Results 11 to 20 of about 42,005 (248)

Introduction of a green algal squalene synthase enhances squalene accumulation in a strain of Synechocystis sp. PCC 6803

open access: yesMetabolic Engineering Communications, 2020
Squalene is a triterpene which is produced as a precursor for a wide range of terpenoid compounds in many organisms. It has commercial use in food and cosmetics but could also be used as a feedstock for production of chemicals and fuels, if generated ...
Bagmi Pattanaik   +3 more
doaj   +1 more source

Diatoms synthesize sterols by inclusion of animal and fungal genes in the plant pathway [PDF]

open access: yes, 2020
Diatoms are ubiquitous microalgae that have developed remarkable metabolic plasticity and gene diversification. Here we report the first elucidation of the complete biosynthesis of sterols in the lineage.
, Angela   +7 more
core   +1 more source

Plasma squalene: lipoprotein distribution and kinetic analysis.

open access: yesJournal of Lipid Research, 1978
Plasma squalene concentration is increased in hypertriglyceridemia. In 24 normotriglyceridemic and 12 hypertriglyceridemic subjects, whole plasma squalene correlated strongly with plasma triglyceride (r = 0.973, P < 0.001) in the latter.
C D Saudek, B M Frier, G C Liu
doaj   +1 more source

Optimal NaCl Medium Enhances Squalene Accumulation in Thraustochytrium sp. ATCC 26185 and Influences the Expression Levels of Key Metabolic Genes

open access: yesFrontiers in Microbiology, 2022
Squalene, a natural lipid of the terpenoid family, is well-recognized for its roles in regulating cholesterol metabolism, preventing tumor development, and improving immunity.
Aiqing Zhang   +7 more
doaj   +1 more source

Improving squalene production by enhancing the NADPH/NADP+ ratio, modifying the isoprenoid-feeding module and blocking the menaquinone pathway in Escherichia coli

open access: yesBiotechnology for Biofuels, 2019
Background Squalene is currently used widely in the food, cosmetics, and medicine industries. It could also replace petroleum as a raw material for fuels. Microbial fermentation processes for squalene production have been emerging over recent years.
Wen Xu   +6 more
doaj   +1 more source

Production of squalene in Synechocystis sp. PCC 6803. [PDF]

open access: yesPLoS ONE, 2014
In recent years, there has been an increased interest in the research and development of sustainable alternatives to fossil fuels. Using photosynthetic microorganisms to produce such alternatives is advantageous, since they can achieve direct conversion ...
Elias Englund   +5 more
doaj   +1 more source

Squalene Biosynthesis in Engineered Escherichia Coli

open access: yesPharmaceutical Fronts, 2023
Squalene is a natural triterpenoid that is important in medicine, and daily-use chemical and nutraceutical industries. The demand for squalene remains high and constant.
Wei Zhang   +3 more
doaj   +1 more source

Hopanoids Play a Role in Membrane Integrity and pH Homeostasis in Rhodopseudomonas palustris TIE-1 [PDF]

open access: yes, 2009
Sedimentary hopanes are pentacyclic triterpenoids that serve as biomarker proxies for bacteria and certain bacterial metabolisms, such as oxygenic photosynthesis and aerobic methanotrophy.
Hunter, Ryan C.   +5 more
core   +3 more sources

Influence of the sebaceous gland density on the stratum corneum lipidome [PDF]

open access: yes, 2018
The skin surface lipids (SSL) result from the blending of sebaceous and epidermal lipids, which derive from the sebaceous gland (SG) secretion and the permeability barrier of the stratum corneum (SC), respectively.
Camera, Emanuela   +5 more
core   +1 more source

Squalene Emulsions for Parenteral Vaccine and Drug Delivery

open access: yesMolecules, 2009
Squalene is a linear triterpene that is extensively utilized as a principal component of parenteral emulsions for drug and vaccine delivery. In this review, the chemical structure and sources of squalene are presented.
Christopher B. Fox
doaj   +1 more source

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