Results 101 to 110 of about 38,975 (250)

Modulation of bone morphogenetic protein activity by melatonin in ovarian steroidogenesis

Reproductive Medicine and Biology, 2018
Background Melatonin regulates circadian and seasonal rhythms and the activities of hormones and cytokines that are expressed in various tissues, including the ovary, in which melatonin receptors are expressed. In the ovary, follicular growth occurs as a
Fumio Otsuka
doaj   +1 more source

Ro5‐4864, a ligand of the mitochondrial translocator protein, protects against heart failure in mice via regulation of the p62‐Keap1‐Nrf2 axis

The Journal of Physiology, EarlyView.
Abstract figure legend Graphical abstract of the proposed Ro5‐4864 mechanism of action via p62‐Keap1‐Nrf2 axis in heart failure. TSPO, the 18‐kDa mitochondrial translocator protein of the outer mitochondrial membrane, can directly interact with p62 (also known as SQSTM1), which is crucial for the degradation of damaged mitochondria by autophagy ...
Daphne A. Diloretto, Phung N. Thai, Gabriela Grigorean, Veneese J. Brown, Tjien Dwyer, Nipavan Chiamvimonvat, Elena N. Dedkova, Saul Schaefer   +7 more
wiley   +1 more source

Physiological and anatomical determinants of placental drug transfer

The Journal of Physiology, EarlyView.
Abstract figure legend Fetal exposure to pharmaceuticals and their subsequent clearance back to the maternal circulation are governed by placental transfer. Passive diffusion down a maternal‐to‐fetal concentration gradient is the primary route of fetal drug exposure, with specific compounds undergoing transporter‐mediated transfer.
Rohan M. Lewis, Anandita Umapathy, Jane K. Cleal, Bram G. Sengers   +3 more
wiley   +1 more source

Development and Clinical Significance of the Human Fetal Adrenal Gland as a Key Component of the Feto-Placental System: A Systematic Review

Reproductive Medicine
Background: The human fetal adrenal gland is a unique endocrine organ with distinct morphology and functional dynamics, which is significantly different from the postnatal adrenal.
Martiniuc Ana-Elena, Laurentiu-Camil Bohiltea, Pop Lucian Gheorghe, Suciu Nicolae   +3 more
doaj   +1 more source

Effect of xenobiotic compounds on steroidogenesis in humans

, 2023
Gonadal steroids are crucial hormones responsible for the proper functioning and growth of the body. The sex hormones are produced in the adrenal glands and gonads by a process called steroidogenesis.
Preeti Karki, Rekha Mirle, V. Swarupa, Raksha P, K.M. Abdullah, Pragathi Reddy, Niveditha Nittoor   +6 more
core  

Global Fluoride Toxicology Landscape: Bibliometric Approaches and Scientific Mapping

Environmental Toxicology, Volume 41, Issue 7, Page 416-458, July 2026.
ABSTRACT This study analyzed research trends in the 100 most‐cited articles on fluoride toxicology, a topic widely debated due to the toxic effects associated with levels deemed safe for human exposure. A bibliometric analysis was conducted using the Web of Science‐Core Collection, extracting data such as citation count, authors, keywords, journal ...
Maria Karolina Martins Ferreira, Deiweson Souza‐Monteiro, Priscila Cunha Nascimento, Luciana Eiró‐Quirino, Leonardo Oliveira Bittencourt, Fatemeh Vida Zohoori, Esperanza Angeles Martinez‐Mier, Marilia Afonso Rabelo Buzalaf, Rafael Rodrigues Lima   +8 more
wiley   +1 more source

Microgravity impairs endocrine signaling and reproductive health of women. A narrative review

Frontiers in Physiology
During space exploration missions the organism is subjected to several challenges. Most of the studies have been performed on male health in space, leaving the focus on sex differences behind.
Michela Cutigni, Giorgia Cucina, Emanuele Galante, Matteo Cerri, Mariano Bizzarri   +4 more
doaj   +1 more source

Polymorphism of the Gonadotropin‐Releasing Hormone Receptor Gene and Its Association With Production Traits in Isfahani Native Hens

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
This research was conducted to identify genetic polymorphisms of the GNRHR gene on Isfahan native hen traits and their relationship with production traits. For this purpose, blood was taken, DNA was extracted, the target fragment was amplified and directly sequenced, and finally it was blasted with the reference gene in NCBI.
Farshid Kheiri, Mostafa Faghani, Mohammad Mohammadi Berenjegani, Somayeh Tirbakhsh Gouran, Matin Rahimi Domakani   +4 more
wiley   +1 more source

Dihydrotanshinone as a Natural Product-Based CYP17A1 Lyase Inhibitor for Hyperandrogenic Disorders

Biomolecules
Selective inhibition of CYP17A1 17,20-lyase is critical for treating hyperandrogenic disorders without the cortisol-depleting side effects of non-selective drugs like abiraterone.
Kaige Li, Jibira Yakubu, Flemming Steen Jørgensen, Amit V. Pandey   +3 more
doaj   +1 more source

Comparative Effects of Laparotomy and Laparoscopy‐Assisted Embryo Transfer on Oxidative Stress and Thiol–Disulphide Homeostasis in Tuj Ewes

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
Laparoscopic embryo transfer in Tuj ewes induces less oxidative stress and better preserves thiol–disulphide homeostasis than laparotomy. These findings indicate that minimally invasive approaches better maintain redox balance and antioxidant defence during embryo transfer procedures.
Murat Can Demir, Merve Sena Demir, Mustafa Makav, Semra Kaya, Taygun Gökdemir, Nail Tekin Önder, Mushap Kuru, Cihan Kaçar   +7 more
wiley   +1 more source