Results 191 to 200 of about 91,465 (249)

Generative AI as a conditional job resource under job demands in academic knowledge work: directed content analysis using the job demands-resources framework. [PDF]

Front Artif Intell
Çögenli MZ.
europepmc   +1 more source

SuFEx‐Enabled Reprogramming of Flavonoids for Selective α‐Glucosidase Covalent Inhibition

Advanced Science, EarlyView.
Selective inhibition of intestinal α‐glucosidase remains limited by poor enzyme specificity and off‐target metabolic effects. Here, SuFEx click chemistry is used to reprogram natural flavonoids into covalent inhibitors with enhanced α‐glucosidase selectivity and controlled reactivity. This strategy enables effective regulation of carbohydrate digestion
Fengyu Guo, Liwei Zhang, Minlong Wang, Yanjin Du, Tianyu Zhang, Hao Chen, Jiazeng Sun, Yang Yu, Zude He, Jie An, Xiaoxu Zhang, Weilin Lin, Fazheng Ren, Pengjie Wang, Ping Liu   +14 more
wiley   +1 more source

Long‐Term Ambient Benzene Exposure and Brain Disorders Among Urban Adults: Effect Modification by Genetic Susceptibility and Potential Mediation by Plasma Proteins

Advanced Science, EarlyView.
Low‐level ambient benzene exposure is associated with increased risks of multiple brain disorders in urban adults. Genetic susceptibility modifies these associations, while plasma proteomics points to potential biological pathways linking benzene exposure to adverse brain health.
Jianhui Guo, Xia Zhong, Petros Koutrakis, Carolina L. Zilli Vieira, Feifei Si, Yaqi Wang, Xinyao Lian, Yi Fan, Zhaokun Wang, Shaodan Huang, Jing Li   +10 more
wiley   +1 more source

Assessing entrepreneurial transformation in agricultural universities using hybrid multi-criteria decision-making. [PDF]

Sci Rep
Far ST, Rezaei-Moghaddam K, Zibaei M, Dallago B.   +3 more
europepmc   +1 more source

Melatonin Alleviates Graft Biliary Fibrosis by Inhibiting VIM+ Cholangiocyte Subcluster via Hypoxia/TGF‐β‐CREM‐VIM Axis

Advanced Science, EarlyView.
Single‐cell RNA sequencing verified the presence of the VIM+ biliary epithelial cell (BEC) in the bile ducts of NAS patients. The hypoxia/TGF‐β‐CREM‐VIM axis mediated phenotypic switch toward VIM+ BEC is validated using a hypoxia/TGF‐β‐stimulated cellular model, a rat liver transplantation model, BEC‐specific Crem conditional knockout rats, and BEC ...
Zhaoyi Wu, Nengsheng Fu, Zhongxin Huang, Yu Mou, Ensi Ma, Xiaoshi Wang, Tian Dong, Yujun Zhang, Danqing Liu, Di Jiang, Jingya Kuang, Rui Liao, Yifeng Tao, Leida Zhang, Chengcheng Zhang   +14 more
wiley   +1 more source

National Public Health Institutes Organizational Strengthening Module Framework: Applying Organizational Development Principles. [PDF]

Ann Glob Health
Hansoti B, Stodola C, Ridhi S, Adhikari B, Engineer C, Bratton S, Carnevale C, Gilayeneh JSM, Chilengi R, Bennett S.   +9 more
europepmc   +1 more source

Readiness Assessment for AI in Nursing Care Projects: Multimethods Study. [PDF]

JMIR Nurs
Seibert K, Domhoff D, Altona J, Jäger S, Bießmann F, Nowak A, Gubser R, Schulte-Althoff M, Fürstenau D, Pohle J, Bergmann L, Walter D, Beier K, Borchers D, Wolf-Ostermann K.   +14 more
europepmc   +1 more source

Public Health Responsible AI Capability (PH-RAIC) Framework: A Conceptual Model for Integrating AI into Public Health Agencies. [PDF]

Healthcare (Basel)
Zahid A, Sharma R, Ahmed R.
europepmc   +1 more source

Measuring organisational readiness for health system change in South Africa using the European Foundation for Quality Management Excellence Model (EFQM). [PDF]

PLOS Glob Public Health
Masike MA, Mahomed OH.
europepmc   +1 more source