Results 11 to 20 of about 59,120 (328)

INTERMICROTUBULE BRIDGES IN MITOTIC SPINDLE APPARATUS [PDF]

open access: bronzeThe Journal of Cell Biology, 1970
Peter K. Hepler   +2 more
openalex   +4 more sources

Spindle birefringence of isolated mitotic apparatus: further evidence for two birefringent spindle components [PDF]

open access: bronzeJournal of Cell Science, 1976
ABSTRACT We studied sea-urchin zygote mitotic apparatus (MA) isolated in hexylene glycol, transferred immediately to a glycerol-dimethylsulphoxide medium, and stored for 2 weeks at room temperature. Treatment with 0·5 M KC1 caused loss of 45% of the birefringence, but microtubules remained intact (as seen electron microscopically in ...
Arthur Forer   +2 more
openalex   +4 more sources

The centrosome and mitotic spindle apparatus in cancer and senescence [PDF]

open access: bronzeCell Cycle, 2010
Altered cell division is associated with overproliferation and tumorigenesis, however, mitotic aberrations can also trigger antiproliferative responses leading to postmitotic cell cycle exit. Here, we focus on the role of the centrosome and in particular of centrosomal TACC (transforming acidic coiled coil) proteins in tumorigenesis and cellular ...
Stephan Schmidt   +13 more
openalex   +4 more sources

Phase transition of spindle-associated protein regulate spindle apparatus assembly. [PDF]

open access: yesCell, 2015
Spindle assembly required during mitosis depends on microtubule polymerization. We demonstrate that the evolutionarily conserved low-complexity protein, BuGZ, undergoes phase transition or coacervation to promote assembly of both spindles and their associated components.
Jiang H   +6 more
europepmc   +5 more sources

The nuclear-mitotic apparatus protein is important in the establishment and maintenance of the bipolar mitotic spindle apparatus. [PDF]

open access: greenMolecular Biology of the Cell, 1992
The formation and maintenance of the bipolar mitotic spindle apparatus require a complex and balanced interplay of several mechanisms, including the stabilization and separation of polar microtubules and the action of various microtubule motors. Nonmicrotubule elements are also present throughout the spindle apparatus and have been proposed to provide
Chao Yang, M Snyder
openalex   +4 more sources

Manipulation of the oocyte: possible damage to the spindle apparatus

open access: bronzeReproductive BioMedicine Online, 2002
Oocytes are structured, polarized cells. For high developmental potential, it is essential that the distribution of organelles and molecules, and the function of meiotic spindles remain intact during handling of oocytes in assisted reproduction. Spindles are dynamic cell organelles. Spindle formation depends on activity of motor proteins, energy supply
Ursula Eichenlaub-Ritter   +2 more
openalex   +4 more sources

Rare Antinuclear Antibody Patterns: Relevance in Routine Laboratory Reporting [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2023
Introduction: Uncommon patterns on Human Epithelial 2 (Hep 2) substrate during Antinuclear Antibody (ANA) screening by Indirect Immunofluorescence (IIF) microscopy are not routinely reported by many laboratories since their clinical relevance is not well
Vidya Bhakta
doaj   +1 more source

Microtubules are the only structural constituent of the spindle apparatus required for induction of cell cleavage [PDF]

open access: bronzeThe Journal of Cell Biology, 2003
Structural constituents of the spindle apparatus essential for cleavage induction remain undefined. Findings from various cell types using different approaches suggest the importance of all structural constituents, including asters, the central spindle, and chromosomes. In this study, we systematically dissected the role of each constituent in cleavage
G. Bradley Alsop, Dahong Zhang
openalex   +3 more sources

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