Results 151 to 160 of about 51,251 (260)

Mining Potential Therapeutic Targets for T Cell Exhaustion in Osteoarthritis by Integrating Mendelian Randomization and Single‐Cell Sequencing

The FASEB Journal, Volume 40, Issue 2, 31 January 2026.
This study conducted an integrated analysis using multi‐source data, with specific data sources including the GEO database (encompassing datasets GSE55235, GSE55457, and GSE152805), literature‐mined gene sets, and the IEU OpenGWAS database (dataset ebi‐a‐GCST005814).
Jiahong Li, Yi Ye, Yan Zhang, Wei Fang, Fei Lan, Qian Yang, Lun Wan, Jiang Hu, Chengwei Xiao, Kun Zhang   +9 more
wiley   +1 more source

Saccharomyces cerevisiae NineTeen Complex (NTC)-associated Factor Bud31/Ycr063w Assembles on Precatalytic Spliceosomes and Improves First and Second Step Pre-mRNA Splicing Efficiency [PDF]

, 2012
Debjani Saha, Piyush Khandelia, Raymond T. O’Keefe, Usha Vijayraghavan   +3 more
openalex   +1 more source

Impact of Bisphenol-A on the Spliceosome and Meiosis of Sperm in the Testis of Adolescent Mice [PDF]

, 2021
Yongjie Wang, Yanyan Wu, Shilei Zhang
openalex   +1 more source

Spliceosomal Factor SmF Modulates Temperature‐Mediated Flower and Leaf Size Plasticity in Arabidopsis thaliana

Plant, Cell &Environment, EarlyView.
Gregory M. Andreou‐Huotari, Mikael Brosché, Jan Hoffmann, Zoran Nikoloski, Roosa A. E. Laitinen   +4 more
wiley   +1 more source

Gezielte Modulation des spliceosomalen Proteins USP39 durch allosterische Liganden und PROTAC‐induzierte Degradation

Angewandte Chemie, Volume 138, Issue 5, 28 January 2026.
Proteolysis‐targeting Chimeras (PROTACs) ermöglichen die gezielte Degradation bislang als „undruggable“ geltende Proteine über das zelluläre Ubiquitin–Proteasom‐System. In dieser Studie identifizieren Schäfer et al. thiazolbasierte niedermolekulare Liganden, die allosterisch an die Zinkfinger‐Domäne der Ubiquitin‐spezifischen Protease 39 (USP39) binden
Daniel Schäfer, Cristian Prieto‐Garcia, Jianhui Wang, Marcel Heinz, Vigor Matkovic, Pavel Kielkowski, Sebastian Hasselbeck, Varun Jayeshkumar Shah, Stefan Knapp, Gerhard Hummer, Ivan Dikic, Xinlai Cheng   +11 more
wiley   +1 more source

Reporting a Homozygous Case of Neurodevelopmental Disorder Associated With a Novel PRPF8 Variant

Molecular Genetics & Genomic Medicine
Background While recently identified heterozygous PRPF8 variants have been linked to various human diseases, their role in neurodevelopmental disorders (NDDs) remains ambiguous.
Mohammad Reza Mirinezhad, Farzaneh Mirzaei, Arash Salmaninejad, Reza Jafarzadeh Esfehani, Mohammad Reza Seyedtaghia, Sheyda Farahmand, Mehran Beiraghi Toosi, Somayyeh Hashemian, M. E. Suzzane Lewis   +8 more
doaj   +1 more source

Partial purification of the yeast U2 snRNP reveals a novel yeast pre-mRNA splicing factor required for pre-spliceosome assembly [PDF]

, 1999
Friederike Caspary
openalex   +1 more source

Erratum to spliceosome-associated protein 130: a novel biomarker for idiopathic pulmonary fibrosis

, 2021
Editorial Office
openalex   +1 more source

Versatile and Selective Biomolecule Pulldown with Combinatorial DNA‐Crosslinked Polymers

Angewandte Chemie International Edition, Volume 65, Issue 5, 28 January 2026.
We present a programmable smart polymer system for universal, sequence‐selective bioseparation under native conditions. Polymer phase separation is achieved through combinatorial DNA crosslinking, enabling the capture of DNA, RNA, or proteins in a homogeneous solution with high pulldown efficiency and near‐zero background binding.
Sarah K. Speed, Krishna Gupta, Yu‐Hsuan Peng, Elisha Krieg   +3 more
wiley   +1 more source

Spliceosome [PDF]

Science-Business eXchange, 2009
openaire   +2 more sources