Results 1 to 10 of about 160,250 (217)
Abstract Purpose of Review Hematopoietic stem cells (HSCs) are formed embryonically during a dynamic developmental process and later reside in adult hematopoietic organs in a quiescent state.
Teresa V. Bowman, Eirini Trompouki
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Stem cells are unique in their capacity to self-renew and generate differentiated progeny to maintain tissues throughout life. A common molecular program for stem cells has remained elusive. We discuss what the molecular logic of stemness may be. We suggest that it may not be coupled to distinct cellular properties such as self-renewal or multipotency,
Harald, Mikkers, Jonas, Frisén
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Stem cells are self-renewing cells capable of differentiating into multiple cell lines and are classified according to their origin and their ability to differentiate. Enormous potential exists in use of stem cells for regenerative medicine. To produce effective stem cell-based treatments for a range of diseases, an improved understanding of stem cell ...
Björn, Behr +4 more
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Improving science, technology, engineering, and mathematics (STEM) education, especially for traditionally disadvantaged groups, is widely recognized as pivotal to the United States's long-term economic growth and security. In this article, we review and discuss current research on STEM education in the United States, drawing on recent research in ...
Xie, Yu +2 more
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Two converging events took place on 9 August that ought to have the scientific community scratching its collective head. One of these is an anniversary: On that date in 2001, President George W. Bush signed an Executive Order banning any use of federal funds to support research on stem cells (save, of course, for those 78 preexisting cell lines, only ...
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Research interdisciplinarity: STEM versus non-STEM [PDF]
Research collaboration among interdisciplinary teams has become a common trend in recent days. However, there is a lack of evidence in literature regarding which disciplines play dominant roles in interdisciplinary research settings. It is also unclear whether the dominant role of disciplines vary between STEM (Science, Technology, Engineering, and ...
Shahadat Uddin +2 more
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Stemming vision loss with stem cells [PDF]
Dramatic advances in the field of stem cell research have raised the possibility of using these cells to treat a variety of diseases. The eye is an excellent target organ for such cell-based therapeutics due to its ready accessibility, the prevalence of vasculo- and neurodegenerative diseases affecting vision, and the availability of animal models to ...
Valentina, Marchetti +3 more
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Stemness, cancer, and cancer stem cells [PDF]
The ability of cancers to grow indefinitely has fueled the idea that cancer and stem cells may have common underlying mechanisms. Detailed gene expression maps have now shown the diversity and distinctiveness in gene expression programs associated with stemness in embryonic and adult stem cells. These maps have further revealed a shared transcriptional
David J, Wong +2 more
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Coherent poly propagation materials with 3-dimensional photonic control over visible light.
The purpose of the present research was to identify and examine materials demonstrating a previously undiscovered property of coherent poly propagation (CPP). The materials were amorphous silicates as natural precious opals. CPP enabled three-dimensional
Michelle R Stem
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Hematopoietic stem cell metabolism and stemness
AbstractHematopoietic stem cells (HSCs) are considered to originate from the aorta-gonad-mesonephros, migrate into fetal liver for a rapid expansion, and eventually reside into a unique hypoxic bone marrow niche, where they maintain their homeostasis throughout their life span.
Dan Huang +4 more
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