The spindle assembly checkpoint (SAC) and spindle position checkpoint (SPOC) are essential surveillance systems that ensure accurate chromosome segregation and proper spindle orientation during mitosis.
Bashar Ibrahim
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Editorial: Chromosome bi-orientation, tension and the spindle-assembly checkpoint. [PDF]
Schuyler SC.
europepmc +1 more source
Spindle assembly checkpoint insensitivity allows meiosis-II despite chromosomal defects in aged eggs. [PDF]
Mihajlović AI +3 more
europepmc +1 more source
Deubiquitinase USP8 regulates the spindle assembly checkpoint in oocytes. [PDF]
Zhou 周长银 C +7 more
europepmc +1 more source
Functional framework of the kinetochore and spindle assembly checkpoint in Arabidopsis. [PDF]
Pettkó-Szandtner A, Magyar Z, Komaki S.
europepmc +1 more source
MRE11 orchestrates porcine oocyte meiotic progression by modulating the spindle assembly checkpoint. [PDF]
Zhang D +8 more
europepmc +1 more source
Evaluation of the Spindle Assembly Checkpoint Integrity in Mouse Oocytes. [PDF]
Aboelenain M, Schindler K, Blengini CS.
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Mechanisms of Spindle Assembly Checkpoint Silencing
The spindle assembly checkpoint (SAC) is a genome surveillance mechanism that protects against aneuploidization. Over the years, through a combination ofcell biology, evolutionary analysis and top-of-the-nudge biochemical techniques, significant progress has been achieved in unravelling and understanding the molecular mechanisms supporting the SAC ...
openaire +2 more sources
Role of spindle assembly checkpoint proteins in gametogenesis and embryogenesis. [PDF]
Pun R, North BJ.
europepmc +1 more source
Adaptation to spindle assembly checkpoint inhibition through the selection of specific aneuploidies. [PDF]
Adell MAY +7 more
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