Results 61 to 70 of about 17,560 (256)

Targeting Hippocampal PTEN Suppresses Ferroptosis and Rescues Cognitive Decline in Alzheimer's Disease via Dual AKT/GSK3β/Nrf2 and AKT/STAT3 Axes

Advanced Science, EarlyView.
PTEN knockdown activates AKT phosphorylation, promoting Nrf2 nuclear translocation and STAT3 activation, which upregulates GPX4 and antioxidant enzymes HO‐1, SOD1, SOD2, and NQO1. These coordinated changes reduce lipid peroxidation and ROS, inhibit ferroptosis, and ultimately ameliorate cognitive impairment in APP/PS1 transgenic mice, highlighting a ...
Da‐Wei Wang, Meng‐Meng Liu, Yu‐Chen Zhao, Jia‐Yi Li, Wen Li, Xin Yu   +5 more
wiley   +1 more source

Effect of piceatannol-rich passion fruit seed extract on human glyoxalase I–mediated cancer cell growth

Biochemistry and Biophysics Reports, 2019
Passion fruit seed extract (PFSE), a product rich in stilbenes such as piceatannol and scirpusin B, has various physiological effects. It is unclear whether PFSE and its stilbene derivatives inhibit cancer cell proliferation via human glyoxalase I (GLO I)
Takayuki Yamamoto, Akira Sato, Yusuke Takai, Atsushi Yoshimori, Masahiro Umehara, Yoko Ogino, Mana Inada, Nami Shimada, Aya Nishida, Risa Ichida, Ryoko Takasawa, Hiroko Maruki-Uchida, Sadao Mori, Masahiko Sai, Minoru Morita, Sei-ichi Tanuma   +15 more
doaj   +1 more source

Rapid Photogelation of Low‐Concentration Polymer Solutions via Photodimerization of o‐Ethylnitrobenzene

Advanced Science, EarlyView.
Upon UV irradiation, flexible and tough hydrogels are formed rapidly (>0.5 s) from dilute (>0.5 wt%) solutions of o‐ethylnitrobenzene–modified PVA. At ∼1.5 wt%, the hydrogels withstand up to 10 MPa compression, remain handleable even after 200‐fold swelling.
Masaaki Okihara, Ayaka Tomoda, Kana Morishita, Toshiyuki Takagi, Kimio Sumaru   +4 more
wiley   +1 more source

The Interplay Between Autophagy and Apoptosis in the Mechanisms of Action of Stilbenes in Cancer Cells

Antioxidants
Plant-based stilbenes are low-molecular-weight polyphenolic compounds that exhibit anti-oxidant, anti-microbial, anti-fungal, anti-inflammatory, anti-diabetic, cardioprotective, neuroprotective, and anti-cancer activities.
Kamila Siedlecka-Kroplewska, Zbigniew Kmiec, Michal Aleksander Zmijewski   +2 more
doaj   +1 more source

Ueber Tetraamido‐stilben [PDF]

Berichte der deutschen chemischen Gesellschaft, 1904
n ...
openaire   +1 more source

Trans-Stilbenes in Commercial Grape Juices: Quantification Using HPLC Approaches [PDF]

, 2016
Trans-stilbenes belong to the group of polyphenolic phytoalexins, and occur in many plant foods. These compounds have received great attention by researchers due to their well-known beneficial health effects. In the present study a chromatographic method
Julia López-Hernández, Ana Rodríguez-Bernaldo de Quirós, López Hernández, María Julia Celia, Rodríguez Bernaldo de Quirós, Ana Isabel   +3 more
core   +1 more source

Chemical Profiling on Bioactive Stilbenoids in the Seeds of Paeonia Species Growing Wild in Greece

Separations, 2023
The seeds of Paeonia clusii Stern subsp. clusii and Paeonia mascula (L.) Mill. subsp. mascula growing wild in Greece, though not previously investigated, has been studied as a source of bioactive stilbenoids and other phenolics.
Eleni Dimitropoulou, Konstantia Graikou, Vithleem Klontza, Ioanna Chinou   +3 more
doaj   +1 more source

An Overview on Plant Derived Phenolic Compounds and Their Role in Treatment and Management of Diabetes

Journal of Pharmacopuncture, 2022
Objectives: In recent decades, the trend for treating diabetes mellitus (DM) has shifted toward alternative medicines that are obtained from plant sources.
Himangshu Deka, Ananta Choudhury, Biplab Kumar Dey   +2 more
doaj   +1 more source

Synthesis and Biological Evaluation of Halogenated E-Stilbenols as Promising Antiaging Agents

Molecules, 2020
The increased risk of illness and disability is related to the age inevitable biological changes. Oxidative stress is a proposed mechanism for many age-related diseases.
Ester Sara Di Filippo, Letizia Giampietro, Barbara De Filippis, Marwa Balaha, Vincenzo Ferrone, Marcello Locatelli, Tiziana Pietrangelo, Angela Tartaglia, Rosa Amoroso, Stefania Fulle   +9 more
doaj   +1 more source

Novel fluorinated amino-stilbenes and their solid-state photodimerization

, 2010
We synthesized a series of polyfluoro-amino-stilbenes in satisfactory yields by Wittig reaction of 4-piperazinyl-benzalhehydes with pentafluoro-benzylidene-triphenyl-phosphorane and we analyzed the photochemical behavior of these stilbenes in the solid ...
Antonio Papagni, M. Moret, Luciano Miozzo, A. Papagni, Paola Del Buttero, Silvia Rizzato, Chiara Bertarelli, M. T. Pryce, Massimo Moret, L. Miozzo, Mary T. Pryce, S. Rizzato, P. Del Buttero, BERTARELLI, CHIARA   +13 more
core   +1 more source