Results 41 to 50 of about 1,379,565 (255)
Phospho‐regulation of mitotic spindle assembly [PDF]
, 2020 The assembly of the bipolar mitotic spindle requires the careful orchestration of a myriad of enzyme activities like protein posttranslational modifications.
Torres, Jorge Z +5 more
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Biology Open, 2013 Summary In animal cells the centrosome is commonly viewed as the main cellular structure driving microtubule (MT) assembly into the mitotic spindle apparatus.
Nicolas Lecland +10 more
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Dynamics of myosin, microtubules, and Kinesin-6 at the cortex during cytokinesis in Drosophila S2 cells [PDF]
, 2009 © The Authors, 2009 . This article is distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. The definitive version was published in Journal of Cell Biology 186 (2009): 727-738, doi:10.1083/jcb ...
Vale, Ronald D. +5 more
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New mitotic regulators released from chromatin
Frontiers in Oncology, 2013 Faithful action of the mitotic spindle segregates duplicated chromosomes into daughter cells. Perturbations of this process result in chromosome mis-segregation, leading to chromosomal instability and cancer development.
Hideki eYokoyama, Oliver eGruss
doaj +1 more source
Bub1 kinase in the regulation of mitosis
Animal Cells and Systems, 2021 Accurate chromosome segregation is required for cell survival and organismal development. During mitosis, the spindle assembly checkpoint acts as a safeguard to maintain the high fidelity of mitotic chromosome segregation by monitoring the attachment of ...
Taekyung Kim, Anton Gartner
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On the regulation of chromosome segregation in human cells : implications of Bub1 Kinase inhibition during cell division [PDF]
, 2015 The maintenance of correct chromosome number (euploidy) during cell division is essential for health. Loss of euploidy is observed in most cancers and is linked to tumorigenesis.
Baron, Anna
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Life Science AllianceTubulin dimers concentrate within an ER spindle envelope because cytoplasmic organelles outside the envelope occupy significant volume. In many animal species, the oocyte meiotic spindle, which is required for chromosome segregation, forms without ...
Ting Gong +6 more
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PLoS Genetics, 2020 The requirements for oocyte meiotic cytokinesis during polar body extrusion are not well understood. In particular, the relationship between the oocyte meiotic spindle and polar body contractile ring dynamics remains largely unknown.
Aleesa J Schlientz, Bruce Bowerman
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Checkpoint proteins come under scrutiny [PDF]
, 2013 Details are emerging of the interactions between the kinetochore and various spindle checkpoint proteins that ensure that sister chromatids are equally divided between daughter cells during cell ...
Jonathan BA Millar +3 more
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Initial Characterization of two novel spindle proteins, CHICA and HURP [PDF]
, 2008 During mitotic spindle assembly, the sister chromatids have to be captured by kinetochore (K) -fibers (bundles of kinetochore microtubules; KMTs) to ensure stable attachment of the chromosomes.
Nagel, Susanna
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