Results 1 to 10 of about 42,005 (248)

Accumulation of squalene in a microalga Chlamydomonas reinhardtii by genetic modification of squalene synthase and squalene epoxidase genes. [PDF]

open access: yesPLoS ONE, 2015
Several microalgae accumulate high levels of squalene, and as such provide a potentially valuable source of this useful compound. However, the molecular mechanism of squalene biosynthesis in microalgae is still largely unknown.
Masataka Kajikawa   +5 more
doaj   +4 more sources

Production of squalene and fatty acids by Thraustochytrium sp. RT2316-16: effects of dissolved oxygen and the medium composition [PDF]

open access: yesBioresources and Bioprocessing
Thraustochytrium sp. RT2316-16 is a versatile marine microbe that produces useful compounds including docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), carotenoids and coenzyme Q10.
Paris Paredes   +5 more
doaj   +2 more sources

Biological and Pharmacological Activities of Squalene and Related Compounds: Potential Uses in Cosmetic Dermatology [PDF]

open access: yesMolecules, 2009
Squalene is a triterpene that is an intermediate in the cholesterol biosynthesis pathway. It was so named because of its occurrence in shark liver oil, which contains large quantities and is considered its richest source.
Jia-You Fang
exaly   +3 more sources

Extraction of Squalene From Tea Leaves (Camellia sinensis) and Its Variations With Leaf Maturity and Tea Cultivar

open access: yesFrontiers in Nutrition, 2022
Squalene is a precursor of steroids with diverse bioactivities. Tea was previously found to contain squalene, but its variation between tea cultivars remains unknown.
Yue Yue Sheng   +8 more
doaj   +1 more source

Squalene Supplementation as a Novel to Increase PUFA Content in Fish Tissues

open access: yesAnimals, 2023
Squalene is an antioxidant that plays an essential role in fat metabolism. The study aimed to assess the effect of squalene supplied in feed on the growth performance, health status, and fatty acid profiles of muscle and liver of Siberian sturgeon ...
Piotr Niewiadomski   +9 more
doaj   +1 more source

Metadata analysis of the squalene epoxidase gene in dermatophytes.

open access: yesInternational Journal of Endorsing Health Science Research, 2021
Background:Squalene epoxidase gene is an azole antifungal target enzyme in the ergosterol biosynthesis pathway in fungi—the inhibition of enzyme aggregate squalene, a type of ergosterol derivative depletion that leads to fungal growth inhibition.
Fatima Ismail, Iqra Ahmad, Eqaza Javed
doaj   +1 more source

Analysis of Antidiabetic Activity of Squalene via In Silico and In Vivo Assay

open access: yesMolecules, 2023
Squalene has been tested widely in pharmacological activity including anticancer, antiinflammatory, antioxidant, and antidiabetic properties. This study aims to examine antidiabetic activity of squalene in silico and in vivo models.
Tri Widyawati   +3 more
doaj   +1 more source

Adapting of a Method for Qualitative and Quantitative Determination of Squalene in Distillation Cuts of Sunflower Oil

open access: yesBIO Web of Conferences, 2021
Squalene is a naturally-occurring dihydro-triterpene hydrocarbon (C30H50) with six double bonds, which is an intermediate in the biosynthesis of phytosterol or cholesterol in plants or animals.
Dubrovskaya Irina   +3 more
doaj   +1 more source

Squalene synthase inhibitors [PDF]

open access: yesBritish Journal of Pharmacology, 2003
British Journal of Pharmacology (2003) 139, 881–882.
V C, Menys, P N, Durrington
openaire   +2 more sources

Squalene-Hopene Cyclases [PDF]

open access: yesApplied and Environmental Microbiology, 2011
ABSTRACTHopanoids and sterols are members of a large group of cyclic triterpenoic compounds that have important functions in many prokaryotic and eukaryotic organisms. They are biochemically synthesized from linear precursors (squalene, 2,3-oxidosqualene) in only one enzymatic step that is catalyzed by squalene-hopene cyclase (SHC) or oxidosqualene ...
Gabriele, Siedenburg, Dieter, Jendrossek
openaire   +2 more sources

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