Results 121 to 130 of about 13,616 (222)

Spliceosomal snRNAs [PDF]

Cell, 2002
Villa, Tommaso, Pleiss, Jeffrey A, Guthrie, Christine   +2 more
openaire   +1 more source

Structural investigation of human U6 snRNA recognition by spliceosomal recycling factor SART3 RNA recognition motifs

The FEBS Journal, Volume 293, Issue 5, Page 1323-1340, March 2026.
Human SART3 has two RRM domains to engage with U6 snRNA for spliceosome recycling. This study reports solution structures of SART3 RRM domains and investigates the interaction between RRM and U6 snRNA. SART3 binds to the asymmetric bulge of U6 snRNA as a dimer via conserved positively charged surfaces.
Iktae Kim, Kyeong‐Mi Bang, So Young An, Changkon Park, Ji‐Yeon Shin, Youngim Kim, Hyun Kyu Song, Jeong‐Yong Suh, Nak‐Kyoon Kim   +8 more
wiley   +1 more source

Proteomic insights into the invasiveness and tumor progression of non‐functioning pituitary adenomas: A scoping review

Journal of Neuroendocrinology, Volume 38, Issue 3, March 2026.
Abstract Nonfunctioning pituitary adenomas (NFPAs) are common intracranial tumors that, despite being histologically benign, can exhibit invasive growth, as well as postoperative tumor progression. Surgical resection is the primary treatment of choice; however, residual tumor tissue is frequently observed, with between 30% and 50% of these cases ...
Thomas Skoglund, Linus Köster, Annika Thorsell, Oskar Ragnarsson, Gudmundur Johannsson, Tobias Hallén   +5 more
wiley   +1 more source

Phosphate Resupply Differentially Impacts the Shoot and Root Proteomes of Arabidopsis thaliana Seedlings

Plant, Cell &Environment, Volume 49, Issue 3, Page 1598-1616, March 2026.
ABSTRACT Phosphate (Pi) is an essential macronutrient for plant development that is often limited in soil. Plants have evolved dynamic biochemical, physiological and morphological adaptations to cope with Pi deficiency, known as the Pi starvation response (PSR).
Milena A. Smith, Lauren E. Grubb, Kirsten H. Benidickson, Devang Mehta, William C. Plaxton, R. Glen Uhrig   +5 more
wiley   +1 more source

Forks in the tracks: Group II introns, spliceosomes, telomeres and beyond

RNA Biology, 2016
R. Agrawal, Hongwei Wang, M. Belfort
semanticscholar   +1 more source

The RNA helicase Aquarius exhibits structural adaptations mediating its recruitment to spliceosomes

Nature Structural &Molecular Biology, 2015
Inessa De, Sergey Bessonov, Romina V. Hofele, K. D. Santos, C. Will, H. Urlaub, R. Lührmann, V. Pena   +7 more
semanticscholar   +1 more source

LncRNA evf‐2 Exacerbates Podocyte Injury in Diabetic Nephropathy by Inducing Cell Cycle Re‐entry and Inflammation Through Distinct Mechanisms Triggered by hnRNPU

Advanced Science
Albuminuria is a hallmark of diabetic nephropathy (DN). Podocyte injury significantly contributes to proteinuria in DN. Our study found that lncRNA EVF‐2 is upregulated in podocytes of DN patients, correlating with cell cycle re‐entry and inflammation ...
Chaojie Zhang, Hui Zhao, Yufan Yan, Yanfei Li, Min Lei, Yong Liu, Longhua Yang, Huijian Zhao, Sijie Zhou, Shaokang Pan, Zhangsuo Liu, Jia Guo   +11 more
doaj   +1 more source

New mechanistic insights into Prp22-mediated exon ligation and mRNA release. [PDF]

Nucleic Acids Res
Chung CS, Tseng CK, Chen HC, Cheng SC.
europepmc   +1 more source

Control of 3' splice site selection in S. cerevisiae by a highly conserved amino acid within the Prp8 α-finger domain. [PDF]

RNA
Liu Y, Paulson JC, Hoskins AA.
europepmc   +1 more source

Post-transcriptional spliceosomes are retained in nuclear speckles until splicing completion

Nature Communications, 2012
Cyrille Girard, C. Will, Jianhe Peng, E. Makarov, B. Kastner, I. Lemm, H. Urlaub, K. Hartmuth, R. Lührmann   +8 more
semanticscholar   +1 more source