Results 151 to 160 of about 29,695 (266)

The Interplay of M1 Macrophages and Dental Pulp Stem Cells Promotes Angiogenesis Through IL‐8‐Dependent VEGF Regulation: An In Vitro Study

International Endodontic Journal, Volume 59, Issue 10, Page 2143-2163, October 2026.
ABSTRACT Background Dental pulp inflammation triggers immune responses involving macrophages and dental pulp stem cells (DPSCs), which interact to regulate angiogenesis essential for tissue repair. M1 pro‐inflammatory macrophages predominate early in pulpitis, and clarifying their angiogenic role is vital in identifying inflammatory regenerative ...
Dineshi Sewvandi Thalakiriyawa, Mohamad Koohi‐Moghadam, Mingxin Hu, Hong Wang, Colman McGrath, Waruna Lakmal Dissanayaka   +5 more
wiley   +1 more source

Cancer cell‐intrinsic type 1 interferon: production, signaling, and outcomes within sex‐biased, female malignancies

Molecular Oncology, Volume 20, Issue 9, Page 2135-2162, September 2026.
The cell‐autonomous roles of interferon type 1 vary based on duration and intensity. While acute, robust signaling results in cancer cell cytotoxic effects, sustained, low‐level signaling is associated with tumor‐promoting effects. This review summarizes current research of IFN‐1 in cancer and within the clinical setting, with an emphasis on female ...
Ashlyn Conant, Nora Badiner, Sharon Asariah, Kiera McGivney, Vishwa Shah, Tise Suzuki, Yevgeniya J. Ioffe, Juli J. Unternaehrer   +7 more
wiley   +1 more source

An Integrative Strategy Delineates Modular Metabolic Remodeling and Potential Therapeutic Targets Across Metabolic Diseases

Advanced Science, Volume 13, Issue 52, 18 September 2026.
An integrative single‐cell atlas across multiple metabolic diseases reveals coordinated metabolic modules and disease‐shared versus disease‐specific pathway activities. By systematically comparing scoring strategies, a robust RankAve framework is established. Coupled with network analysis and drug‐target prediction, this resource uncovers cross‐disease
Kuan Yang, Congxue Hu, Hang Zhao, Xiao Peng, Yiming Yan, Jiasi Wang, Wenqi Jiang, Depeng Mu, Yan Cao, Xia Li, Yunpeng Zhang   +10 more
wiley   +1 more source

Solitary Fibrous Tumor of the Mesentery of the Small Intestine: A Rare Case Report

Journal of the Anus, Rectum and Colon
Solitary fibrous tumors (SFTs) are rare spindle cell neoplasms of mesenchymal origin, most commonly originating from the pleura. The discovery of the NAB2-STAT6 gene fusion has enabled more accurate diagnosis, particularly in extrapleural locations.
Go Ito, Katsuya Hattori, Yasunori Ota, Junko Mukohyama, Naoki Sakuyama, Dai Shida   +5 more
doaj  

Regulation of the Dephosphorylation of Stat6 [PDF]

Journal of Biological Chemistry, 2003
Erica M. Hanson, Harold Dickensheets, Cheng-Kui Qu, Raymond P. Donnelly, Achsah D. Keegan   +4 more
openaire   +1 more source

Nucleocytoplasmic Transport of the Transcription Factor STAT6

Signal Transducer and Activator of Transcription 6 (STAT6) is a member of the STAT family of transcription factors that regulate cytokine signaling pathways.
Chen, Hui-Chen
core  

Neurobiological mechanisms of 40‐Hz stimulation in Alzheimer's disease: evidence, heterogeneity, and constraints

Alzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract Early disruption of gamma oscillations is increasingly recognized as a contributor to neurodegeneration and cognitive decline in Alzheimer's disease (AD), positioning 40‐Hz stimulation as a promising neuromodulatory strategy. However, its neurophysiological and cognitive effects remain highly variable across studies, underscoring the need for ...
Lin Qi, Weiye Wang, Reema Abdullah, Yilei Zhao, Zhibin Wang, Yi Tang, Benyan Luo, Guoping Peng   +7 more
wiley   +1 more source

Acupuncture for Poststroke Dysphagia: An NTS‐Centered Hypothesis‐Generating Framework Linking the Brainstem Swallowing Network, Neuroimmune Regulation, and Vagal Anti‐Inflammatory Signaling

Brain and Behavior, Volume 16, Issue 9, September 2026.
ABSTRACT Background Poststroke dysphagia (PSD) may reflect not only focal motor pathway injury but also instability of the brainstem swallowing network under neuroimmune, glial, and vascular microenvironmental stress. Methods This mechanism‐oriented narrative review synthesized evidence on swallowing central pattern generator (CPG) organization ...
Wei Li, Lebin Liu, Yingying Tu, Chongjiu Gong, Xiao Ran, Jiuguo Pei   +5 more
wiley   +1 more source

Impact of STAT6 Variants on the Response to Proton Pump Inhibitors and Comorbidities in Patients with Eosinophilic Esophagitis

Proton pump inhibitors (PPIs) are the first-line drug for eosinophilic esophagitis (EoE), although it is estimated that there is a lack of histological remission in 50% of patients. This research aimed to identify pharmacogenetic biomarkers predictive of
Majano, Pedro, Soria Chacartegui, Paula, Lucendo, Alfredo J., Navares Gómez, Marcos, Molina Jiménez, Francisca, Marcos Navares-Gómez, Abad Santos, Francisco, Zubiaur Precioso, Pablo, Santander Vaquero, Cecilio, Francisca Molina-Jiménez, Pedro Majano, Cecilio Santander, Paula Soria-Chacartegui, Laura Arias-González, Majano Rodríguez, Pedro Lorenzo, Molina-Jiménez, Francisca, Sergio Casabona, Zubiaur, Pablo, Laserna Mendieta, Emilio J., Casabona, Sergio, Santander, Cecilio, Emilio J. Laserna-Mendieta, Arias-González, Laura, Francisco Abad-Santos, Pablo Zubiaur, Alfredo J. Lucendo, Arias González, Laura, Navares-Gómez, Marcos, Laserna-Mendieta, Emilio J.   +28 more
core   +1 more source

STAT6 and STAT4 in murine atherosclerosis

, 2013
Atherosclerosis is a chronic inflammatory condition and the major underlying cause of heart attacks and strokes. Since the immune system is paramount in all stages of atherosclerosis, modulating the immune response is an attractive therapeutic strategy for atherosclerotic disease.
openaire   +1 more source