized to the centrosomes and the Golgi apparatus. Using AKAP350A as bait in a yeast two-hybrid screen of a rabbit parietal cell library, we have identified a ...
Brent T. Steadman +4 more
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Identification of a 52-kD calmodulin-binding protein associated with the mitotic spindle apparatus in mammalian cells. [PDF]
Journal of Cell Biology, 1986 A pool of 10 calmodulin-binding proteins (CBPs) was isolated from Chinese hamster ovary (CHO) cells via calmodulin (CaM)-Sepharose affinity chromatography.
Richard C. Brady +2 more
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Microtubules are the only structural constituent of the spindle apparatus required for induction of cell cleavage [PDF]
Journal of Cell Biology, 2003 Structural constituents of the spindle apparatus essential for cleavage induction remain undefined. Findings from various cell types using different approaches suggest the importance of all structural constituents, including asters, the central spindle ...
G. Bradley Alsop, Dahong Zhang
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LIN-5 Is a Novel Component of the Spindle Apparatus Required for Chromosome Segregation and Cleavage Plane Specification in Caenorhabditis elegans [PDF]
Journal of Cell Biology, 2000 Successful divisions of eukaryotic cells require accurate and coordinated cycles of DNA replication, spindle formation, chromosome segregation, and cytoplasmic cleavage.
Monique A. Lorson +2 more
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The centrosome and mitotic spindle apparatus in cancer and senescence [PDF]
Cell Cycle, 2010 Altered cell division is associated with overproliferation and tumorigenesis, however, mitotic aberrations can also trigger antiproliferative responses leading to postmitotic cell cycle exit. Here, we focus on the role of the centrosome and in particular
Stephan Schmidt +13 more
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Dynamic Localization of the Human Papillomavirus Type 11 Origin Binding Protein E2 through Mitosis While in Association with the Spindle Apparatus [PDF]
Journal of Virology, 2006 Papillomaviral DNA replicates as extrachromosomal plasmids in squamous epithelium. Viral DNA must segregate equitably into daughter cells to persist in dividing basal/parabasal cells.
Luan D. Dao +6 more
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The novel BTB-kelch protein, KBTBD8, is located in the Golgi apparatus and translocates to the spindle apparatus during mitosis [PDF]
Cell Division, 2013 Proteins of the BTB-kelch family are known to be involved in multiple biological processes such as migration, cytoskeleton arrangement, regulation of cell morphology, protein ubiquitination and gene expression. KBTBD8 is a new member of this family.
Sandra Lührig +3 more
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