Results 31 to 40 of about 42,005 (248)

Programmable Antigen‐Specific Immunity via Self‐Adjuvanting Nanovaccines Co‐Delivering Immune Modulators

open access: yesAngewandte Chemie, EarlyView.
The self‐adjuvanting vaccine—comprising a covalent conjugate of antigen and adjuvant—was formulated into cationic lipid nanoparticles smaller than 100 nm to facilitate uptake by immune cells, with supplemental adjuvants incorporated to modulate immune responses.
Keita Ito   +9 more
wiley   +2 more sources

Effects of graded levels of dietary squalene supplementation on the growth performance, plasma biochemical parameters, antioxidant capacity, and meat quality in broiler chickens

open access: yesPoultry Science, 2020
This study was conducted to evaluate the effects of dietary squalene supplementation on the growth performance, plasma biochemical indices, antioxidant status, and meat quality in broilers.
Yueping Chen   +4 more
doaj   +1 more source

Metabolic variables of cholesterol during squalene feeding in humans: comparison with cholestyramine treatment

open access: yesJournal of Lipid Research, 1990
Squalene, a key intermediate of cholesterol synthesis, is present especially in olive oil. Regulation of cholesterol metabolism by dietary squalene in man is unknown, even though olive oil users in Mediterranean areas have low serum cholesterol levels ...
TE Strandberg, RS Tilvis, TA Miettinen
doaj   +1 more source

Squalene Selectively Protects Mouse Bone Marrow Progenitors Against Cisplatin and Carboplatin-Induced Cytotoxicity In Vivo Without Protecting Tumor Growth

open access: yesNeoplasia: An International Journal for Oncology Research, 2008
Squalene, an isoprenoid antioxidant is a potential cytoprotective agent against chemotherapy-induced toxicity. We have previously published that squalene protects light-density bone marrow cells against cis-diamminedichloroplatinum( II) (cisplatin ...
Bikul Das   +9 more
doaj   +1 more source

Green Microalgae Strain Improvement for the Production of Sterols and Squalene

open access: yesPlants, 2021
Sterols and squalene are essential biomolecules required for the homeostasis of eukaryotic membrane permeability and fluidity. Both compounds have beneficial effects on human health. As the current sources of sterols and squalene are plant and shark oils,
Supakorn Potijun   +4 more
doaj   +1 more source

Relapse of polymyalgia rheumatica following adjuvanted influenza vaccine: A case-based review [PDF]

open access: yes, 2020
Polymyalgia rheumatica (PMR) is the most common inflammatory rheumatological condition affecting individuals aged >50 years. There have been rare reports of PMR and other vasculitides developing within 3 months of influenza vaccination.
Bassendine, Margaret F., Bridge, Simon
core   +1 more source

Determination of squalene in edible oils by transmethylation and GC analysis

open access: yesMethodsX, 2019
Squalene is a triterpenoid with medicinal, therapeutic and cosmetic applications. There is interest in identifying novel sources of squalene, creating a need for a rapid and accurate method of squalene determination.
Suzanne M. Budge, Christopher Barry
doaj   +1 more source

Ergosterol reduction impairs mitochondrial DNA maintenance in S. cerevisiae [PDF]

open access: yes, 2019
Sterols are essential lipids, involved in many biological processes. In Saccharomyces cerevisiae, the enzymes of the ergosterol biosynthetic pathway (Erg proteins) are localized in different cellular compartments.
Balliano, Gianni   +6 more
core   +2 more sources

Functional characterization of squalene synthase and squalene epoxidase in Taraxacum koksaghyz [PDF]

open access: yesPlant Direct, 2018
AbstractThe Russian dandelion Taraxacum koksaghyz produces high‐value isoprenoids such as pentacyclic triterpenes and natural rubber in the latex of specialized cells known as laticifers. Squalene synthase (SQS) and squalene epoxidase (SQE) catalyze key steps in the biosynthesis of cyclic terpenoids, but neither enzyme has yet been characterized in T ...
Unland, Kristina   +6 more
openaire   +2 more sources

Squalene synthase cloning and functional identification in wintersweet plant (Chimonanthus zhejiangensis)

open access: yesBotanical Studies, 2018
Background Three species of wintersweets: Chimonanthus salicifolius S. Y. Hu, Chimonanthus zhejiangensis M. C. Liu and Chimonanthus grammalus M. C. Liu are widely distributed in China.
Guanhua Liu, Jianyu Fu
doaj   +1 more source

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