Results 31 to 40 of about 995,356 (273)

The post-translational modification of NuMA in cancer cells is a new target for cancer eradication [PDF]

Cell Death and Disease
Recent findings identify a cell-death mechanism in human cancer cells, based on the inhibition of the post-translational modification of NuMA (nuclear mitotic apparatus protein) in cancer cells, which interferes with its protein-binding capacity. NuMA is
Malka Cohen-Armon
doaj   +2 more sources

Silencing of spindle apparatus coiled-coil protein 1 suppressed the progression of hepatocellular carcinoma through farnesyltransferase-beta and increased drug sensitivity. [PDF]

Heliyon
Zhai Y, Wu F, Xu X, Zhao P, Xin L, Li M, Zong Y, Yang Z, Li Z, Wang L, Chen B.   +10 more
europepmc   +3 more sources

The mushroom body defect Gene Product Is an Essential Component of the Meiosis II Spindle Apparatus in Drosophila Oocytes [PDF]

Genetics, 2006
James X Yu, Zhonghui Guan, Howard A. Nash   +2 more
openalex   +2 more sources

Rare Antinuclear Antibody Patterns: Relevance in Routine Laboratory Reporting [PDF]

Journal of Clinical and Diagnostic Research, 2023
Introduction: Uncommon patterns on Human Epithelial 2 (Hep 2) substrate during Antinuclear Antibody (ANA) screening by Indirect Immunofluorescence (IIF) microscopy are not routinely reported by many laboratories since their clinical relevance is not well
Vidya Bhakta
doaj   +1 more source

Evidence for spindle apparatus in somatic nuclei

Fungal Genetics Reports, 1971
W. B. Van Winkle
openalex   +4 more sources

Genetic Disorders Affecting Tubulin Cytoskeleton [PDF]

Journal of Biomedical & Clinical Research, 2015
The tubulin cytoskeleton is vital for maintenance and dynamics of eukaryotic cells and molecular defects in its components can lead to serious conditions.
Maya Markova, Irina Chakarova, Ralitsa Zhivkova, Venera Nikolova, Valentina Hadzhinesheva, Stefka Delimitreva   +5 more
doaj   +3 more sources

A Balance between Nuclear and Cytoplasmic Volumes Controls Spindle Length. [PDF]

PLoS ONE, 2016
Proper assembly of the spindle apparatus is crucially important for faithful chromosome segregation during anaphase. Thanks to the effort over the last decades, we have very detailed information about many events leading to spindle assembly and ...
Lucia Novakova, Kristina Kovacovicova, Thanh Quang Dang-Nguyen, Martin Sodek, Michal Skultety, Martin Anger   +5 more
doaj   +1 more source

TheDrosophilaγ-Tubulin Small Complex Subunit Dgrip84 Is Required for Structural and Functional Integrity of the Spindle Apparatus

Molecular Biology of the Cell, 2005
Nathalie Colombié, Christel Vérollet, Paula Sampaio, André Moisand, Cláudio E. Sunkel, Henri-Marc Bourbon, Michel Wright, Brigitte Raynaud‐Messina   +7 more
openalex   +2 more sources

USP11 deubiquitinates RAE1 and plays a key role in bipolar spindle formation. [PDF]

PLoS ONE, 2018
Correct segregation of the mitotic chromosomes into daughter cells is a highly regulated process critical to safeguard genome stability. During M phase the spindle assembly checkpoint (SAC) ensures that all kinetochores are correctly attached before its ...
Anna Stockum, Ambrosius P Snijders, Goedele N Maertens   +2 more
doaj   +1 more source

Dynamic Localization of the Human Papillomavirus Type 11 Origin Binding Protein E2 through Mitosis While in Association with the Spindle Apparatus

Journal of Virology, 2006
Luan D. Dao, Aaron A. Duffy, Brian A. Van Tine, Shwu‐Yuan Wu, Cheng‐Ming Chiang, Thomas R. Broker, Louise T. Chow   +6 more
openalex   +2 more sources