Results 81 to 90 of about 44,786 (250)

Disturbed Ovarian Differentiation in XX;SRY-Negative Dogs [PDF]

, 2019
In a mammal, at the beginning of its development, the gonad is bipotential. The shift into a male or female pathway is coordinated by the sex chromosomal complement, which triggers a series of genetic pathways signaling the developmental pattern of the ...
Payan-Carreira, Rita
core   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

Specificity of Key Sex Determination Genes in a Mammal with Ovotestes: The European Mole Talpa europaea

Animals
Here, for the first time, the structure of genes involved in sex determination in mammals (full Sry and partial Rspo1, Eif2s3x, and Eif2s3y) was analyzed for the European mole Talpa europaea with ovotestes in females.
Alexey Bogdanov, Maria Sokolova, Irina Bakloushinskaya   +2 more
doaj   +1 more source

miR-638 is a new biomarker for outcome prediction of non-small cell lung cancer patients receiving chemotherapy. [PDF]

, 2015
MicroRNAs (miRNAs), a class of small non-coding RNAs, mediate gene expression by either cleaving target mRNAs or inhibiting their translation. They have key roles in the tumorigenesis of several cancers, including non-small cell lung cancer (NSCLC).
Cao, Yan, Huang, Pu-wen, Lou, Jian-fang, Pan, Shi-yang, Rao, Jian-yu, Shi, Xin-hui, Sun, Rui-hong, Wang, Fang, Wang, Hong, Wang, Peng, Xie, Er-fu, Xu, Jian, Xu, Ting   +12 more
core   +1 more source

Amplification of Porcine SRY Gene for Sex Determination

Asian-Australasian Journal of Animal Sciences, 2009
The separation of X and Y chromosome-bearing sperm is of use in many aspects of livestock maintenance. In this study, we sought to determine the difference in DNA content between X- and Y-bearing sperm, separate sperm into X- and Y-enriched pools, and assess the efficacy of sorting.
S. G. Choi, M. S. Bae, E. S. Lee, S. O. Kim, B. K. Kim, J. H. Yang, C. E. Jeon, H. H. Kim, Y. J. Hwang, E. S. Lee, D. Y. Kim   +10 more
openaire   +1 more source

WTAP‐Mediated m6A Modification Targets the LRP1‐Lipid Metabolism Axis to Regulate Joint Cartilage Regeneration

Advanced Science, EarlyView.
WTAP drives cartilage regeneration by activating an LRP1‐dependent lipid metabolic program in macrophages, enhancing IL‐10 and TGF‐β secretion to promote chondrogenic differentiation. Leveraging this mechanism, virtual screening identifies LRP1‐targeting compounds that effectively stimulate cartilage repair, highlighting a druggable epigenetic ...
Chenyan Huang, Chenyu Deng, Zhengrong Gao, Chen Chen, Huimin Zheng, Yue Yang, Yan Wei   +6 more
wiley   +1 more source

Sry delivery to the adrenal medulla increases blood pressure and adrenal medullary tyrosine hydroxylase of normotensive WKY rats

BMC Cardiovascular Disorders, 2007
Background Our laboratory has shown that a locus on the SHR Y chromosome increases blood pressure (BP) in the SHR rat and in WKY rats that had the SHR Y chromosome locus crossed into their genome (SHR/y rat).
Ciotti Mat, Bertram Jason, Milsted Amy, Ely Daniel, Dunphy Gail, Turner Monte E   +5 more
doaj   +1 more source

9q21.13q21.31 deletion in a patient with intellectual disability severe speech delay and and dysmorphic features a newly recognized microdeletion syndrome [PDF]

, 2019
The increased use of chromosomal microarray analysis has led to the identification of new microdeletion/microduplication syndromes, enabling better genotype-phenotype correlations.
Correia, Hildeberto, Ferreira, Cristina, Gonçalves, Rui, Marques, Barbara, Pedro, Sonia, Serafim, Silvia, Tarelho, Ana Rita   +6 more
core   +1 more source

Modern competency‐based teaching of human sexual development

Anatomical Sciences Education, EarlyView.
Abstract Embryology is an integral part of anatomy and a key subject in basic medical education. The development of the sexual tract, which is closely associated with the formation of the urinary tract and the organs of continence, is particularly complex and relevant for many medical disciplines.
Elisabeth Eppler, Alessandro Bilella, Christian M. Hammer   +2 more
wiley   +1 more source

Viability of human dental pulp in determination of sex of an individual by identifying srygene through DNA analysis: A single blind pilot study

Journal of Indian Academy of Oral Medicine and Radiology, 2012
Recognition of importance of human teeth in personal identification has been recognized from time immemorial. In any natural calamity or man-made catastrophe identification of an individual is of paramount importance.
Prachi Ravikant Naik, Deepa Das Acath, Gapal H Sharma, Amita Rahul Navalkar   +3 more
doaj   +1 more source