Disjunction of conjoined twins: Cdk1, Cdh1 and separation of centrosomes
Accurate transmission of chromosomes from parent to progeny cell requires assembly of a bipolar spindle. Centrosomes (spindle pole body in yeast) are critical for the biogenesis of this complex mitotic apparatus since they confer bipolarity on the ...
Surana Uttam, Crasta Karen
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Study of how the synthesis conditions of circular optical scales fabricated using a CLWS-300 laser image generator affect their angular errors [PDF]
This paper discusses the results of a study of how the synthesis conditions of circular optical scales fabricated using a laser image generator affect their angular errors.
Andronov, M. P.+2 more
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A regulatory effect of INMAP on centromere proteins: antisense INMAP induces CENP-B variation and centromeric halo. [PDF]
CENP-B is a highly conserved protein that facilitates the assembly of specific centromere structures both in interphase nuclei and on mitotic chromosomes. INMAP is a conserved protein that localizes at nucleus in interphase cells and at mitotic apparatus
Tan Tan+4 more
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To understand general features in evolution of kinetochore organization, investigating a wide range of mitotic mechanisms in various non-model eukaryotes is necessary.
Pavla Tůmová+2 more
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A comparison of the distribution of actin and tubulin in the mammalian mitotic spindle as seen by indirect immunofluorescence [PDF]
Rabbit antibodies against actin and tubulin were used in an indirect immunofluorescence study of the structure of the mitotic spindle of PtK1 cells after lysis under conditions that preserve anaphase chromosome movement. During early prophase there is no
Cande, W. Zacheus+2 more
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Dominant-Negative Effects of Adult-Onset Huntingtin Mutations Alter the Division of Human Embryonic Stem Cells-Derived Neural Cells. [PDF]
Mutations of the huntingtin protein (HTT) gene underlie both adult-onset and juvenile forms of Huntington's disease (HD). HTT modulates mitotic spindle orientation and cell fate in mouse cortical progenitors from the ventricular zone.
Carla Lopes+7 more
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Two major autoantigen—Antibody systems of the mitotic spindle apparatus [PDF]
AbstractObjective. To characterize human autoantigen‐antibody systems related to the mitotic poles and spindles.Methods. Thirty‐seven human sera with autoantibodies staining mitotic poles and spindles in indirect immunofluorescence (IIF) studies were further characterized by immunofluorescence on mitotic cells and by immunoblotting and ...
Luis Eduardo Coelho Andrade+3 more
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Fertilized Zhikong scallop (Chlamys farreri) eggs were treated with cytochalasin B (CB 0.5 mg/L) at 14–15 min postfertilization to inhibit first polar body formation.
Yongren Li+3 more
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Evolutionary cell biology of chromosome segregation: insights from trypanosomes [PDF]
Faithful transmission of genetic material is essential for the survival of all organisms. Eukaryotic chromosome segregation is driven by the kinetochore that assembles onto centromeric DNA to capture spindle microtubules and govern the movement of ...
Bungo Akiyoshi, Keith Gull
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Microtubule and Actin Cytoskeletal Dynamics in Male Meiotic Cells of Drosophila melanogaster
Drosophila dividing spermatocytes offer a highly suitable cell system in which to investigate the coordinated reorganization of microtubule and actin cytoskeleton systems during cell division of animal cells.
Anna Frappaolo+2 more
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