Results 121 to 130 of about 10,284 (252)

Orai1 and Orai3 act through distinct signalling axes to promote stemness and tumorigenicity of breast cancer stem cells

Stem Cell Research & Therapy
Background One of major challenges in breast tumor therapy is the existence of breast cancer stem cells (BCSCs). BCSCs are a small subpopulation of tumor cells that exhibit characteristics of stem cells. BCSCs are responsible for progression, recurrence,
Duan Zhuo, Zhenchuan Lei, Lin Dong, Andrew Man Lok Chan, Jiacheng Lin, Liwen Jiang, Beibei Qiu, Xiaohua Jiang, Youhua Tan, Xiaoqiang Yao   +9 more
doaj   +1 more source

The NMDA receptor regulates integrin activation, ATP release and arterial thrombosis through store-operated Ca²⁺ entry in platelets. [PDF]

Front Cardiovasc Med, 2023
Reusswig F, Yilmaz M, Brechtenkamp M, Krueger I, Metz LM, Klöcker N, Lammert E, Elvers M.   +7 more
europepmc   +1 more source

Machine Learning‐Assisted KCl‐CaCl2‐LiCl Electrolyte Design for Low‐Temperature, High‐Performance Calcium‐Based Liquid Metal Batteries

Advanced Science, EarlyView.
A machine learning‐assisted framework optimizes the KCl‐CaCl2‐LiCl ternary electrolyte. The optimized 13:35:52 mol% composition enables Ca‐based liquid metal batteries to operate stably at 480 °C, with >99.5% coulombic efficiency, ultralow self‐discharge, and excellent cycling stability, advancing low‐temperature large‐scale energy storage.
Xinglin Zhou, Lei Huang, Yan Zhou, Xiaohui Ning   +3 more
wiley   +1 more source

Dystonia caused by ANO3 variants is due to attenuated Ca2+ influx by ORAI1

BMC Medicine
Background Dystonia is a common neurological hyperkinetic movement disorder that can be caused by mutations in anoctamin 3 (ANO3, TMEM16C), a phospholipid scramblase and ion channel.
Jiraporn Ousingsawat, Khaoula Talbi, Hilario Gómez-Martín, Anne Koy, Alberto Fernández-Jaén, Hasan Tekgül, Esra Serdaroğlu, Juan Darío Ortigoza-Escobar, Rainer Schreiber, Karl Kunzelmann   +9 more
doaj   +1 more source

Ca²⁺-induced myelin pathology precedes axonal spheroid formation and is mediated in part by store-operated Ca²⁺ entry after spinal cord injury. [PDF]

Neural Regen Res, 2023
Ames S, Adams K, Geisen ME, Stirling DP.
europepmc   +1 more source

Robust Amorphous MOF‐Based Aerogels Digital Biosensor for Sensitive Detection of Organophosphate Pesticides

Advanced Science, EarlyView.
We report a robust aerogel digital biosensor by integrating an enzyme‐mediated amorphous MOF within an aerogel matrix for on‐site pesticide detection. The enzyme‐mediated assembly strategy enables in situ tailoring of MOF into a porous amorphous structure, achieving both high stability and activity.
Changshun Su, Xiangyu Zhai, Houru Li, Yijie Wang, Hongxia Li, Yueyao Jiang, Geyu Lu, Xu Yan   +7 more
wiley   +1 more source

The roles of transmembrane family proteins in the regulation of store-operated Ca²⁺ entry. [PDF]

Cell Mol Life Sci, 2022
Zhang N, Pan H, Liang X, Xie J, Han W.
europepmc   +1 more source

All‐Flex Plasma Patch for In Vivo Delivery of Reactive Species

Advanced Science, EarlyView.
A fully flexible plasma patch enables stable, conformal treatment on complex biological surfaces and enhances transdermal delivery of reactive species. This platform achieves significant tumor suppression in vivo and reveals coordinated regulation of calcium signaling, metabolism, and programmed cell death, providing a promising strategy for safe and ...
Luxiang Zhao, Abulaihaiti Tuergong, Hanshu Yang, Shuang Xue, An Yan, Mingzhen Wang, Weilong Song, Wenzhe Si, Ruixue Wang   +8 more
wiley   +1 more source

Enforced tethering elongates the cortical endoplasmic reticulum and limits store-operated Ca2+ entry.

J Cell Sci, 2022
Henry C, Carreras-Sureda A, Demaurex N.
europepmc   +1 more source

Chlamydia trachomatis suppresses host cell store-operated Ca²⁺ entry and inhibits NFAT/calcineurin signaling. [PDF]

Sci Rep, 2022
Chamberlain NB, Dimond Z, Hackstadt T.
europepmc   +1 more source