Results 81 to 90 of about 1,621 (161)

Identification of immune infiltration and PANoptosis‐related molecular clusters and predictive model in Alzheimer's disease based on transcriptome analysis

Ibrain, Volume 10, Issue 3, Page 323-344, Fall 2024.
Based on R, immune infiltration analysis found that normal and disease immune cells expressed differently, weighted gene co‐expression network analysis determined the key genes of diseases and clustering, and eXtreme Gradient Boosting model screened Hub genes. Abstract This study aims to explore the expression profile of PANoptosis‐related genes (PRGs)
Jin‐Lin Mei, Shi‐Feng Wang, Yang‐Yang Zhao, Ting Xu, Yong Luo, Liu‐Lin Xiong   +5 more
wiley   +1 more source

Advances in understanding the pathogenesis of epilepsy: Unraveling the molecular mechanisms

Health Science Reports, Volume 7, Issue 2, February 2024.
Abstract Introduction Epilepsy is characterized by having two or more unprovoked seizures. Understanding the pathogenesis of epilepsy, requires deep investigation into the molecular mechanisms. This helps develop diagnostic techniques, treatments, and pharmacotherapy. It also enhances precision medicine and individualized treatment processes.
Sanobar Shariff, Halah A. Nouh, Samuel Inshutiyimana, Charbel Kachouh, Maya M. Abdelwahab, Abubakar Nazir, Magda Wojtara, Olivier Uwishema   +7 more
wiley   +1 more source

Transmembrane α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor regulatory protein expression during the development of absence seizures in genetic absence epilepsy rats from Strasbourg

Epilepsia, Volume 65, Issue 2, Page e20-e26, February 2024.
Abstract The transmembrane α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor (AMPAR) regulatory proteins (TARPs), γ2 (stargazin), γ3, γ4, γ5, γ7, and γ8, are a family of proteins that regulate AMPAR trafficking, expression, and biophysical properties that could have a role in the development of absence seizures.
Pablo M. Casillas‐Espinosa, Runxuan Lin, Rui Li, Kim L. Powell, Terence J. O'Brien   +4 more
wiley   +1 more source

Aberrant hippocampal transmission and behavior in mice with a stargazin mutation linked to intellectual disability [PDF]

, 2021
GL Caldeira, AS Inácio, Nuno Beltrão, CAV Barreto, MV Rodrigues, Tiago Rondão, R. Macedo, RP Gouveia, Mohamed Edfawy, Joana R. Guedes, Benjamin Dela Cruz, SR Louros, Irina S. Moreira, João Peça, Ana Luı́sa Carvalho   +14 more
openalex   +1 more source

Enhanced AMPAR-dependent synaptic transmission by S-nitrosylation in the vmPFC contributes to chronic inflammatory pain-induced persistent anxiety in mice. [PDF]

Acta Pharmacol Sin, 2023
Chen ZJ, Su CW, Xiong S, Li T, Liang HY, Lin YH, Chang L, Wu HY, Li F, Zhu DY, Luo CX.   +10 more
europepmc   +1 more source

Molecular Mechanisms of AMPA Receptor Trafficking in the Nervous System. [PDF]

Int J Mol Sci, 2023
Cao YY, Wu LL, Li XN, Yuan YL, Zhao WW, Qi JX, Zhao XY, Ward N, Wang J.   +8 more
europepmc   +1 more source

New role for spinal Stargazin in α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor‐mediated pain sensitization after inflammation [PDF]

, 2006
Feng Tao, John Skinner, Qingning Su, Roger A. Johns   +3 more
openalex   +1 more source

Interactome of stargazin: relevance in neuropsychiatric disorders

, 2016
Dissertação de Mestrado em Biologia Celular e Molecular apresentada à Faculdade de Ciências e Tecnologia da Universidade de Coimbra.
openaire   +1 more source

Nondisruptive inducible labeling of ER-membrane contact sites using the Lamin B receptor. [PDF]

PLoS Biol
Downie L, Ferrandiz N, Courthold E, Jones M, Royle SJ.   +4 more
europepmc   +2 more sources

AMPA receptors and stargazin-like transmembrane AMPA receptor-regulatory proteins mediate hippocampal kainate neurotoxicity

, 2007
Susumu Tomita, R. Keith Byrd, Nathalie Rouach, Camilla Bellone, Ángela Venegas, Jessica L. O'Brien, Kwang S. Kim, Olav Olsen, Roger A. Nicoll, David S. Bredt   +9 more
openalex   +1 more source