Anthocyanins are natural colorants with antioxidant properties, shown to inhibit photoaging reactions and reduce symptoms of some skin diseases. However, little is known about their penetration through the stratum corneum, a prerequisite for bioactivity.
Alexandra Westfall +3 more
doaj +1 more source
Opportunities for topical antimicrobial therapy: permeation of canine skin by fusidic acid [PDF]
BACKGROUND: Staphylococcal infection of the canine epidermis and hair follicle is amongst the commonest reasons for antimicrobial prescribing in small animal veterinary practice.
A Loeffler +29 more
core +5 more sources
Highly Biomimetic Ectodermal Epithelial Organoids for Epithelial Barrier Stimulation Assays
ABSTRACT Evaluating the potential toxicity of pharmaceuticals and biomaterials to ectodermal epithelia, such as the oral mucosa and skin, is indispensable in pre‐clinical assessments. However, this remains a challenge primarily owing to the lack of physiologically relevant and accurate screening models.
Yiming Chen +13 more
wiley +1 more source
Study on the lipid organization of stratum corneum lipid models by (cryo-) electron diffraction
The barrier function of the skin resides in the stratum corneum (SC). This outermost layer consists of protein-rich corneocytes and lipid-rich intercellular domains.
G.S.K. Pilgram +4 more
doaj +1 more source
Universal in vivo Textural Model for Human Skin based on Optical Coherence Tomograms
Currently, diagnosis of skin diseases is based primarily on visual pattern recognition skills and expertise of the physician observing the lesion. Even though dermatologists are trained to recognize patterns of morphology, it is still a subjective visual
Adabi, Saba +7 more
core +2 more sources
Wound healing and hyper-hydration - a counter intuitive model [PDF]
Winters seminal work in the 1960s relating to providing an optimal level of moisture to aid wound healing (granulation and re-epithelialisation) has been the single most effective advance in wound care over many decades.
Atiyeh B.S. +23 more
core +1 more source
Therapeutic evaluation of homeopathic treatment for canine oral papillomatosis [PDF]
Aim: A study was conducted to evaluate the ameliorative potential of homeopathic drugs in combination (Sulfur 30C, Thuja 30C, Graphites 30C, and Psorinum 30C) in 16 dogs affected with oral papillomatosis which was not undergone any previous treatment ...
Kumar, M. Asok +5 more
core +2 more sources
Tracking of [14C]Polystyrene Nanoplastics in Pregnant Mice
This study investigates [14C]polystyrene nanoplastic ([14C]PS) translocation in late‐stage pregnant mice after intranasal (0.5 mg of [14C]PS on GD12, GD14, and GD16, n = 6) and intravenous administration (1.5 mg of [14C]PS on GD16, n = 6). 14C‐radiolabel allows quantitative tracking of unmodified polystyrene nanoplastics.
Olga Khaybullina +2 more
wiley +1 more source
Vesicular systems for delivering conventional small organic molecules and larger macromolecules to and through human skin [PDF]
The history of using vesicular systems for drug delivery to and through skin started nearly three decades ago with a study utilizing phospholipid liposomes to improve skin deposition and reduce systemic effects of triamcinolone acetonide.
El Maghraby, Gamal M. +1 more
core +1 more source
The Elephant Trunk Skin Inspires a Highly Sensitive and Deformable, Yet Robust, Armor Skin
The study presents the elephant trunk‐inspired armor skin with tactile sensing (ETATS). The ETATS architecture stretches and compresses while resisting puncture and tear, and it enables optical detection of pressure and lateral strain. Morphology‐based decoupling of strain and pressure paves the way to sensitive and deformable, yet robust, soft‐robotic
Jun Chang Yang +3 more
wiley +1 more source

