Results 101 to 110 of about 30,416 (203)
Reporting a Homozygous Case of Neurodevelopmental Disorder Associated With a Novel PRPF8 Variant
Molecular Genetics & Genomic MedicineBackground While recently identified heterozygous PRPF8 variants have been linked to various human diseases, their role in neurodevelopmental disorders (NDDs) remains ambiguous.
Mohammad Reza Mirinezhad +8 more
doaj +1 more source
Plant, Cell &Environment, Volume 49, Issue 8, Page 6169-6187, August 2026.ABSTRACT Improving photosynthesis is proposed as a means of enhancing crop productivity. To assess whether simultaneous increases in light use‐efficiency and carbon assimilation are additive, we investigated the impact of elevated CO2 on the performance of a transgenic soybean line engineered for faster relaxation of photoprotection by overexpression ...
Dilkaran Singh +6 more
wiley +1 more source
Plant Biology, Volume 28, Issue 5, Page 1686-1697, August 2026.We generated a compound by chemical modification that can efficiently rescue growth without decreasing the immune response of the chs3‐2D autoimmune mutants, thus chemically uncoupling its growth–defence trade‐off. Abstract Plant development in many species including Arabidopsis relies on the accurate balance between growth and defence.
M. Keijzer +5 more
wiley +1 more source
International Journal of Cancer, Volume 159, Issue 2, Page 302-319, 15 July 2026.Abstract Tumor‐educated platelets (TEPs) are emerging as a compelling frontier in liquid biopsy, functioning as dynamic, systemic sensors that sequester and process tumor‐derived biomolecules. This interaction imprints an integrated molecular signature of malignancy—spanning the transcriptome, proteome, lipidome, and crucially, the captured genome ...
Whi‐An Kwon +5 more
wiley +1 more source
International Journal of Cancer, Volume 159, Issue 2, Page 501-515, 15 July 2026.What's new? Esophageal adenocarcinoma (EAC) is an aggressive cancer with poor survival and variable response to perioperative chemotherapy. Although histopathological features correlate with outcomes, the relationship specifically between adherens junction (AJ) protein expression and treatment response in EAC remains uncertain.
Bastian Grothey +8 more
wiley +1 more source
FMRP‐Mediated Proteasome Regulation: A Novel Mechanism in ALS Pathology
The FASEB Journal, Volume 40, Issue 13, 15 July 2026.Schematic model of TDP‐43/TNKS‐mediated proteasome regulation in WT, FMRP‐depleted, and TDP‐43A315T‐Tg ALS neurons. In WT neurons, cytoplasmic TDP‐43 partially sequesters TNKS, maintaining balanced PI31 ribosylation and proteasome activity. FMRP depletion promotes nuclear translocation of TDP‐43, enhances TNKS/PI31 interaction, and increases axonal ...
Pritha Majumder +5 more
wiley +1 more source
Probing the genomic and proteomic basis of encystment in Oxytricha granulifera
mSystemsProtozoan encystment constitutes a pivotal survival strategy against environmental stressors; however, the molecular architecture governing this transition remains enigmatic, owing to limited genomic resources and a scarcity of integrated multi-omics ...
Miaomiao Wang +7 more
doaj +1 more source
Synthetic Ligands of Myeloid C‐Type Lectin Receptors
ChemBioChem, Volume 27, Issue 13, 14 July 2026.Binding of ligands to C‐type lectin receptors (CLRs) on myeloid cells can lead to an array of cellular responses. Exploitation of these receptors for therapeutic purposes requires high‐affinity ligands. This review surveys the diversity of synthetic ligands of myeloid CLRs in the context of binding, signaling, and downstream effects, as well as ...
James Suri, Bernd Lepenies
wiley +1 more source