Results 151 to 160 of about 30,689 (278)
Figure 1. T. gondii inhibited the expressions of Trem2 and its downstream effectors. (A) Representative images of uteri and fetuses at G 17.5 in PBS and T. gondii-infected WT mice.
Cao, Y (via Mendeley Data), Cao, Yining
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Synergistic Regulation of Biomaterials and Macrophages: A Novel Paradigm in Immunotherapy
MedComm – Biomaterials and Applications, Volume 5, Issue 4, December 2026.Bioengineered materials mediating the modulation of macrophage plasticity and inflammatory signals in the tumor microenvironment effectively remodel immunoregulatory states, boost antitumor immunity, and promote tissue repair, achieving synergistic therapeutic outcomes.
Jiayu Zhang +16 more
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Glia, Volume 74, Issue 11, November 2026.Relapsing colitis region‐specific microglial states beyond remission. Cortical microglia remain pro‐inflammatory and synapse‐disruptive, while hippocampal microglia shift toward a reparative program that maintains neuronal circuit stability. ABSTRACT Ulcerative colitis (UC) patients experience cycles of active gut inflammation and remission, with ...
Lorena Morton +6 more
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MedComm, Volume 7, Issue 11, November 2026.Efferocytosis is a key process for macrophages to clear apoptotic cells, which undergoes the “ Find Me” chemotaxis signal stage, the “eat me” phagocytosis recognition stage and the “digest me” digestion stage in turn. During the aforementioned three stages, various signaling molecules released by apoptotic cells can promote the phenotypic polarization ...
Qiuping Chen +3 more
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Regulation of the Dephosphorylation of Stat6 [PDF]
Journal of Biological Chemistry, 2003 Erica M. Hanson +4 more
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STAT6 and Its Relationship with PSA and Annexin A2 in Human Prostate Cancer [PDF]
, 2014 Roth, Cherice, STAT6 and its relationship with PSA and Annexin A2 in Human Prostate Cancer. Master of Science (Biochemistry and Molecular Biology), May 2008, 49 pages, 13 illustrations, reference list, 54 titles.
Roth, Cherice P.
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MedComm, Volume 7, Issue 11, November 2026.This comprehensive review summarizes gastric cancer epidemiology, multifactorial risk factors (like infectious, dietary, genetic), pathogenesis such as precancerous evolution, molecular alterations, and a focus on the bidirectional interactions between gastric cancer cells and macrophages in the tumor microenvironment.
Yixuan Xin +6 more
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4‐1BBL Suppresses Anti‐Inflammatory Responses by Regulating Metabolic Reprogramming of Macrophages
Immunology, Volume 179, Issue 3, Page 434-443, November 2026.4‐1BB ligand (4‐1BBL) is known to promote sustained pro‐inflammatory responses in macrophages. This study demonstrates that 4‐1BBL acts as a negative regulator of anti‐inflammatory macrophage responses. Genetic deletion or pharmacological inhibition of 4‐1BBL significantly enhanced the phosphorylation of IL‐4R‐proximal JAK1 and STAT6, elevating the ...
Young Jun Kang
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STAT6 and STAT4 in murine atherosclerosis
, 2013 Atherosclerosis is a chronic inflammatory condition and the major underlying cause of heart attacks and strokes. Since the immune system is paramount in all stages of atherosclerosis, modulating the immune response is an attractive therapeutic strategy for atherosclerotic disease.
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Journal of Cellular and Molecular Medicine, Volume 30, Issue 21, November 2026.ABSTRACT Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS) is a condition marked by persistent inflammation of the prostate, whose underlying mechanisms remain poorly defined. This study aimed to investigate the role of prostaglandin‐endoperoxide synthase 1 (PTGS1) in macrophages and in a mouse model of experimental autoimmune prostatitis (EAP)
Jian Song +7 more
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