Results 191 to 200 of about 8,372 (230)

Stem cells from apical papilla promote differentiation of human pluripotent stem cells towards retinal cells

Differentiation, 2018
Recently, we have found that human stem cells from apical papilla (SCAP) show a stromal cell-derived inducing activity (SDIA). To examine SDIA competence for retinal cells differentiation, we co-cultured SCAP with human pluripotent stem cells (hPSCs).
Fereshteh, Karamali, Mohammad-Hossein Nasr, Esfahani, Sara, Taleahmad, Leila, Satarian, Hossein, Baharvand   +4 more
openaire   +4 more sources

Role of CPNE1 in Odontoblastic Differentiation of Rat Stem Cells from Apical Papilla

Advanced Biology, 2023
AbstractCPNE1 is a calcium‐dependent, phospholipid‐binding protein that is ubiquitously expressed in various tissues and organs. This study investigates the expression and localization of CPNE1 in tooth germ development and the role of CPNE1 in odontoblastic differentiation.
Xi Lu, Han Xie, Yanqin Ju, Yunyu Fu, Shangfeng Liu, Shouliang Zhao   +5 more
openaire   +2 more sources

Engineering a Novel Stem Cells from Apical Papilla-Macrophages Organoid for Regenerative Endodontics

Journal of Endodontics, 2022
A 3-dimensional (3D) tissue construct with a heterogeneous cell population is critical to understand the interactions between immune cells and stem cells from the apical papilla (SCAPs) in the periapical region for developing treatment strategies in regenerative endodontics.
Fang-Chi Li, Alireza Shahin-Shamsabadi, P. Ravi Selvaganapathy, Anil Kishen   +3 more
openaire   +2 more sources

Overexpression of ephrinB2 in stem cells from apical papilla accelerates angiogenesis

Oral Diseases, 2019
AbstractObjectivesWe aimed to accelerate angiogenesis in pulp regeneration by modulating ephrinB2 expression in stem cells from apical papilla (SCAPs).Materials and MethodsStem cells from apical papilla were transducted with ephrinB2‐lentiviral expression vector (ephrinB2‐SCAPs) in experimental group and green fluorescent protein (GFP‐SCAPs) in control
Changyong Yuan, Penglai Wang, Shaoyue Zhu, Zongxiang Liu, Wen Wang, Tengyu Geng, Waruna Lakmal Dissanayaka, Lijian Jin, Chengfei Zhang   +8 more
openaire   +2 more sources

Profiling the Secretome of Human Stem Cells from Dental Apical Papilla

Stem Cells and Development, 2016
Recent studies have shown that secretion of bioactive factors from mesenchymal stem cells (MSCs) plays a primary role in MSC-mediated therapy; especially for bone marrow-derived MSCs (BMSCs). MSCs from dental apical papilla (SCAPs) are involved in root development and may play a critical role in the formation of dentin and pulp.
Shi, Yu, Yuming, Zhao, Yushi, Ma, Lihong, Ge   +3 more
openaire   +2 more sources

Substrate Mechanics Dictates Cell-Cell Communication via Gap Junction in Stem Cells from Human Apical Papilla

SSRN Electronic Journal, 2019
It is recognized that the interaction between cells and their physical microenvironment plays a fundamental role in controlling cell behaviors and even in determining cell fate. Any change in the physical properties of the extracellular matrix (ECM), such as its topography, geometry, and stiffness, controls this interaction.
Chenchen Zhou, Demao Zhang, Wei Du, Jing Zou, Xiaobing Li, Jing Xie   +5 more
openaire   +2 more sources

Interactions of Neuronally Induced Stem Cells from Apical Papilla Spheres, Stems Cells from Apical Papilla, and Human Umbilical Vascular Endothelial Cells on Vasculogenesis and Neurogenesis

Journal of Endodontics
Stem cell-based dental pulp regeneration has been extensively studied, mainly focusing on exploiting dental stem cells' osteogenic and angiogenic potentials. Dental stem cells' neurogenic role is often overlooked. Stem cells from apical papilla (SCAPs), originating from the neural crest and capable of sphere formation, display potent neurogenic ...
Mohammed S. Basabrain, Jialin Zhong, Junqing Liu, Yuchen Zhang, Mohamed Mahmoud Abdalla, Chengfei Zhang   +5 more
openaire   +2 more sources

SFRP2 promotes stem cells from apical papilla‐mediated periodontal tissue regeneration in miniature pig

Journal of Oral Rehabilitation, 2019
AbstractMesenchymal stem cell‐based therapy is a reliable treatment for periodontal tissue regeneration, while ideal regeneration rate is still a facing problem. In previous study, we found SFRP2 a promising gene in modulating mesenchymal stem cells potential. We further investigated its role on periodontal tissue regeneration. We created periodontitis
Guoqing Li, Nannan Han, Haoqing Yang, Xiuli Zhang, Yangyang Cao, Yu Cao, Ruitang Shi, Songlin Wang, Zhipeng Fan   +8 more
openaire   +2 more sources

PDGFBB-modified stem cells from apical papilla and thermosensitive hydrogel scaffolds induced bone regeneration

Chemico-Biological Interactions, 2020
Bone defects caused by cancer surgery or trauma have a strong negative impact on human health. Treatment with cell and material-based complexes provides an alternative strategy for the regeneration of damaged bone tissue. The good physical properties and suitable biodegradability of a thermosensitive hydrogel has been shown to act as a valuable ...
Jiajia, Deng, Jie, Pan, Xinxin, Han, Liming, Yu, Jing, Chen, Weihua, Zhang, Luying, Zhu, Wei, Huang, Shangfeng, Liu, Zhengwei, You, Yuehua, Liu   +10 more
openaire   +2 more sources

Effect of cryopreservation on biological and immunological properties of stem cells from apical papilla

Journal of Cellular Physiology, 2010
AbstractStem cells from apical papilla (SCAP) are a novel population of multipotent stem cells that, although similar to dental pulp stem cells, are a discrete source of dental stem cells. SCAP have potential roles in root development, apexogenesis, pulp/dentin regeneration, and bioroot engineering.
Gang, Ding, Wei, Wang, Yi, Liu, Yunqing, An, Chunmei, Zhang, Songtao, Shi, Songlin, Wang   +6 more
openaire   +2 more sources