Results 81 to 90 of about 139,184 (387)

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

TrichomeLess Regulator 3 is required for trichome initial and cuticle biosynthesis in Artemisia annua

Molecular Horticulture
Artemisinin is primarily synthesized and stored in the subepidermal space of the glandular trichomes of Artemisia annua. The augmentation of trichome density has been demonstrated to enhance artemisinin yield.
Boran Dong, Zihan Xu, Xingxing Wang, JinXing Li, Ying Xiao, Doudou Huang, Zongyou Lv, Wansheng Chen   +7 more
doaj   +1 more source

Utilizing Untargeted Lipidomics Technology to Elucidate Differences in Lipid Compositions Among Sensitive Dry, Sensitive Oily and Healthy Skin Types

Metabolites
Background: Sensitive skin exhibits impaired skin barrier function. The lipid composition of the skin, a pivotal element within the stratum corneum’s “brick-and-mortar” structure, plays a dual role: it is integral to cell differentiation processes and ...
Agui Xie, Xingjiang Zhang, Qing Huang, Jianxin Wu   +3 more
doaj   +1 more source

Impact of Alkanediols on Stratum Corneum Lipids and Triamcinolone Acetonide Skin Penetration

Pharmaceutics, 2021
Alkanediols are widely used as multifunctional ingredients in dermal formulations. In addition to their preservative effect, considering their possible impact on drug penetration is also essential for their use.
Melanie Sigg, Rolf Daniels
doaj   +1 more source

Low‐Temperature Fabrication of Thymosin β4‐Loaded Soluble Microneedles to Promote Wound Healing by Specific Binding to Downregulated Immune Regulators Vsig4 and IL22rɑ2

Advanced Healthcare Materials, EarlyView.
Schematic diagram depicting the fabrication and application of thymosin β4 (Tβ4)‐loaded microneedle patches for wound treatment. The Tβ4 was loaded into chitosan (CS) and sucrose MNs under mild conditions (4°C, 65% relative humidity). The Tβ4 MN patch specifically binds to the downregulated immune regulators Vsig4 and IL22rα2, thereby accelerating ...
Shilong He, Mei Yuan, Changkang Feng, Yixuan Zhang, Jinjing Che   +4 more
wiley   +1 more source

Degree of Skin Barrier Disruption Affects Lipid Organization in Regenerated Stratum Corneum

Acta Dermato-Venereologica, 2018
Previously, a skin barrier repair model was developed to examine the effect of formulations on the lipid properties of compromised skin. In this model, the lipid organization mimics that of several skin diseases with impaired skin barrier and less dense ...
Tineke Berkers, Dani Visscher, Gert S. Gooris, Joke A. Bouwstra   +3 more
doaj   +1 more source

In vivo human skin penetration of (–)-epigallocatechin-3-gallate from topical formulations

Acta Pharmaceutica, 2014
The aim of the study was to examine the effect of topical vehicles on the in vivo human stratum corneum penetration of the antioxidant and skin photoprotective agent (-)-epigallocatechin-3-gallate (EGCG).
Scalia Santo, Trotta Valentina, Bianchi Anna   +2 more
doaj   +1 more source

Ex Vivo and In Vivo Assessment of the Penetration of Topically Applied Anthocyanins Utilizing ATR-FTIR/PLS Regression Models and HPLC-PDA-MS

Antioxidants, 2020
Anthocyanins are natural colorants with antioxidant properties, shown to inhibit photoaging reactions and reduce symptoms of some skin diseases. However, little is known about their penetration through the stratum corneum, a prerequisite for bioactivity.
Alexandra Westfall, Gregory T. Sigurdson, Luis E. Rodriguez-Saona, M. Mónica Giusti   +3 more
doaj   +1 more source

Nanopartículas Poliméricas en Dermocosmética [PDF]

, 2015
Indexación: Web of Science; Scielo.Recent advances in the fields of biomaterials and nanotechnology have allowed the development of advanced nanoparticles for biomedical applications. Despite a vast number of nanostructures such as liposomes, solid­lipid
Bahamonde-Norambuena, D., Cantin, Mario, Molina-Pereira, A., Muñoz, M., Vilos, Cristian, Zepeda, Katherine   +5 more
core   +1 more source

Therapeutic evaluation of homeopathic treatment for canine oral papillomatosis [PDF]

, 2020
Aim: A study was conducted to evaluate the ameliorative potential of homeopathic drugs in combination (Sulfur 30C, Thuja 30C, Graphites 30C, and Psorinum 30C) in 16 dogs affected with oral papillomatosis which was not undergone any previous treatment ...
Kumar, M. Asok, Pavulraj, Selvaraj, Raj, P. Albert Arockia, Sabithabanu, S., Sangeetha, S., Shanmugapriya, R.   +5 more
core   +2 more sources