Determinants for robustness in spindle assembly checkpoint signaling
In eukaryotes, the spindle assembly checkpoint (SAC) is crucial to ensure fidelity of chromosome segregation in mitosis. Malfunction of this checkpoint leads to chromosome segregation errors and has been implicated in tumorigenesis.
Knop, N. +9 more
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NEK2 is essential for spindle assembly checkpoint regulation and cytoskeleton organization in porcine oocyte meiotic maturation. [PDF]
Jeon SB +10 more
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Deubiquitinase USP8 regulates the spindle assembly checkpoint in oocytes. [PDF]
Zhou 周长银 C +7 more
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Retraction: A new Mad2-interacting domain of Cdc20 is critical for the function of Mad2-Cdc20 complex in the spindle assembly checkpoint. [PDF]
Roychoudhury S, Mondal G, Baral RN.
europepmc +1 more source
KIF18A inhibitor prevents chromosomally unstable osteosarcoma growth by activating spindle assembly checkpoint. [PDF]
Yan Q +8 more
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Editorial: Chromosome bi-orientation, tension and the spindle-assembly checkpoint. [PDF]
Schuyler SC.
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Mitotic error correction and the spindle assembly checkpoint: a tension-filled relationship. [PDF]
Pleuger R, Westermann S.
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hSpindly dynamics modulate spindle assembly checkpoint signaling, promoting resistance to mitotic inhibitors. [PDF]
Mora-Santos M +5 more
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Correction: PIGN spatiotemporally regulates the spindle assembly checkpoint proteins in leukemia transformation and progression. [PDF]
Teye EK +9 more
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Spindle assembly checkpoint insensitivity allows meiosis-II despite chromosomal defects in aged eggs. [PDF]
Mihajlović AI +3 more
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