Results 111 to 120 of about 6,330 (191)

Lactobacillus paracasei Reduces Intestinal Inflammation in Adoptive Transfer Mouse Model of Experimental Colitis

Clinical and Developmental Immunology, 2011
Studies showed that specific probiotics provide therapeutic benefits in inflammatory bowel disease. In vitro evidence suggested that Lactobacillus paracasei also called ST11 (CNCM I-2116) is a potent strain with immune modulation properties.
Manuel Oliveira, Nabil Bosco, Genevieve Perruisseau, Jeanne Nicolas, Iris Segura-Roggero, Stéphane Duboux, Muriel Briand, Stéphanie Blum, Jalil Benyacoub   +8 more
doaj   +1 more source

blaKPC-2 amplification and a novel mrcA mutation drive cefiderocol heteroresistance in ST11 CRKP

International Journal of Antimicrobial Agents
Cefiderocol (FDC) is a promising treatment for infections caused by carbapenem-resistant Klebsiella pneumoniae (CRKP), but emerging heteroresistance (HR) may compromise its clinical efficacy. This study aimed to elucidate the molecular mechanisms underlying FDC heteroresistance arising during in vivo evolution of CRKP.
Yuxuan Liu, Hanxu Hong, QianBin Dai, Linping Fan, Peng Liu, DanDan Wei, Yang Liu   +6 more
openaire   +2 more sources

Multiple Benefits of Plasmid-Mediated Quinolone Resistance Determinants in Klebsiella pneumoniae ST11 High-Risk Clone and Recently Emerging ST307 Clone [PDF]

, 2019
International high-risk clones of Klebsiella pneumoniae are among the most common nosocomial pathogens. Increased diversity of plasmid-encoded antimicrobial resistance genes facilitates spread of these clones causing significant therapeutic difficulties.
Ivelina Damjanova, Judit Domokos, Dora Szabo, Bela Kocsis, Katalin Kristof, Balazs Ligeti   +5 more
core   +1 more source

Epidemiological, phenotypic and genotypic characteristics difference of hypervirulent and carbapenem-resistant Klebsiella pneumoniae with different capsular serotypes

Journal of Microbiology, Immunology and Infection
Background: KL1, KL2 CR-hvKP and KL64, KL47 hv-CRKP all exhibit overlapping multidrug resistance and hypervirulence phenotypes, but the differences in epidemiological, phenotypic and genotypic characteristics between them remains unclear.
Cong Zhou, Wencai Ke, Hui Zhang, Maosuo Xu, Baoyu Yuan, Yong Lin, Fang Shen   +6 more
doaj   +1 more source

Emergence and regional evolution of Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae ST11 in China

BMC Genomics
Klebsiella pneumoniae carbapenemase (KPC)-producing K. pneumoniae (KPC-KP) sequence type (ST) 11 has emerged as a significant public health threat in China, yet its endemic population and evolutionary dynamics remain incompletely understood. To address this, we investigated the national distribution and local evolution of KPC-KP ST11 in China.Our ...
Ma, Zheng, Mo, Li, Hu, Jihua, Qu, Jiuxin, Cao, Huiluo, Jiang, Shuo   +5 more
openaire   +2 more sources

Increase in antioxidant capacity associated with the successful subclone of hypervirulent carbapenem-resistant Klebsiella pneumoniae ST11-KL64 [PDF]

The acquisition of exogenous mobile genetic material imposes an adaptive burden on bacteria, whereas the adaptational evolution of virulence plasmids upon entry into carbapenem-resistant Klebsiella pneumoniae (CRKP) and its impact remains unclear.
Zhang, Yawei, Yin, Guankun, Wu, Xingyu, Chen, Fengning, Wang, Shuyi, Van Dorp, Lucy, Wang, Hui, Sun, Shijun, Wang, Ruobing, Jin, Longyang, Zhang, Anru, Wang, Qi, Ding, Qi, Balloux, Francois, Wang, Xiaojuan   +14 more
core   +1 more source

First description of qnrS1-IncN plasmid in a ST11 Salmonella Enteritidis clinical isolate from Portugal

, 2011
The presence of qnr and qepA genes was investigated among 300 nontyphoidal Salmonella showing decreased susceptibility to ciprofloxacin obtained from different sources in Portugal (2002–2004). The qnrS1 gene was located within a conjugative IncN plasmid
Peixe, Luisa, Patrícia Antunes, Luísa Peixe, Jorge Machado, Machado, Jorge, Antunes, Patricia, Joana Mourão, Mourão, Joana   +7 more
core   +1 more source

Genomic characterization of ST11-KL25 hypervirulent KPC-2-producing multidrug-resistant Klebsiella pneumoniae from China

Summary: The global prevalence of ST11 hypervirulent carbapenem-resistant Klebsiella pneumoniae (hv-CRKP) isolates has been increasingly documented, yet genomic characterization of this clone remains insufficiently explored.
Yuting Kang, Wanting Ma, Wei Jia, Qiujie Li, Chao Xu, Pengtao Wang   +5 more
core   +1 more source

ST11 KPC-2-Producing Klebsiella pneumoniae Isolated from Patient with Acute Myelocytic Leukemia

Infection and Drug Resistance
The emergence of the ST11-CRKP (ST11-CRKP) strain is expected to become a serious public health problem in China. As one of the most serious complications in patients with acute myeloid lymphoma, infections can cause systemic infection and life-threatening sepsis, seriously affecting the morbidity, mortality, and quality of life of patients. Thus, ST11-
Can Chen, Fan Yang, Mantao Chen, Ying Xu, Yaping Xie, Ruishan Liu, Pengfei Shi, Shenxian Qian   +7 more
openaire   +4 more sources

Molecular epidemiology and resistome analysis of multidrug-resistant ST11 Klebsiella pneumoniae strain containing multiple copies of extended-spectrum β-lactamase genes using whole-genome sequencing [PDF]

, 2017
The aim of this work was to investigate the mechanism responsible for multidrug resistance in ST11 Klebsiella pneumoniae YMC 2013/7/B3993 containing multiple copies of ESBL genes using multiple parallel sequencing technology.
용동은, 이경원, 최종락
core