Results 161 to 170 of about 29,695 (266)

The Significance of cGAS‐STING Signaling in Response to Oncogenic Viruses

Cell Biochemistry and Function, Volume 44, Issue 9, September 2026.
ABSTRACT The cyclic GMP‐AMP synthase (cGAS)‐stimulator of interferon genes (STING) signaling pathway, as a key DNA sensor, plays a significant role in the regulation of innate immune responses. This pathway can be activated by sensing abnormal DNA, and is of great significance for resisting the invasion of pathogenic microorganisms and maintaining ...
Limei Guo, Li Li, Fang Wang, Wen Liu, Yan Zhang   +4 more
wiley   +1 more source

Neurofibromatosis Type 1 Tumor Involving the Anterosuperior Mediastinum With a Rare c.147C>G Germline Mutation: A Case Report

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Neurofibromatosis type 1 (NF1) is an autosomal dominant disorder that affects multiple organ systems, most commonly the skin, peripheral nerves, and skeletal system. However, involvement of the anterior mediastinum is rare and has been sporadically reported in the literature.
Yuhao Qi, Shenghai Wang, Zhaokun Sun, Jianhua Du, Jun Li   +4 more
wiley   +1 more source

STAT6 Gene [PDF]

, 2020
openaire   +1 more source

Cytodiagnostic features of angiofibroma of soft tissue: A review of 16 cases to identify characteristic findings and their diagnostic significance

Cancer Cytopathology, Volume 134, Issue 9, September 2026.
Abstract Background Angiofibroma of soft tissue (AFST) is a rare benign fibroblastic/myofibroblastic neoplasm. Despite several published studies describing the clinicopathological features of AFSTs, its cytological characteristics remain poorly documented. This study aimed to identify distinctive cytological features that may support accurate diagnosis.
Takahiko Ito, Kyoko Yamashita, Koichi Ikebata, Satoko Baba, Yuki Togashi, Akito Dobashi, Keisuke Ae, Seiichi Matsumoto, Kengo Takeuchi, Hitoshi Abe, Tomohiro Chiba   +10 more
wiley   +1 more source

STAT6 is epigenetically down-regulated in glioma and regulates cell viability

, 2014
DNA hypermethylation-induced silencing of tumor suppressor is a well-recognized mechanism of epigenetic modification which occurs human tumors. In this study, we demonstrated that the transcription factor STAT6 was markedly down-regulated in glioma ...
Jou, Ilo, Park, Soo Jung
core   +1 more source

Regulation of STAT6 and STAT4 Phosphorlation by Histamine

, 2006
Signal transducer and activators of transcription (STAT) - 6 and STAT4 are the transcriptional factors crucial for the T helper cell differentiation into Thl and Th2 respectively.
Kharmate, Geetanjali
core  

Exosomal PSMD1 Derived From Dental Pulp Mesenchymal Stem Cells Promotes Microglial M2 Polarization to Alleviate Spinal Cord Injury

CNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
DPMSCs‐derived exosomal PSMD1 stimulates M2 polarization through the JAK2/STAT3 pathway. DPMSCs‐derived exosomal PSMD1 indirectly acts on NE‐4C cells. DPMSCs‐derived exosomal PSMD1 ameliorates SCI in a mouse model. ABSTRACT Background Exosomes derived from mesenchymal stem cells (MSCs) and their cargo contribute to the protective properties of MSCs in ...
Xiaohui Xing, Yuan Hao, Guanghui Zhang, Xiaoyang Xing, Hongfei Jia, Chenlong Liu, Xin Wang, Tao Li, Xueyuan Li, Yilei Xiao   +9 more
wiley   +1 more source

Microglia and neuroinflammation: An in‐depth analysis from functional diversity to disease mechanisms

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
1. Microglial functions arise from dynamic, context‐dependent programs rather than fixed M1/M2 phenotypes. 2. Inflammatory, interferon‐responsive, phagocytic/lipid‐metabolic and repair‐associated programs coexist across disease stages and brain regions. 3.
Jie Chen, Wangzheqi Zhang, Lizhou Song, Yan Liao, Haoling Zhang, Yiyang Xia, Derong Cui   +6 more
wiley   +1 more source

PDLIM4 promotes dephosphorylation of STAT transcription factors by recruiting PTP-BL and inhibits Th1, Th2, and Th17 cell differentiation. [PDF]

Int Immunol
Jodo A, Nakahira M, Kochi Y, Sugimoto-Ishige A, Kaisho T, Tanaka T.   +5 more
europepmc   +1 more source

Herbal Extracts and Plant‐Derived Bioactives in Atopic Dermatitis: Evidence, Mechanisms, Pediatric Safety, and Translational Priorities

Food Science &Nutrition, Volume 14, Issue 9, September 2026.
Food‐derived bioactives, herbal extracts, and standardized botanical products are being investigated as adjunctive strategies for atopic dermatitis. Their biological activity is shaped not only by plant source and nominal dose, but also by fermentation, drying, heating, extraction, food‐matrix binding, gastrointestinal transformation, and formulation ...
Muhuang Zeng, Qianlan Yuan, Shuojia Huang, Xiaofei Lu   +3 more
wiley   +1 more source