Results 101 to 110 of about 44,786 (250)
Zfy genes are required for efficient meiotic sex chromosome inactivation (MSCI) in spermatocytes [PDF]
, 2016 During spermatogenesis, germ cells that fail to synapse their chromosomes or fail to undergo meiotic sex chromosome inactivation (MSCI) are eliminated via apoptosis during mid-pachytene.
Burgoyne, Paul S +4 more
core +3 more sources
PLoS ONE, 2014 BackgroundHealth assessment of the transplanted organ is very important due to the relationship of long-term survival of organ transplant recipients and health organ maintenance.
Hada C Macher +7 more
doaj +1 more source
Abnormal white matter tracts resembling pencil fibers involving prefrontal cortex (Brodmann area 47) in autism: a case report. [PDF]
, 2016 BackgroundAutism is not correlated with any neuropathological hallmark as the brain of autistic individuals lack defined lesions. However, previous investigations have reported cortical heterotopias and local distortion of the cytoarchitecture of the ...
Ariza, Jeanelle +4 more
core +1 more source
Vascular Calcification: Mechanisms, Models, and Therapies
iNew Medicine, EarlyView.ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu +5 more
wiley +1 more source
Molecular study of developmental sex disorders in children
Egyptian Journal of Medical Human Genetics, 2015 Background: Sex determination and differentiation in humans are processes that involve the interaction of several genes such as SRY, SOX9 genes which are important in the development of the male genital system.
Soheir S. AboElella +2 more
doaj +1 more source
MiR‐145‐5p Attenuates Doxorubicin‐Induced Heart Injury Through Targeting Cardiomyocyte Pyroptosis
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Doxorubicin (DOX), a potent anthracycline chemotherapeutic, exhibits dose‐dependent cardiotoxicity that limits its clinical utility. Although miR‐145‐5p demonstrates cardioprotective properties in cardiovascular diseases, its role in DOX‐induced cardiomyopathy remains undefined.
Xing‐Tao Chen +4 more
wiley +1 more source
Discovery of the human homolog of sex-determining region (SRY) gene in dioecious plants. [PDF]
Saudi J Biol Sci, 2023 Solliman ME +5 more
europepmc +1 more source
Testiculaire aandoening van seksuele differentiatie (78,XX SRY-negatief) bij een vrouwelijke Franse buldog [PDF]
, 2015 A presumably female intact French bulldog of ten months old was presented to the Faculty of Veterinary Medicine of the Ghent University with an enlarged clitoris and purulent vaginal discharge. It was suggested to remove the enlarged clitoris as to avoid
De Rooster, Hilde +6 more
core +1 more source
TALEN-mediated editing of the mouse Y chromosome [PDF]
, 2013 The functional study of Y chromosome genes has been hindered by a lack of mouse models with specific Y chromosome mutations. We used transcription activator-like effector nuclease (TALEN)-mediated gene editing in mouse embryonic stem cells (mESCs) to ...
A Mayer +26 more
core +1 more source
The Kaohsiung Journal of Medical Sciences, EarlyView.ABSTRACT Renal cell carcinoma (RCC) is a commonly occurring and considerable burden on public health. Although chemotherapy benefits patients with advanced RCC, sunitinib resistance leads to a poor prognosis. Ferroptosis is also involved in sunitinib resistance in RCC.
Yi‐Shuai Zhang +5 more
wiley +1 more source