Results 71 to 80 of about 139,184 (387)

Effective Penetration of the Oxidized Keratin‐Rebonding Materials Into Hair Shafts Based on Charge Conversion

open access: yesAdvanced Healthcare Materials, EarlyView.
We have developed a smart hair‐repair ingredient based on β‐carboxylic acid amide that undergoes negative‐to‐positive charge conversion under mildly acidic conditions. The initial negative charge facilitates deep penetration into the hair fiber, while the subsequent positive charge enables re‐bonding with sulfonate groups in damaged hair keratin.
Sunyoung Kang   +8 more
wiley   +1 more source

Status of surfactants as penetration enhancers in transdermal drug delivery

open access: yesJournal of Pharmacy and Bioallied Sciences, 2012
Surfactants are found in many existing therapeutic, cosmetic, and agro-chemical preparations. In recent years, surfactants have been employed to enhance the permeation rates of several drugs via transdermal route.
Iti Som, Kashish Bhatia, Mohd. Yasir
doaj   +1 more source

Effect of different thickness of keratin layer of ductus papillaris on state of parenchyma in cow udder [PDF]

open access: yesVeterinarski Glasnik, 2011
Ductus papillaris presents the frontline of defense of the mammary gland against the penetration of microorganisms into the milk cystern and the mammary gland parenchyma.
Davidov Ivana   +4 more
doaj   +1 more source

Nanosuspension-Based Dissolvable Microneedle Arrays to Enhance Diclofenac Skin Delivery

open access: yesPharmaceutics, 2023
Applying a formulation on the skin represents a patient-acceptable and therapeutically effective way to administer drugs locally and systemically. However, the stratum corneum stands as an impermeable barrier that only allows a very limited number of ...
Luca Casula   +10 more
doaj   +1 more source

Opportunities for topical antimicrobial therapy: permeation of canine skin by fusidic acid [PDF]

open access: yes, 2017
BACKGROUND: Staphylococcal infection of the canine epidermis and hair follicle is amongst the commonest reasons for antimicrobial prescribing in small animal veterinary practice.
A Loeffler   +29 more
core   +5 more sources

Living Materials Approach for In Situ Bio‐Polymers Production Using Bacillus Paralicheniformis in Microneedles

open access: yesAdvanced Healthcare Materials, EarlyView.
Dissolvable microneedle (MN) device containing Bacillus paralicheniformis. The polymeric matrix encapsulates and protects the bacteria, preserving their viability while enabling in situ production and release of γ‐polyglutamic acid. The bacteria are delivered into the skin via 500 µm‐long microneedles, and remain detectable on the skin 24 h post ...
Caroline Hali Alperovitz   +3 more
wiley   +1 more source

Amino acids disrupt calcium-dependent adhesion of stratum corneum.

open access: yesPLoS ONE, 2019
In the stratum corneum, the intercellular junction made up of cadherin proteins provides the structural integrity of the framework. Ca2+ ions are known to play a key role in maintaining this junction. In this study, we hypothesized that Ca2+ chelation in
Jin-Hyun Kim   +7 more
doaj   +1 more source

Stratum corneum cytokine levels in mycosis fungoides [PDF]

open access: hybrid, 2022
Anh Ly Nguyen   +6 more
openalex   +1 more source

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

open access: yesAdvanced Healthcare Materials, EarlyView.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández   +4 more
wiley   +1 more source

The pH of the skin surface and its impact on the barrier function [PDF]

open access: yes, 2006
The `acid mantle' of the stratum corneum seems to be important for both permeability barrier formation and cutaneous antimicrobial defense. However, the origin of the acidic pH, measurable on the skin surface, remains conjectural.
Abeck D   +41 more
core   +1 more source

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