LIN-5 Is a Novel Component of the Spindle Apparatus Required for Chromosome Segregation and Cleavage Plane Specification in Caenorhabditis elegans [PDF]
Journal of Cell Biology, 2000 Successful divisions of eukaryotic cells require accurate and coordinated cycles of DNA replication, spindle formation, chromosome segregation, and cytoplasmic cleavage.
Monique A. Lorson +2 more
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Microtubules are the only structural constituent of the spindle apparatus required for induction of cell cleavage [PDF]
Journal of Cell Biology, 2003 Structural constituents of the spindle apparatus essential for cleavage induction remain undefined. Findings from various cell types using different approaches suggest the importance of all structural constituents, including asters, the central spindle ...
G. Bradley Alsop, Dahong Zhang
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The nuclear-mitotic apparatus protein is important in the establishment and maintenance of the bipolar mitotic spindle apparatus. [PDF]
Molecular Biology of the Cell, 1992 The formation and maintenance of the bipolar mitotic spindle apparatus require a complex and balanced interplay of several mechanisms, including the stabilization and separation of polar microtubules and the action of various microtubule motors. Nonmicrotubule elements are also present throughout the spindle apparatus and have been proposed to provide
Charles H. YangandMichael Snyder
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Intermediate Filament Protein BFSP1 Maintains Oocyte Asymmetric Division by Modulating Spindle Length [PDF]
Advanced ScienceThe cytoskeleton is composed of microtubules, microfilaments, and intermediate filaments in cells. While the functions of microtubules and microfilaments have been well elucidated, the roles of intermediate filaments and associated proteins remain ...
Yu Li +6 more
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Spindle assembly defects leading to the formation of a monopolar mitotic apparatus [PDF]
Biology of the Cell, 2008 Mitotic spindle formation in animal cells involves microtubule nucleation from two centrosomes that are positioned at opposite sides of the nucleus. Microtubules are captured by the kinetochores and stabilized. In addition, microtubules can be nucleated independently of the centrosome and stabilized by a gradient of Ran—GTP, surrounding the mitotic ...
Vanessa Tillement +5 more
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Two major autoantigen-antibody systems of the mitotic spindle apparatus. [PDF]
Arthritis & Rheumatism, 1996 AbstractObjective. To characterize human autoantigen‐antibody systems related to the mitotic poles and spindles.Methods. Thirty‐seven human sera with autoantibodies staining mitotic poles and spindles in indirect immunofluorescence (IIF) studies were further characterized by immunofluorescence on mitotic cells and by immunoblotting and ...
Luis Eduardo Coelho Andrade +3 more
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Manipulation of the oocyte: possible damage to the spindle apparatus.
Reproductive BioMedicine Online, 2002 Oocytes are structured, polarized cells. For high developmental potential, it is essential that the distribution of organelles and molecules, and the function of meiotic spindles remain intact during handling of oocytes in assisted reproduction. Spindles are dynamic cell organelles. Spindle formation depends on activity of motor proteins, energy supply
U. Eichenlaub-Ritter +2 more
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Anti-Mitotic Spindle Apparatus Antoantibodies: Prevalence and Disease Association in Chinese Population. [PDF]
J Clin Lab Anal, 2016 Xi Q +6 more
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Microtubule capture by the cleavage apparatus is required for proper spindle positioning in yeast [PDF]
Genes & Development, 2002 Cell division is the result of two major cytoskeletal events: partition of the chromatids by the mitotic spindle and cleavage of the cell by the cytokinetic apparatus. Spatial coordination of these events ensures that each daughter cell inherits a nucleus. Here we show that, in budding yeast, capture and shrinkage of astral microtubules at the bud neck
Justine Kusch +3 more
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ASSOCIATION BETWEEN THE SPINDLE APPARATUS AND REOVIRUS. [PDF]
Proceedings of the National Academy of Sciences, 1963 S. Dales
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