Viability and Stimulation of Human Stem Cells from the Apical Papilla (hSCAPs) Induced by Silicate-Based Materials for Their Potential Use in Regenerative Endodontics: A Systematic Review. [PDF]
Materials (Basel), 2020 Sanz JL +4 more
europepmc +2 more sources
Conversion of stem cells from apical papilla into endothelial cells by small molecules and growth factors [PDF]
Stem Cell Research & Therapy, 2021 Abstract Objectives Recently, a new strategy has been developed to directly reprogram one cell type towards another targeted cell type using small molecule compounds. Human fibroblasts have been chemically reprogrammed into neuronal cells, Schwann cells and cardiomyocyte-like cells by different small molecule ...
Baicheng Yi +8 more
openaire +3 more sources
Mesenchymal stem cell-mediated functional tooth regeneration in swine. [PDF]
PLoS ONE, 2006 Mesenchymal stem cell-mediated tissue regeneration is a promising approach for regenerative medicine for a wide range of applications. Here we report a new population of stem cells isolated from the root apical papilla of human teeth (SCAP, stem cells ...
Wataru Sonoyama +10 more
doaj +1 more source
Effects of iRoot SP on osteogenic differentiation of human stem cells from apical papilla [PDF]
BMC Oral Health, 2021 Abstract Background Research shows that nano-bioceramics can modulate the differentiation of dental stem cells. The novel ready-to-use calcium-silicate-based root-canal sealer iRoot SP is widely used in root filling.
Laidi Wu +6 more
openaire +3 more sources
Effect of Long-Term Cryopreservation on the Stemness of Stem Cells of Apical Papilla
International Journal of Dentistry, 2022 Stem cells of apical papilla (SCAPs) are considered a subpopulation of dental stem cells with unique properties. They originate from a developing tissue, the apical papilla of developing teeth, a characteristic that enhances their stemness.
Anna Digka +3 more
doaj +1 more source
Journal of Tissue Engineering, 2022 Apical periodontitis (AP) causes arrest of tooth root development, which is associated with impaired odontoblastic differentiation of stem cells from apical papilla (SCAPs), but the underlying mechanism remains unclear.
Shengyan Yang +8 more
doaj +1 more source
Evaluation of the Cytotoxicity of Two Types of Triple Antibiotic Paste on Human Permanent Dental Apical Papilla Stem Cells: an in vitro Study [PDF]
Journal of Dentistry, 2022 Statement of the Problem: The use of a new antimicrobial combination in the regenerative endodontic treatment of immature teeth pulp necrosis is a well-known method.
Rezvan Rafatjou +4 more
doaj +1 more source
Effect of Biodentine Coated with Emdogain on Proliferation and Differentiation of Stem Cells from the Apical Papilla [PDF]
Molecular Biology Reports, 2021 Abstract Background: This study assessed the effect of Biodentine coated with Emdogain (Biodentine/Emdogain) on proliferation and differentiation of stem cells from the apical papilla (SCAP). Methods and Results: In this in vitro, experimental study, SCAP were isolated from two immature impacted third molars and cultured.
Hamed Karkehabadi +3 more
openaire +2 more sources
Biomaterials and Scaffold Design Strategies for Regenerative Endodontic Therapy
Frontiers in Bioengineering and Biotechnology, 2019 Challenges with traditional endodontic treatment for immature permanent teeth exhibiting pulp necrosis have prompted interest in tissue engineering approaches to regenerate the pulp-dentin complex and allow root development to continue.
Gavin Raddall +3 more
doaj +1 more source
Basic Fibroblast Growth Factor Enhances Stemness of Human Stem Cells from the Apical Papilla [PDF]
Journal of Endodontics, 2012 Stem cells from the apical papilla (SCAP) are a type of mesenchymal stem cells found in the developing tissue, apical papilla, of immature permanent teeth. Studies have shown that SCAP are likely to be a source of primary odontoblasts that are responsible for the formation of root dentin.
Jiayuan, Wu +8 more
openaire +2 more sources