Results 131 to 140 of about 12,900 (288)

Store-Operated Ca2+ Entry is Essential for Brown Adipogenesis.

, 2019
Brown adipocytes are important for non-shivering thermogenesis, lipid homeostasis, and anti-obesity. Ca2+ signaling is essential for adipocytes differentiation, adipogenesis.
Lee, Sang Kwon, Park, Chan Young, Kim, Kyu Min, Lee, Yoon Young, Lee, Ah Reum, Park, Jun Hong, Jang, Ki Hyun, Jeong, Su Ji, Kweon, Yeong Cheon   +8 more
core  

Advances and Perspectives in Graphene‐Based Quantum Dots Enabled Neuromorphic Devices

Advanced Science, EarlyView.
Graphene‐based QDs are zero‐dimensional carbon nanomaterials with pronounced quantum confinement and tunable electronic structures. Herein, we summarize their synthesis strategies and functionalization methods, and highlight their functional roles and operating mechanisms in devices, as well as recent advances in neuromorphic electronics. We anticipate
Yulin Zhen, Wei Zeng, Zherui Zhao, JiYu Zhao, Ziyan Huang, Zhuo Chen, Kui Zhou, Guanglong Ding, Su‐Ting Han, Ye Zhou   +9 more
wiley   +1 more source

STIM1 promotes migration, phagosomal maturation and antigen cross-presentation in dendritic cells

Nature Communications, 2017
STIM proteins sense Ca2+ depletion in the ER and activate store-operated Ca2+-entry (SOCE) in response, a process associated with dendritic cell functions.
Paula Nunes-Hasler, Sophia Maschalidi, Carla Lippens, Cyril Castelbou, Samuel Bouvet, Daniele Guido, Flavien Bermont, Esen Y. Bassoy, Nicolas Page, Doron Merkler, Stéphanie Hugues, Denis Martinvalet, Bénédicte Manoury, Nicolas Demaurex   +13 more
doaj   +1 more source

Electrophysiological characterization of store-operated and agonist-induced Ca2+ entry pathways in endothelial cells [PDF]

, 2018
In endothelial cells, agonist-induced Ca2+ entry takes place via the store-operated Ca2+ entry pathway and/or via channel(s) gated by second messengers. As cell stimulation leads to both a partial Ca2+ store depletion as well as the production of second ...
Girardin, Nathalie, Antigny, Fabrice, Frieden, Maud   +2 more
core  

Ultrasound‐Responsive Piezoelectric Fibrous Membrane Promotes Neurological Recovery After TBI by Modulating Microglial Polarization via Restoring Mitochondrial Dynamic Homeostasis

Advanced Science, EarlyView.
We demonstrate a novel therapy for traumatic brain injury TBI using a LIPUS‐responsive Piezoelectric fibrous membrane. It targets microglial mitochondria via in situ electrical signals, restoring homeostasis and reducing oxidative stress to promote an anti‐inflammatory M2 phenotype.
Wei Li, Runzhe Huang, Qingyuan Wu, Pengbo Zhou, Dangli Ren, Jingjing Wang, Hanjie Niu, Zemeng Li, Hongtao Sun, Huiyu Liu   +9 more
wiley   +1 more source

Store-operated calcium entry in neuroglia

, 2014
Neuroglial cells are homeostatic neural cells. Generally, they are electrically non-excitable and their activation is associated with the generation of complex intracellular Ca2+ signals that define the "Ca2+ excitability" of glia.
Parpura, Vladimir, Verkhratsky, Alexei; id_orcid   +1 more
core   +1 more source

Remote Magnetomechanical Neuromodulation Uncovers Therapeutic Mechanisms for Alleviating Parkinsonian Symptoms in Freely Moving Mice

Advanced Science, EarlyView.
Magnetomechanical neuromodulation using magnetic nanodiscs enables remote activation of neurons. In a hemiparkinsonian mouse model, alternating magnetic fields actuate the nanodiscs to generate torque that opens mechanosensitive ion channels within the subthalamic nucleus, thereby modulating basal ganglia motor circuitry.
Anouk Wolters, Lorenzo Signorelli, Christian Herff, Sophia Gimple, Renzo Riemens, Gunter Kenis, Kim Rijkers, Hamed Shabani, Jyh‐Jang Sun, Yasin Temel, Hans Clusmann, Danijela Gregurec, Sarah‐Anna Hescham   +12 more
wiley   +1 more source

Store-Operated Ca²⁺ Entry as a Putative Target of Flecainide for the Treatment of Arrhythmogenic Cardiomyopathy. [PDF]

J Clin Med, 2023
Moccia F, Brunetti V, Soda T, Faris P, Scarpellino G, Berra-Romani R.   +5 more
europepmc   +1 more source

Untersuchung TRPC-modulierender Gestagene und Proteine [PDF]

, 2008
In the first part of this study, we have identified the two steroid hormones progesterone and norgestimate as novel TRPC channel blockers. Both substances blocked TRPC-mediated Ca2+ influx with micromolar activities in fluorometric measurements.
Miehe, Susanne
core  

Flexoelectricity in Photoconversion: Fundamentals, Materials, and Outlooks

Advanced Science, EarlyView.
Mechanical bending of a flexible cantilever induces a strain gradient in the photoactive material. The resulting flexoelectric field couples with photovoltaic and photoconductive effects, modulating charge generation, separation, and collection. A comparative analysis of oxide perovskites, halide perovskites, and two‐dimensional materials is presented,
Xiang Huang, Feng Li, Rongkun Zheng
wiley   +1 more source