ETS1–EGR2 facilitates renal cell carcinoma progression by activating NOTCH signalling
Clinical and Translational Medicine, Volume 16, Issue 8, August 2026.ETS1 expression is significantly higher in ccRCC samples, and ETS1‐overexpression increases RCC cell malignancies in vitro and tumour growth in nude mice. ETS1 binds to EGR2 and destabilises EGR2 protein, which relieves EGR2's inhibitory effect on NOTCH signalling. NOTCH signalling activation promotes RCC development.
Weifeng Ye +6 more
wiley +1 more source
Do dental stem cells depict distinct characteristics? - Establishing their "phenotypic fingerprint"
Dental Research Journal, 2014 Dental tissues provide an alternate source of stem cells compared with bone marrow and have a similar potency as that of bone marrow derived mesenchymal stem cells. It has been established there are six types of dental stem cells: Dental pulp stem cells,
Deepa Ponnaiyan
doaj
Macromolecular Bioscience, Volume 26, Issue 8, August 2026.Hybrid PLGA–corneal ECM biomembrane for ocular progenitor cell support and progenitor retinal cytoprotection. A hybrid biomembrane composed of PLGA and decellularized corneal extracellular matrix was developed to create a biomimetic microenvironment for ocular progenitor cells.
Ana Karulline Garcia Ungaratti +7 more
wiley +1 more source
Mitochondrial Functions Maintain Scap Survival Following P. Endodontalis Infection
International Dental JournalAim or purpose: To investigate the effects of Porphyromonas endodontalis on the viability of stem cells from the apical papilla (SCAP) and explore the mechanism of mitochondrial functions and downstream signalling in maintaining SCAP survival, thus to ...
Xu Chen, Shuang Lei
doaj +1 more source
Formation of Three-Dimensional Spheres Enhances the Neurogenic Potential of Stem Cells from Apical Papilla. [PDF]
Bioengineering (Basel), 2022 Basabrain MS +8 more
europepmc +1 more source
TAXON, Volume 75, Issue 4, August 2026.Abstract The genus Kartalinia was described to accommodate a single, obscure species, Psoralea acaulis, based on its unique morphology and karyology. No concerted molecular phylogenetic studies were available for this species at the time, and therefore its phylogenetic position was uncertain.
Brian Du Preez +4 more
wiley +1 more source
In-vitro Evaluation for Effects of Intracanal Medicaments on Viability, Proliferation, and Differentiation of Stem Cells From Apical Papilla - A Systematic Review. [PDF]
Eur Endod J, 2022 Rahul M +6 more
europepmc +1 more source
Single‐Cell Virtual Perturbation Screening Identifies STAT3 as a Key Regulator of Dentinogenesis
Cell Proliferation, Volume 59, Issue 8, August 2026.STAT3 promotes odontoblast differentiation in dental mesenchymal cells by transcriptionally regulating WNT2B via the canonical Wnt/β‐catenin signalling pathway. These findings elucidate a mechanism underlying dentine development. ABSTRACT Dentine formation constitutes a physiological process precisely regulated by signal transduction modules governing ...
Yanfei Zhu +12 more
wiley +1 more source
Simvastatin Induces Apoptosis but Attenuates Migration in SCAPs
International Dental Journal: Aim: Simvastatin has emerged as having a promising role in controlling stem cell behaviours. This study aimed to evaluate the effects of simvastatin on the viability, growth, and migration of stem cells isolated from apical papillae (SCAPs) in vitro ...
Paak Rewthamrongsris +4 more
doaj +1 more source
MiR-199a-5P promotes osteogenic differentiation of human stem cells from apical papilla via targeting IFIT2 in apical periodontitis. [PDF]
Front Immunol, 2023 Hu J +7 more
europepmc +1 more source