Results 61 to 70 of about 51,274 (213)

Deubiquitinase USP38 Stabilizes PLK1 Expression to Boost DNA Damage Repair in Ovarian Cancer

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ovarian cancer (OC) is one of the most prevalent and severe gynecological malignant tumors. DNA damage repair (DDR) is essential in maintaining genome stability. This study aims to investigate the effects and mechanisms of USP38 and PLK1 on DNA damage repair and malignant behavior in OC cells.
Yuan Ma, Ying Li, Kai‐Li Li
wiley   +1 more source

Research Testing of Structural Assembly to Wind Turbine Blade Direct Reuse

Macromolecular Symposia, EarlyView.
ABSTRACT The global production of wind energy has increased significantly, representing a basic component in the energy industry, and the blade materials need an intelligent recycling with sustainable transformation. The blades manufactured using fiberglass are found in many applications, considering their superior properties.
Claudiu Bisu, Dorel Anania, Andra Pena, Dragos Apostol, Cristina Mohora, Constantin Gheorghe Opran   +5 more
wiley   +1 more source

Apple scar skin viroid causes dapple and scar skin apple diseases by disrupting phenylpropanoid‐mediated metabolic pathways

New Plant Protection, EarlyView.
Dapple apple and scar skin apple diseases are closely associated with suppression of anthocyanin biosynthesis and enhancement of suberin biosynthesis. Apple scar skin viroid (ASSVd) infection represses anthocyanin biosynthesis in apple callus. Abstract Apple scar skin viroid (ASSVd) causes dapple and scar skin apple diseases, posing serious threats to ...
Lingzhu He, Huiyuan Xu, Tao Zhou, Naoi Takashi, Sano Teruo, Guojun Hu, Jipeng Xie, Xiuling Yang, Shifang Li, Zhixiang Zhang   +9 more
wiley   +1 more source

Genetic analysis of primary lung interdigitating dendritic cell sarcomas

The Journal of Pathology, EarlyView.
Abstract Interdigitating dendritic cell sarcomas (IDCSs) are rare tumors that commonly arise in the hematopoietic system and rarely outside. The genetic drivers of IDCS carcinogenesis are unknown; therefore, therapeutic options are limited. We investigated somatic gene mutations and copy‐number alterations (CNAs) in nine IDCSs arising in the lung by ...
Mikhail S Ermakov, Juliana Faria Filipe, Sylvia Eidenhammer, German Ott, Iris Halbwedl, Karl Kashofer, Helmut Popper   +6 more
wiley   +1 more source

Transcriptomic comparative study between canalicular adenoma and HMGA2::WIF1 canalicular‐like pleomorphic adenoma

The Journal of Pathology, EarlyView.
Abstract Canalicular adenoma (CA) is a benign salivary gland tumor predominantly affecting the upper lip and is characterized by monomorphic epithelial cells arranged in branching cords within a loose and vascularized stroma. Unlike pleomorphic adenoma (PA), CA lacks a chondroid matrix and exhibits specific histological features, such as high cuboidal ...
Ziyad Alsugair, Anne Champagnac, Maxime Fieux, Pierre Philouze, Philippe Ceruse, Brice Thamphya, Daniel Pissaloux, Franck Tirode, Nazim Benzerdjeb   +8 more
wiley   +1 more source

Mechanism of spindle assembly in Schizosaccharomyces pombe - The role of microtubule pivoting in spindle assembly

, 2016
At the onset of cell division microtubules growing from spindle pole bodies (SPB) interact with each other to form the mitotic spindle enabling proper chromosome positioning and segregation. However, the exact mechanism of microtubule dynamics and microtubule associated proteins (MAPs) underlying spindle assembly is still not well understood.
openaire   +2 more sources

Proteomic Characterization of AS1411 Reveals ATP6AP1 as a Mediator of Triple‐Negative Breast Cancer Progression

PROTEOMICS, EarlyView.
ABSTRACT Triple‐negative breast cancer (TNBC) is an aggressive subtype of breast cancer characterized by high metastatic potential, poor prognosis, and limited effective therapeutic options. In this study, we investigated the molecular mechanisms underlying the anticancer effects of the nucleolin (NCL)‐targeting DNA aptamer AS1411 using label‐free ...
Ha‐Song Bae, Yun‐Jeong Seo, Eun‐Bi Kim, Hyoung‐Min Park, I‐Hsuan Liu, J. Eugene Lee, Jae‐Young Kim   +6 more
wiley   +1 more source

First genome sequence of a European Alternaria brassicae isolate and genes involved in early development of alternaria leaf spot on Brassica juncea

Pest Management Science, EarlyView.
This article reports the first genome sequence of a UK Alternaria brassicae isolate. Dual RNA‐sequencing profiling of A. brassicae‐infected Brassica juncea leaves identified differentially expressed genes involved in pathogenicity and host response pathways in moderately resistant Sej‐2 (2) and moderately susceptible Pusa Jaikisan cultivars.
Kevin M. King, Graham McLaughlin, Chinthani S. Karandeni Dewage, Zedi Gao, David J. Hughes, Jonathan S. West, Henrik U. Stotz   +6 more
wiley   +1 more source

Actuation Strategies for Underwater Jet‐Propelled Soft Robots

Journal of Field Robotics, EarlyView.
ABSTRACT This review article examines jet‐propulsion mechanisms in underwater soft robotic systems, focusing exclusively on physically fabricated and experimentally validated robots. Covering research published from 2013 to 2025, this study classifies and evaluates jet‐propulsion robots based on their actuation mechanisms.
Angel Kitone, Mohammed Anteet, Pawandeep S. Matharu, Yara Almubarak   +3 more
wiley   +1 more source

Micronuclei and Other Nuclear Abnormalities in Patella Limpet as Biomarkers of Cytogenotoxicity in Recreational Port Waters

Environmental Toxicology, EarlyView.
ABSTRACT Over the past decades, the growth in human population and economic activities has led to an increase in maritime traffic. This rise puts additional pressure on marine environments, vessel fuel spills being considered to have a major impact on the ecosystem.
Carlos Valiente‐Diaz, Eva Garcia‐Vazquez, Verónica Soto‐López   +2 more
wiley   +1 more source