The association between muscle architecture and muscle spindle abundance
Scientific Reports, 2023 Across the human body, skeletal muscles have a broad range of biomechanical roles that employ complex proprioceptive control strategies to successfully execute a desired movement.
Roger W. P. Kissane +3 more
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PLoS ONE, 2012 The mitotic spindle is an essential molecular machine involved in cell division, whose composition has been studied extensively by detailed cellular biology, high-throughput proteomics, and RNA interference experiments.
Ana M Rojas +20 more
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Generation and Characterization of a Tissue-Specific Centrosome Indicator Mouse Line. [PDF]
, 2016 Centrosomes are major microtubule organizing centers (MTOCs) that play an important role in chromosome segregation during cell division. Centrosomes provide a stable anchor for microtubules, constituting the centers of the spindle poles in mitotic cells,
Chen, Ju +2 more
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Effects of pentoxifylline on mouse oocytes maturation and qualityin vitro [PDF]
Iranian Journal of Basic Medical SciencesObjective(s): To investigate the impact of Pentoxifylline (PTX) on the in vitro maturation (IVM) of mouse oocytes and its effect on oocyte quality.Materials and Methods: This experimental study involved culturing mouse oocytes in an IVM medium with ...
Wu Junjiao, Wu Jianbo, Yanyan Xu
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The spindle matrix protein, Chromator, is a novel tubulin binding protein that can interact with both microtubules and free tubulin. [PDF]
PLoS ONE, 2014 The chromodomain protein, Chromator, is localized to chromosomes during interphase; however, during cell division together with other nuclear proteins Chromator redistributes to form a macro molecular spindle matrix complex that embeds the microtubule ...
Changfu Yao +8 more
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Aflatoxin B1 exposure disrupts organelle distribution in mouse oocytes [PDF]
PeerJ, 2022 Aflatoxin B1 (AFB1) is a secondary metabolite produced by the fungus Aspergillus, which is ubiquitous in moldy grain products. Aflatoxin B1 has been reported to possess hepatotoxicity, renal toxicity, and reproductive toxicity.
Yan-Zhe Zhang +5 more
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Morphogenetic forces planar polarize LGN/Pins in the embryonic head during Drosophila gastrulation
eLife, 2022 Spindle orientation is often achieved by a complex of Partner of Inscuteable (Pins)/LGN, Mushroom Body Defect (Mud)/Nuclear Mitotic Apparatus (NuMa), Gαi, and Dynein, which interacts with astral microtubules to rotate the spindle.
Jaclyn Camuglia +2 more
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A permeabilized cell model for studying cell division: a comparison of anaphase chromosome movement and cleavage furrow constriction in lysed PtK1 cells. [PDF]
, 1981 After lysis in a Brij 58-polyethylene glycol medium, PtK1 cells are permeable to small molecules, such as erythrosin B, and to proteins, such as rhodamine-labeled FAB, myosin subfragment-1, and tubulin.
CANDE, W. Zacheus +2 more
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CKAP2 ensures chromosomal stability by maintaining the integrity of microtubule nucleation sites. [PDF]
PLoS ONE, 2013 Integrity of the microtubule spindle apparatus and intact cell division checkpoints are essential to ensure the fidelity of distributing chromosomes into daughter cells.
Chanelle M Case +6 more
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Chromosome Centromeres: Structural and Analytical Investigations with High Resolution Scanning Electron Microscopy in Combination with Focused Ion Beam Milling [PDF]
, 2009 Whole mount mitotic metaphase chromosomes of different plants and animals were investigated with high resolution field emission scanning electron microscopy (FESEM) to study the ultrastructural organization of centromeres, including metacentric ...
Schroeder-Reiter, E., Wanner, Gerhard
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