Results 51 to 60 of about 4,230 (175)

NOTCH3 is expressed in human apical papilla and in subpopulations of stem cells isolated from the tissue

Genes & Diseases, 2015
NOTCH plays a role in regulating stem cell function and fate decision. It is involved in tooth development and injury repair. Information regarding NOTCH expression in human dental root apical papilla (AP) and its residing stem cells (SCAP) is limited.
Jamal, Mohamed, Chogle, Sami M., Karam, Sherif M., Huang, George T.-J.   +3 more
openaire   +2 more sources

Effect of bFGF on the growth and matrix turnover of stem cells from human apical papilla: Role of MEK/ERK signaling

Journal of the Formosan Medical Association, 2020
Background/Purpose: Basic fibroblast growth factor (bFGF) exhibits multiple biological functions in various tissues. Stem cells from apical papilla (SCAP) can be isolated from human apical papilla tissues in developmental teeth of children.
Mei-Chi Chang, Chih-Yu Chen, Ya-Ching Chang, Bo-Hao Zhong, Yin-Lin Wang, Sin-Yuet Yeung, Hsiao-Hua Chang, Jiiang-Huei Jeng   +7 more
doaj   +1 more source

LGR6 couples maresin 1 signaling to glycolytic flux and protein lactylation for the rescue of diabetic cardiomyopathy

Journal of Diabetes Investigation, EarlyView.
MaR1 activates LGR6‐AMPK signaling to restore metabolic flexibility in diabetic hearts. Glycolytic recovery replenishes intracellular lactate to rescue protective protein lysine lactylation, which reactivates PINK1/Parkin‐mediated mitophagy to eliminate damaged mitochondria.
Bin Feng, Chao Chen, Lin Chen, Yuqiong Chen, Wenjun Mao, Peiran Yu, Hao Yu, Bimin Shi, Nannan Zhang   +8 more
wiley   +1 more source

Dental Tissue — New Source for Stem Cells

The Scientific World Journal, 2009
Stem cells have been isolated from many tissues and organs, including dental tissue. Five types of dental stem cells have been established: dental pulp stem cells, stem cells from exfoliated deciduous teeth, stem cells from apical papilla, periodontal ...
Vladimir Petrovic, Vladisav Stefanovic
doaj   +1 more source

The Effect of Liquid-Phase Exfoliated Graphene Film on Neurodifferentiation of Stem Cells from Apical Papilla

Nanomaterials, 2022
Background: Dental stem cells, which originate from the neural crest, due to their easy accessibility might be good candidates in neuro-regenerative procedures, along with graphene-based nanomaterials shown to promote neurogenesis in vitro.
Jelena Simonovic, Bosko Toljic, Milos Lazarevic, Maja Milosevic Markovic, Mina Peric, Jasna Vujin, Radmila Panajotovic, Jelena Milasin   +7 more
doaj   +1 more source

Comprehensive revision of Mallomonas sect. Peroneides stat. nov. (Chrysophyceae) integrating morphology and multigene phylogeny

Journal of Phycology, EarlyView.
Abstract Mallomonas is among the most diverse genera of Chrysophyceae, yet many of its lineages remain taxonomically unresolved due to limited molecular sampling. Mallomonas series Peronoides, historically limited to four species, has posed persistent taxonomic difficulties, most notably the long‐standing and problematic reliance on a rare ...
Petr Knotek, Iva Jadrná, Martin Pusztai, Pavel Škaloud   +3 more
wiley   +1 more source

Dental regenerative therapy targeting sphingosine-1-phosphate (S1P) signaling pathway in endodontics

Japanese Dental Science Review, 2020
The establishment of regenerative therapy in endodontics targeting the dentin-pulp complex, cementum, periodontal ligament tissue, and alveolar bone will provide valuable information to preserve teeth.
Etsuko Matsuzaki, Masahiko Minakami, Noriyoshi Matsumoto, Hisashi Anan   +3 more
doaj   +1 more source

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

Journal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag, Magdalena Mayol, Danijel Domic, Madhusudhan Reddy Bobbili, Johannes Grillari, Mariano Sanz, Reinhard Gruber   +6 more
wiley   +1 more source

Cell Therapy for Periodontal, Soft‐Tissue, and Craniofacial Regeneration

Journal of Periodontal Research, EarlyView.
The clinical translation of mesenchymal stem/stromal cells (MSCs) represents a major advancement in dentistry, especially for periodontal, soft‐tissue, and craniofacial regeneration. However, several challenges remain to be addressed, including the absence of standardised protocols, limited scalability, regulatory hurdles, a lack of well‐controlled ...
Kamal Mustafa, Shuntaro Yamada, Nerea Sanchez, Magdalena Mayol, Cecilie Gjerde, Mariano Sanz   +5 more
wiley   +1 more source

Betaine enhances SCAPs chondrogenic differentiation and promotes cartilage repair in TMJOA through WDR81

Stem Cell Research & Therapy
Background The cartilage tissue regeneration mediated with mesenchymal stem cells (MSCs) is considered as a viable strategy for temporomandibular joint osteoarthritis (TMJOA). Betaine has been confirmed to modulate the multidirectional differentiation of
Meiyue Wang, Zejie Wu, Xiaoyu Zheng, Yishu Huang, Yizhou Jin, Jiaxin Song, Wanzhen Lei, Hua Liu, Riyue Yu, Haoqing Yang, Runtao Gao   +10 more
doaj   +1 more source