Results 111 to 120 of about 44,786 (250)
A conserved NR5A1-responsive enhancer regulates SRY in testis-determination
Nature CommunicationsThe Y-linked SRY gene initiates mammalian testis-determination. However, how the expression of SRY is regulated remains elusive. Here, we demonstrate that a conserved steroidogenic factor-1 (SF-1)/NR5A1 binding enhancer is required for appropriate SRY ...
Denis Houzelstein +18 more
doaj +1 more source
Sex determination from dental pulp DNA among Egyptians
Egyptian Journal of Forensic Sciences, 2017 Background A great challenge arises when sex determination of human remains is needed, especially when only, bone fragments or isolated teeth are available; such as in mass disasters.
M. Kholief, S. El Shanawany, R. Gomaa
doaj +1 more source
"Human sex differentiation: From transcription factors to gender" [PDF]
, 2000 Amy B. Wiesniewski is an Assistant Professor of Biology at Drake University, Des Moines, Iowa. She can be contacted at amy.wisniewski@drake.eduOver the past decade, knowledge of the genetic control of human sex differentiation has greately expanded our ...
Migeon, Claude J., Wisniewski, Amy B.
core +2 more sources
Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?
Medicinal Research Reviews, EarlyView.ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca +6 more
wiley +1 more source
A case report of an XX male with complete masculinization but absence of the SRY gene
Middle East Fertility Society Journal, 2010 A 34-year old man with complete masculinization and a history of several years of infertility was referred to us for genetic reviewing. His semen analysis showed azoospermia.
Ghalia Abou Alchamat +2 more
doaj +1 more source
The Journal of Pathology, EarlyView.Abstract Canalicular adenoma (CA) is a benign salivary gland tumor predominantly affecting the upper lip and is characterized by monomorphic epithelial cells arranged in branching cords within a loose and vascularized stroma. Unlike pleomorphic adenoma (PA), CA lacks a chondroid matrix and exhibits specific histological features, such as high cuboidal ...
Ziyad Alsugair +8 more
wiley +1 more source
F1000Research, 2014 Recently, the sex determining region Y (Sry) and the cerebellar degeneration-related protein 1 (CDR1as) RNA transcripts have been described to function as a new class of post-transcriptional regulatory RNAs that behave as circular endogenous RNA sponges ...
Javier Tadeo Granados-Riveron +1 more
doaj +1 more source
Possible Pleiotropic Effect of SRY Gene May Increase Male Susceptibility to COVID-19. [PDF]
Am J Hypertens, 2021 Evangelho VGO +3 more
europepmc +1 more source
Stronger inflammatory/cytotoxic T cell response in women identified by microarray analysis [PDF]
, 2008 Women develop chronic inflammatory autoimmune diseases like lupus more often than men. The mechanisms causing the increased susceptibility are incompletely understood, although estrogen is believed to contribute.
Anura Hewagama +4 more
core +1 more source
Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis
Portal Hypertension &Cirrhosis, EarlyView.Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao +4 more
wiley +1 more source