Uncommon patterns of antinuclear antibodies recognizing mitotic spindle apparatus antigens and clinical associations. [PDF]
Medicine (Baltimore), 2018 Betancur JF +7 more
europepmc +2 more sources
Ethanolic Extract of Red Okra Pods Induces Aberrant Spindle Segregation and Apoptotic Cell Death by Disrupting the Wnt Signaling Pathway in Colon Cancer Cells [PDF]
Iranian Journal of Medical SciencesBackground: In approximately 80% of colorectal cancer cases, mutations in the adenomatous polyposis coli (APC) gene disrupt the Wingless-related integration site (Wnt)/β-catenin signaling pathway, a crucial factor in carcinogenesis.
Firli Rahmah Primula Dewi +4 more
doaj +2 more sources
The novel BTB-kelch protein, KBTBD8, is located in the Golgi apparatus and translocates to the spindle apparatus during mitosis [PDF]
Cell Division, 2013 Abstract Proteins of the BTB-kelch family are known to be involved in multiple biological processes such as migration, cytoskeleton arrangement, regulation of cell morphology, protein ubiquitination and gene expression. KBTBD8 is a new member of this family.
Sandra Lührig +3 more
openalex +6 more sources
Silencing of spindle apparatus coiled-coil protein 1 suppressed the progression of hepatocellular carcinoma through farnesyltransferase-beta and increased drug sensitivity. [PDF]
HeliyonZhai Y +10 more
europepmc +2 more sources
SCM-198 ameliorates the quality of postovulatory and maternally aged oocytes by reducing oxidative stress [PDF]
Journal of Ovarian ResearchOocyte aging is a key constraint on oocyte quality, leading to fertilization failure and abnormal embryonic development. In addition, it is likely to generate unfavorable assisted reproductive technology (ART) outcomes.
Wei Ma +7 more
doaj +2 more sources
Rare Antinuclear Antibody Patterns: Relevance in Routine Laboratory Reporting [PDF]
Journal of Clinical and Diagnostic Research, 2023 Introduction: Uncommon patterns on Human Epithelial 2 (Hep 2) substrate during Antinuclear Antibody (ANA) screening by Indirect Immunofluorescence (IIF) microscopy are not routinely reported by many laboratories since their clinical relevance is not well
Vidya Bhakta
doaj +1 more source
Evidence for spindle apparatus in somatic nuclei
Fungal Genetics Reports, 1971 W. B. Van Winkle
openalex +4 more sources
A nuclear-derived proteinaceous matrix embeds the microtubule spindle apparatus during mitosis
Molecular Biology of the Cell, 2012 The concept of a spindle matrix has long been proposed. Whether such a structure exists, however, and what its molecular and structural composition are have remained controversial. In this study, using a live-imaging approach in Drosophila syncytial embryos, we demonstrate that nuclear proteins reorganize during mitosis to form a highly dynamic ...
Changfu Yao +6 more
openalex +5 more sources
A Balance between Nuclear and Cytoplasmic Volumes Controls Spindle Length. [PDF]
PLoS ONE, 2016 Proper assembly of the spindle apparatus is crucially important for faithful chromosome segregation during anaphase. Thanks to the effort over the last decades, we have very detailed information about many events leading to spindle assembly and ...
Lucia Novakova +5 more
doaj +1 more source
USP11 deubiquitinates RAE1 and plays a key role in bipolar spindle formation. [PDF]
PLoS ONE, 2018 Correct segregation of the mitotic chromosomes into daughter cells is a highly regulated process critical to safeguard genome stability. During M phase the spindle assembly checkpoint (SAC) ensures that all kinetochores are correctly attached before its ...
Anna Stockum +2 more
doaj +1 more source