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Differential Circular RNA Expression Profiling During Osteogenic Differentiation of Stem Cells from Apical Papilla

Epigenomics, 2019
Aim: This study aimed to investigate the distinct expression pattern of circular RNAs (circRNAs) in stem cells from apical papilla (SCAPs) during osteogenesis. Materials & methods: Isolated SCAPs were cultured in growth medium or osteogenic medium, respectively. Total RNA was extracted and submitted to RNA-sequencing.
Zehan, Li   +7 more
openaire   +2 more sources

SFRP2 enhanced the adipogenic and neuronal differentiation potentials of stem cells from apical papilla

Cell Biology International, 2017
AbstractDental tissue‐derived mesenchymal stem cells (MSCs) are easily obtained and considered as a favorable cell source for tissue engineering, but the regulation of direct differentiation is unknown, which restricts their application. The present study investigated the effect of SFRP2, a Wnt signaling modulator, on MSC differentiation using stem ...
Xiao, Lin   +6 more
openaire   +2 more sources

[Human stem cells from apical papilla can regenerate dentin-pulp complex].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2014
To regenerate dentin-pulp complex by tissue engineering with human stem cells from apical papilla cells (SCAP) as the seed cells.SCAP was separated from from normal human impacted third molars with immature roots by outgrowth culture. The cells were then cultured in the differentiation medium for 3 weeks or in normal medium for 60 days, and analyzed ...
Huacui, Xiong   +3 more
openaire   +1 more source

Lineage Differentiation of Mesenchymal Stem Cells from Dental Pulp, Apical Papilla, and Periodontal Ligament

2012
Recently, a variety of mesenchymal stem cells (MSCs), including dental pulp stem cells, stem cells from human exfoliated deciduous teeth, stem cells from apical papilla, periodontal ligament stem cells, and mesenchymal stem cells derived from human gingival, were isolated from orofacial and dental tissues. However, it is unknown whether these orofacial
Akiyama, K.   +3 more
openaire   +3 more sources

Circ‐ZNF236 mediates stem cells from apical papilla differentiation by regulating LGR4‐induced autophagy

International Endodontic Journal
AbstractAimHuman stem cells from the apical papilla (SCAPs) are an appealing stem cell source for tissue regeneration engineering. Circular RNAs (circRNAs) are known to exert pivotal regulatory functions in various cell differentiation processes, including osteogenesis of mesenchymal stem cells.
Ya Xiao   +11 more
openaire   +2 more sources

[Isolation, culture and biological characterization of Beagle stem cells from apical papilla].

Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2014
To isolate and characterize the Beagle stem cells from apical papilla.Apical papilla was severed from the end of freshly extracted Beagle's young permanent upper anterior teeth, and digested by collagenase type I and dispase for cell culture. The isolated cells were investigated for stem cell properties by analyzing their colony-forming efficiency ...
Jie, Yang   +4 more
openaire   +1 more source

Neuroregenerative Potential of Stem-Cells-from-Apical-Papilla–Derived Neuronal Cell Spheroids Regulated by Stem Cells from Apical Papillae Under Various Microenvironments in a Pulp-On-Chip System

Journal of Endodontics, 2022
Haiyun Luo   +7 more
openaire   +1 more source

A single‐cell transcriptomic atlas of human stem cells from apical papilla during the committed differentiation

International Endodontic Journal
AbstractAimHuman stem cells derived from the apical papilla (SCAPs) are recognized for their multilineage differentiation potential and their capacity for functional tooth root regeneration. However, the molecular mechanisms underlying odonto/osteogenic differentiation remain largely unexplored.
Yingying Weng   +7 more
openaire   +2 more sources

[Characterization of microRNAs profiles of induced pluripotent stem cells reprogrammed from human dental pulp stem cells and stem cells from apical papilla].

Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology, 2017
To compare characterization of microRNAs (miRNAs) expression profiles of induced pluripotent stem cells (iPSCs) reprogrammed from human dental pulp stem cells (DPSCs) and stem cells from apical papilla (SCAP) and screen-specific microRNA.Human DPSCs and SCAP were reprogrammed into iPSCs using a Sendai virus vector.
Tan, Xiaobing, Dai, Qingyuan
openaire   +1 more source

[Effect of baicalin on osteogenic differentiation of stem cells from human apical papilla].

Shanghai kou qiang yi xue = Shanghai journal of stomatology, 2019
To investigate the effect of baicalin on osteogenic differentiation of stem cells from human apical papilla(SCAPs).The third-passage SCAPs with stable passage ability were selected. After culturing for 24 hours in a medium containing 0, 10, 20, 50, 100 μmol/L of baicalin, cell viability in each group was measured by live/dead fluorescence staining ...
Yong-Gang, Ma   +3 more
openaire   +1 more source

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