Results 21 to 30 of about 4,230 (175)

Neural Regenerative Potential of Stem Cells Derived from the Tooth Apical Papilla [PDF]

Stem Cells and Development, 2020
The regenerative effects of stem cells derived from dental tissues have been previously investigated. This study assessed the potential of human tooth stem cells from apical papilla (SCAP) on nerve regeneration. The SCAP collected from nine individuals were characterized and polarized by exposure to interferon-γ (IFN-γ).
Ana Paula Aquistapase, Dagnino, Pedro Cesar, Chagastelles, Renata Priscila, Medeiros, Marina, Estrázulas, Luiza Wilges, Kist, Maurício Reis, Bogo, João Batista Blessmann, Weber, Maria Martha, Campos, Jefferson Braga, Silva   +8 more
openaire   +2 more sources

Mesenchymal stem cell-mediated functional tooth regeneration in swine. [PDF]

PLoS ONE, 2006
Mesenchymal stem cell-mediated tissue regeneration is a promising approach for regenerative medicine for a wide range of applications. Here we report a new population of stem cells isolated from the root apical papilla of human teeth (SCAP, stem cells ...
Wataru Sonoyama, Yi Liu, Dianji Fang, Takayoshi Yamaza, Byoung-Moo Seo, Chunmei Zhang, He Liu, Stan Gronthos, Cun-Yu Wang, Songlin Wang, Songtao Shi   +10 more
doaj   +1 more source

Conversion of stem cells from apical papilla into endothelial cells by small molecules and growth factors [PDF]

Stem Cell Research & Therapy, 2021
Abstract Objectives Recently, a new strategy has been developed to directly reprogram one cell type towards another targeted cell type using small molecule compounds. Human fibroblasts have been chemically reprogrammed into neuronal cells, Schwann cells and cardiomyocyte-like cells by different small molecule ...
Baicheng Yi, Tian Ding, Shan Jiang, Ting Gong, Hitesh Chopra, Ou Sha, Waruna Lakmal Dissanayaka, Shaohua Ge, Chengfei Zhang   +8 more
openaire   +3 more sources

Effect of Long-Term Cryopreservation on the Stemness of Stem Cells of Apical Papilla

International Journal of Dentistry, 2022
Stem cells of apical papilla (SCAPs) are considered a subpopulation of dental stem cells with unique properties. They originate from a developing tissue, the apical papilla of developing teeth, a characteristic that enhances their stemness.
Anna Digka, Eleni Gounari, Kokkona Kouzi-Koliakou, Kleoniki Lyroudia   +3 more
doaj   +1 more source

Extracellular vesicles delivering nuclear factor I/C for hard tissue engineering: Treatment of apical periodontitis and dentin regeneration

Journal of Tissue Engineering, 2022
Apical periodontitis (AP) causes arrest of tooth root development, which is associated with impaired odontoblastic differentiation of stem cells from apical papilla (SCAPs), but the underlying mechanism remains unclear.
Shengyan Yang, Qing Liu, Shijing Chen, Fuping Zhang, Yaoyin Li, Wenguo Fan, Lijia Mai, Hongwen He, Fang Huang   +8 more
doaj   +1 more source

Evaluation of the Cytotoxicity of Two Types of Triple Antibiotic Paste on Human Permanent Dental Apical Papilla Stem Cells: an in vitro Study [PDF]

Journal of Dentistry, 2022
Statement of the Problem: The use of a new antimicrobial combination in the regenerative endodontic treatment of immature teeth pulp necrosis is a well-known method.
Rezvan Rafatjou , Arghavan Kamali Sabeti , Bahar Ahmadi , Sara Soleimani Asl , Maryam Farhadian   +4 more
doaj   +1 more source

Effects of iRoot SP on osteogenic differentiation of human stem cells from apical papilla [PDF]

BMC Oral Health, 2021
Abstract Background Research shows that nano-bioceramics can modulate the differentiation of dental stem cells. The novel ready-to-use calcium-silicate-based root-canal sealer iRoot SP is widely used in root filling.
Laidi Wu, Kaiyang Xue, Guang Hu, Hanman Du, Kang Gan, Juanfang Zhu, Tianfeng Du   +6 more
openaire   +3 more sources

Effect of Biodentine Coated with Emdogain on Proliferation and Differentiation of Stem Cells from the Apical Papilla [PDF]

Molecular Biology Reports, 2021
Abstract Background: This study assessed the effect of Biodentine coated with Emdogain (Biodentine/Emdogain) on proliferation and differentiation of stem cells from the apical papilla (SCAP). Methods and Results: In this in vitro, experimental study, SCAP were isolated from two immature impacted third molars and cultured.
Hamed Karkehabadi, Erfan Ahmadyani, Rezvan Najafi, Elham Khoshbin   +3 more
openaire   +2 more sources

Biomaterials and Scaffold Design Strategies for Regenerative Endodontic Therapy

Frontiers in Bioengineering and Biotechnology, 2019
Challenges with traditional endodontic treatment for immature permanent teeth exhibiting pulp necrosis have prompted interest in tissue engineering approaches to regenerate the pulp-dentin complex and allow root development to continue.
Gavin Raddall, Isabel Mello, Brendan M. Leung, Brendan M. Leung   +3 more
doaj   +1 more source

Mechanical plaque removal in step‐1 of care

Periodontology 2000, EarlyView., 2023
Abstract Maintaining a regular oral hygiene routine is essential for taking care of our mouths, ensuring healthy teeth, and achieving fresh breath. Patient education on oral hygiene is an important component of their overall treatment. Firstly, patients should be informed about the direct connection between bacteria in dental plaque and oral diseases ...
G. A. (Fridus) Van der Weijden, Cor van Loveren   +1 more
wiley   +1 more source