From small to big molecules: how do we prevent and delay the progression of age-related neurodegeneration? [PDF]
, 2012 Age-related neurodegeneration in the brain and retina is complicated. It comprises a series of events encompassing different modes of degeneration in neurons, as well as inflammation mediated by glial cells.
Chan, TF, Chang, RCC, Ho, YS, Poon, CHD
core +1 more source
Stilbenes: biomarkers of grapevine resistance to fungal diseases
OENO One, 2018 Since the introduction of powdery and downy mildews in Europe in the late 19th century, breeding resistant cultivars by hybridizing V. vinifera (susceptible) with other Vitis species (resistant) has been largely used and led, in 1947, to the cultivation ...
Viret Olivier +2 more
doaj +1 more source
Evaluation of Anti-cancer Activity of Stilbene and Methoxydibenzo[b,f] oxepin Derivatives [PDF]
, 2017 Background: Stilbenes, 1,2-diphenylethen derivatives, including resveratrol and combretastatins, show anticancer features especially against tumor angiogenesis. Fosbretabulin, CA-4, in combination with carboplatin, is in the last stages of clinical tests
Dębski, Janusz +10 more
core
Characterization, antibacterial and biological activities of phenolic fraction of argentinean red wines [PDF]
, 2014 For the first time, the qualitative and quantitative characterization of phenolic compounds of lower molecular weight fraction (LMF) were evaluated in commercial Cabernet Sauvignon (CS) and Tannat (T) wines varieties produced in Cafayate, Argentine.
Aredes Fernández, Pedro Adrián +5 more
core +1 more source
Electron Transfer Prompted Ejection of a Tightly Bound K\u3csup\u3e+\u3c/sup\u3e from the Ethereal Cavity of a Hexaarylbenzene-Based Receptor [PDF]
, 2007 Synthesis of a pair of rotamers (9u/9s) of a hexaarylbenzene derivative containing six (cofacially arranged) electroactive 2,5-dimethoxytolyl groups is described.
Lindeman, Sergey V. +2 more
core +1 more source
The vicinal difluoro motif : the synthesis and conformation of erythro- and threo-diastereoisomers of 1,2-difluorodiphenylethanes, 2,3-difluorosuccinic acids and their derivatives [PDF]
, 2013 Background: It is well established that vicinal fluorines (RCHF-CHFR) prefer to adopt a gauche rather than an anti conformation when placed along aliphatic chains.
O'Hagan, David +3 more
core +1 more source
Synthesis of derivatives of methoxydibenzo[b, f]oxepine in the presence of sodium azide [PDF]
, 2016 Dibenzo[b,f]oxepine is an important scaffold in medicinal chemistry and its derivatives occur in several medicinally important plants. A new approach to methoxydibenzo[b,f]oxepines (15–21) proceeding under mild reaction conditions, has been developed ...
Grzesiuk, Elzbieta +4 more
core +1 more source
Rugulopteryx okamurae extract provides protection against Plasmopara viticola
OENO OneThere is currently a need to assess new, sustainable strategies for downy mildew control on grapevines in accordance with the Goals of the 2030 Agenda for Sustainable Development.
Emma Cantos-Villar +10 more
doaj +1 more source
Recent Advances in the Recombinant Biosynthesis of Polyphenols
Frontiers in Microbiology, 2017 Plants are the source of various natural compounds with pharmaceutical and nutraceutical importance which have shown numerous health benefits with relatively fewer side effects. However, extraction of these compounds from native producers cannot meet the
Sonam Chouhan +5 more
doaj +1 more source
Polyphenol intake and mortality risk: a re-analysis of the PREDIMED trial [PDF]
, 2014 Background: Polyphenols may lower the risk of cardiovascular disease (CVD) and other chronic diseases due to their antioxidant and anti-inflammatory properties, as well as their beneficial effects on blood pressure, lipids and insulin resistance. However,
Aros, Fernando +20 more
core +1 more source