Advanced sleep spindle identification with neural networks [PDF]
Scientific Reports 12, 7686 (2022), 2022 Sleep spindles are neurophysiological phenomena that appear to be linked to memory formation and other functions of the central nervous system, and that can be observed in electroencephalographic recordings (EEG) during sleep. Manually identified spindle annotations in EEG recordings suffer from substantial intra- and inter-rater variability, even if ...
arxiv +1 more source
Cell Division, 2021 Background Ral family is a member of Ras-like GTPase superfamily, which includes RalA and RalB. RalA/B play important roles in many cell biological functions, including cytoskeleton dynamics, cell division, membrane transport, gene expression and signal ...
Ming-Hong Sun +7 more
doaj +1 more source
Mechanisms of spindle bipolarity establishment in acentrosomal human cells
Molecular & Cellular Oncology, 2020 Centrosomes are not absolutely essential for cell division; acentrosomal bipolar spindles can be established in oocytes and centrosome-eliminated somatic cells.
Kaho Hashimoto +2 more
doaj +1 more source
The association between muscle architecture and muscle spindle abundance
Scientific Reports, 2023 Across the human body, skeletal muscles have a broad range of biomechanical roles that employ complex proprioceptive control strategies to successfully execute a desired movement.
Roger W. P. Kissane +3 more
doaj +1 more source
Aflatoxin B1 exposure disrupts organelle distribution in mouse oocytes [PDF]
PeerJ, 2022 Aflatoxin B1 (AFB1) is a secondary metabolite produced by the fungus Aspergillus, which is ubiquitous in moldy grain products. Aflatoxin B1 has been reported to possess hepatotoxicity, renal toxicity, and reproductive toxicity.
Yan-Zhe Zhang +5 more
doaj +2 more sources
PLoS ONE, 2012 The mitotic spindle is an essential molecular machine involved in cell division, whose composition has been studied extensively by detailed cellular biology, high-throughput proteomics, and RNA interference experiments.
Ana M Rojas +20 more
doaj +1 more source
The spindle matrix protein, Chromator, is a novel tubulin binding protein that can interact with both microtubules and free tubulin. [PDF]
PLoS ONE, 2014 The chromodomain protein, Chromator, is localized to chromosomes during interphase; however, during cell division together with other nuclear proteins Chromator redistributes to form a macro molecular spindle matrix complex that embeds the microtubule ...
Changfu Yao +8 more
doaj +1 more source
Morphogenetic forces planar polarize LGN/Pins in the embryonic head during Drosophila gastrulation
eLife, 2022 Spindle orientation is often achieved by a complex of Partner of Inscuteable (Pins)/LGN, Mushroom Body Defect (Mud)/Nuclear Mitotic Apparatus (NuMa), Gαi, and Dynein, which interacts with astral microtubules to rotate the spindle.
Jaclyn Camuglia +2 more
doaj +1 more source
A permeabilized cell model for studying cell division: a comparison of anaphase chromosome movement and cleavage furrow constriction in lysed PtK1 cells. [PDF]
, 1981 After lysis in a Brij 58-polyethylene glycol medium, PtK1 cells are permeable to small molecules, such as erythrosin B, and to proteins, such as rhodamine-labeled FAB, myosin subfragment-1, and tubulin.
CANDE, W. Zacheus +2 more
core +2 more sources
CKAP2 ensures chromosomal stability by maintaining the integrity of microtubule nucleation sites. [PDF]
PLoS ONE, 2013 Integrity of the microtubule spindle apparatus and intact cell division checkpoints are essential to ensure the fidelity of distributing chromosomes into daughter cells.
Chanelle M Case +6 more
doaj +1 more source