Results 11 to 20 of about 10,398 (215)
Calmodulin dissociates the STIM1-Orai1 complex and STIM1 oligomers [PDF]
Nature Communications, 2017 Store-operated calcium entry (SOCE) is elicited by the interaction of oligomerized STIM1 with plasma membrane Orai channels. Here, the authors show that this process is regulated by calmodulin, which binds STIM1 and disassembles the STIM1-Orai1 complex ...
Xin Li +8 more
doaj +4 more sources
The STIM1 Phosphorylation Saga
Cell Calcium, 2022 Store-operated Ca2+ entry (SOCE) is a Ca2+ influx pathway present in practically every cell type in metazoans and mediates a variety of physiological functions.
Khaled Machaca (194372) +1 more
core +3 more sources
STIM1 is cleaved by calpain [PDF]
FEBS Letters, 2015 Store-operated calcium entry (SOCE) is a pathway that moves Ca2+ across the plasma membrane and is mediated by two major proteins, STIM1 and Orai1.
Prins, Daniel, Michalak, Marek
core +3 more sources
STIM1 Phosphorylation at Y361 Recruits Orai1 to STIM1 Puncta and Induces Ca2+ Entry [PDF]
Scientific Reports, 2017 Store-operated Ca2+ entry (SOCE) mediates the increase in intracellular calcium (Ca2+) in endothelial cells (ECs) that regulates several EC functions including tissue-fluid homeostasis.
Stefan Feske +7 more
core +3 more sources
S417 in the CC3 region of STIM1 is critical for STIM1-Orai1 binding and CRAC channel activation
Life Science Alliance, 2023 This study shows that S417 of STIM1 plays an essential role in STIM1 C-terminus–Orai1 interaction and CRAC channel activation. It also presents new findings about 2-APB’s action on CRAC channel, which provides a tool for better understanding of SOCE ...
Tao Yu +6 more
doaj +3 more sources
Amplification of CRAC current by STIM1 and CRACM1 (Orai1). [PDF]
Nature Cell Biology, 2006 Depletion of intracellular calcium stores activates store-operated calcium entry across the plasma membrane in many cells. STIM1, the putative calcium sensor in the endoplasmic reticulum, and the calcium release-activated calcium (CRAC) modulator CRACM1 (
Koomoa, Dana L +19 more
core +4 more sources
POST, partner of stromal interaction molecule 1 (STIM1), targets STIM1 to multiple transporters [PDF]
Proceedings of the National Academy of Sciences, 2011 Specialized proteins in the plasma membrane, endoplasmic reticulum (ER), and mitochondria tightly regulate intracellular calcium. A unique mechanism called store-operated calcium entry is activated when ER calcium is depleted, serving to ...
Luba Krapivinsky +4 more
core +3 more sources
eLife, 2021 Harnessing single-molecule FRET illuminates the structural changes necessary for a protein to fine-tune the influx of calcium when reserves inside a cell run low.
Marc Fahrner, Christoph Romanin
openaire +3 more sources
Expression of ORAI1 and STIM1 genes in blood of patients with pulmonary tuberculosis [PDF]
, 2021 This study aimed to detect the expression level of ORAI1 and STIM1 genes in blood of patients with bilateral pulmonary tuberculosis (TB) in comparison with the control group.
Oksana Kolesova +7 more
core +1 more source
lyons89/stim1-data-in-brief: STIM1-DIB
, 2022 Full Changelog: https://github.com/lyons89/stim1-data-in-brief/commits/0.
Scott Lyons
core +1 more source