Results 141 to 150 of about 117,522 (314)

Prevention of Myc‐Driven Prostate Cancer in Mice by Oral Administration of Sulforaphane

open access: yesMolecular Carcinogenesis, EarlyView.
ABSTRACT Prevention is desirable to reduce suffering and death from prostate cancer. However, a clinical‐grade intervention for the prevention of this malignancy is still lacking. This study was undertaken to determine the feasibility of prostate cancer prevention by broccoli constituent sulforaphane (SFN) because epidemiological studies have suggested
Krishna B. Singh   +3 more
wiley   +1 more source

Differentiation of Plant and Animal‐Derived Cholesterol Using irm‐13C NMR and IRMS

open access: yesMagnetic Resonance in Chemistry, EarlyView.
Determining and certifying the origin of ingredients, starting materials, and excipients used in manufactured goods like cosmetics and medicines can be difficult. In this report, we describe a robust approach for identifying the origin of cholesterol, a component of myriad consumer products using irm‐13C NMR and IRMS to differentiate plant versus ...
Anika M. Singh   +3 more
wiley   +1 more source

Lipodystrophy and adipose tissue recovery are mediated by the Wnt/lipogenesis axis during skin fibrosis

open access: yesThe Journal of Pathology, EarlyView.
Abstract Acquired lipodystrophy in the dermal white adipose tissue (DWAT) is an early phenotype of skin fibrosis, followed by the accumulation of extracellular matrix (ECM). Lipodystrophy syndromes are estimated to affect 1 in 20,000 people and are associated with metabolic comorbidities.
Suneeti R Madhavan   +10 more
wiley   +1 more source

Sterol assimilation by Saccharomyces cerevisiae

open access: yes
Sterols of the yeast Saccharomyces cerevisiae are found in membranes with a free C-3,β hydroxyl group or stored in lipid droplets as esters of long-chain fatty acids.
Lewis, Thomas A.
core  

Branched‐Chain Amino and Keto Acids Reduce Hepatocyte Lipid Droplet Size and Number via Distinct Proteomic Pathways

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Branched‐chain amino acids (BCAA) and their corresponding keto acids (BCKA) have been associated with changes in hepatic lipid metabolism and the resulting alterations in intracellular triglyceride concentrations. In this study, we utilized a previously established hepatocyte model to investigate the impact of BCAA and BCKA supplementation on ...
Jayasimha R. Daddam   +4 more
wiley   +1 more source

Effects of Cultivar and Row Spacing on Tocopherol and Sterol Composition of Chickpea Cicer arietinum L Seed Oil

open access: yesJournal of Agricultural Sciences, 2009
Effect of cultivars and row spacing RS on tocopherol and sterol composition of chickpea oil from chickpea, grown under semi-arid conditions of Thal, Pakistan has been studied.
Muhammad Zia-ul-haq   +4 more
doaj  

Comprehensive DIA‐MS Proteomics of Root Basal Nodes Elucidates Mechanisms of Salt Tolerance in Rice

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Soil salinity severely affects rice growth, yield, and quality, posing a global food security challenge. Rice is particularly vulnerable to high salinity, which restricts growth and tolerance to other stresses. To address this, breeding efforts have been made in the past, leading to the generation of multi‐stress‐tolerant rice lines.
Cheol Woo Min   +8 more
wiley   +1 more source

Alcoholic extracts of Russian sage (Salvia yangii) contain bioactive terpenoids with inhibitory activity against grapevine downy mildew (Plasmopara viticola)

open access: yesPest Management Science, EarlyView.
Alcoholic extracts from flowers, leaves, and shoots of Russian sage decreased downy mildew severity on grapevine leaf disks. Fractionation followed by metabolomic analysis revealed putative terpenoids as the main components of the active fractions. Specifically, 7‐methylrosmanol, 12‐O‐methylcarnosic acid, carnosic acid, and carnosol were identified as ...
Anna Smaldone   +5 more
wiley   +1 more source

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